scholarly journals Assessment of coronary microvascular dysfunction: An integral part of risk-stratification in Takotsubo cardiomyopathy - A response

2020 ◽  
Vol 39 (6) ◽  
pp. 359-360
Author(s):  
Jeremias Bayón ◽  
Alejandro Gutierrez-Barrios ◽  
Carlos Gonzalez-Juanatey
Keyword(s):  
Risk Stratification ◽  
Takotsubo Cardiomyopathy ◽  
Microvascular Dysfunction ◽  
Coronary Microvascular Dysfunction

scholarly journals Takotsubo Cardiomyopathy: One More Angiographic Evidence of Microvascular Dysfunction

2018 ◽  
Vol 2018 ◽  
pp. 1-6 ◽  
Author(s):  
Marco Loffi ◽  
Andrea Santangelo ◽  
Martin Kozel ◽  
Viktor Kocka ◽  
Tomas Budesinsky ◽  
...  
Keyword(s):  
Myocardial Perfusion ◽  
Coronary Arteries ◽  
Takotsubo Cardiomyopathy ◽  
Coronary Flow ◽  
Microvascular Dysfunction ◽  
Control Group ◽  
Coronary Microvascular Dysfunction ◽  
Microvascular Angina ◽  
Timi Frame Count ◽  
Angiographic Evidence

Background. Takotsubo cardiomyopathy (TC) aetiology has not been completely understood yet. One proposed pathogenic mechanism was coronary microvascular dysfunction (MVD). This study compared coronary flow and myocardial perfusion in patients with TC, microvascular angina (MVA), and a control group (CG). Methods. Out of 42 consecutive patients presented to our centre with TC from 2013 to 2017; we retrospectively selected 27 patients. We compared them with a sex- and age-matched group of 27 MVA cases and 27 patients with normal coronary arteries (CG). The flow was evaluated in the three coronary arteries as TIMI flow and TIMI frame count (TFC). Myocardial perfusion was studied with Blush-Score and Quantitative Blush Evaluator (QuBE). Results. TFC, in TC, revealed flow impairment in the three arteries compared to the CG (left anterior descending artery (LAD): 22±8, 15±4; p=0.001) (right coronary artery: 12±4, 10±3; p=0,025) (left circumflex: 14±4, CG 11±3; p=0,006). QuBE showed myocardial perfusion impairment in the LAD territory in TC comparing with both the CG (8,9 (7,2–11,5) versus 11,4 (10–15,7); p=0,008) and the MVA group (8,9 (7,2–11,5) versus 13,5 (10–16); p=0,006). Conclusions. Our study confirmed that coronary flow is impaired in TC, reflecting a MVD. Myocardial perfusion defect was detected only in the LAD area.

scholarly journals Role of Coronary Microvascular Dysfunction in Takotsubo Cardiomyopathy

2016 ◽  
Vol 80 (2) ◽  
pp. 299-305 ◽  
Author(s):  
Cristiana Vitale ◽  
Giuseppe MC Rosano ◽  
Juan Carlos Kaski
Keyword(s):  
Takotsubo Cardiomyopathy ◽  
Microvascular Dysfunction ◽  
Coronary Microvascular Dysfunction

Coronary microvascular dysfunction

2020 ◽  
Vol 68 (2) ◽  
Author(s):  
Vincenzo Sucato ◽  
Giuseppina Novo ◽  
Antonino Saladino ◽  
Salvatore Evola ◽  
Alfredo R. Galassi
Keyword(s):  
Microvascular Dysfunction ◽  
Coronary Microvascular Dysfunction
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