scholarly journals Left ventricular rigid body rotation in a diffuse large B-cell lymphoma patient with cardiac involvement: A case from the three-dimensional speckle-tracking echocardiographic MAGYAR-Path Study

2017 ◽  
Vol 36 (2) ◽  
pp. 145.e1-145.e5 ◽  
Author(s):  
Dóra Földeák ◽  
Anita Kalapos ◽  
Péter Domsik ◽  
Mária Sinkó ◽  
Nóra Szeleczki ◽  
...  
Keyword(s):  
Speckle Tracking ◽  
Cardiac Involvement ◽  
Cell Lymphoma ◽  
Three Dimensional ◽  
B Cell Lymphoma ◽  
Left Ventricular ◽  
Lymphoma Patient ◽  
Body Rotation ◽  
Large B Cell Lymphoma ◽  
Large B Cell

scholarly journals Diagnostic pitfalls: intramyocardial lymphoma metastasis mimics acute coronary syndrome in a diffuse large B cell lymphoma patient—case report

2021 ◽  
Vol 14 (1) ◽  
Author(s):  
Lilla Prenek ◽  
Klára Csupor ◽  
Péter Beszterczán ◽  
Krisztina Boros ◽  
Erika Kardos ◽  
...  
Keyword(s):  
B Cell ◽  
Cell Lymphoma ◽  
B Cell Lymphoma ◽  
Pericardial Fluid ◽  
Cardiac Tumors ◽  
Lymphoma Patient ◽  
Coronary Syndrome ◽  
Large B Cell Lymphoma ◽  
The Right ◽  
Large B Cell

Abstract Background Cardiac tumors are very uncommon compared to other cardiac diseases. Their clinical symptoms can vary from absent to non-specific. The most common symptoms are arrhythmias, blood flow obstruction due to valvular dysfunction, shortness of breath, systemic embolization, and accumulation of pericardial fluid. Hereby, we describe a very rare case of a diffuse large B cell lymphoma patient who presented with the symptoms and signs of acute coronary syndrome (ACS) but the patient’s complaints were caused by his intramyocardial lymphoma metastasis. Case presentation Forty-eight-year-old diffuse large B cell lymphoma patient was admitted to our emergency department with chest pain, effort dyspnea, and fever. The patient had normal blood pressure, blood oxygen saturation, sinus tachycardia, fever, crackles over the left lower lobe, novum incomplete right bundle branch block with Q waves and minor ST alterations, elevated C-reactive protein, high-sensitivity troponin-T, and d-dimer levels. Chest X-ray revealed consolidation on the left side and enlarged heart. Bed side transthoracic echocardiography showed inferior akinesis with pericardial fluid. Coronary angiography showed no occlusion or significant stenosis. Chest computed tomography demonstrated the progression of his lymphoma in the myocardium. He was admitted to the Department of Hematology for immediate chemotherapy and he reached complete metabolic remission, followed by allogeneic hematopoietic stem cell transplantation. Unfortunately, about 9 months later, he developed bone marrow deficiency consequently severe sepsis, septic shock, and multiple organ failure what he did not survive. Conclusions Our case demonstrates a very rare manifestation of a heart metastasis. ACS is an unusual symptom of cardiac tumors. But our patient’s intramyocardial lymphoma in the right atrium and ventricle externally compressed the right coronary artery and damaged the heart tissue, causing the patient’s symptoms which imitated ACS. Fortunately, the quick diagnostics and immediate aggressive chemotherapy provided the patient’s remission and suitability to further treatment.

Treatment with doxorubicin-based protocol in cardiac involvement diffuse large B-cell lymphoma: A case report

2021 ◽  
pp. 107815522110351
Author(s):  
Atakan Tekinalp ◽  
Taha U Kars ◽  
Hatice Z Dikici ◽  
Pınar D Yılmaz ◽  
Sinan Demircioğlu ◽  
...  
Keyword(s):  
Heart Failure ◽  
Case Report ◽  
B Cell ◽  
Cardiac Involvement ◽  
Cell Lymphoma ◽  
Vena Cava ◽  
Standardized Uptake Value ◽  
B Cell Lymphoma ◽  
Large B Cell Lymphoma ◽  
Large B Cell

Introduction Cardiac involvement in diffuse large B-cell lymphoma is a rare entity in non-Hodgkin lymphomas. Symptoms are usually related to heart failure. Patients who are severely symptomatic due to cardiac mass could be considered treatment as soon as possible. In this report, we present a patient diagnosed with diffuse large B-cell lymphoma with cardiac involvement. Case Report A 61-year-old female patient was admitted to our unit with gastric biopsy diffuse large B-cell lymphoma. Computerized tomography of the chest and positron emission tomography/computed tomography demonstrated a neoplastic mass in the intra-atrial septum extended to inferior vena cava (5 × 4 cm in size and standardized uptake value maximum 24.6). She was in stage III and in the high-risk group. Because of pronounced heart failure findings associated with the mass-specific chemotherapy was planned early. Management & Outcome Although a fraction of ejection was 60% by echocardiography before the treatment, she had a cardiac risk for doxorubicin due to being over 60 years old and hypertension. Complete remission was achieved after three cycles of rituximab–cyclophosphamide–doxorubicin–vincristine and methylprednisolone protocol including doxorubicin. Treatment was completed with six cycles and she was followed up for three months. Discussion Because of the cardiotoxicity of doxorubicin-based protocols, patients should be evaluated according to cardiac functions before and during the chemotherapy.

scholarly journals Utility of Routine Left Ventricular Ejection Fraction Measurement Before Anthracycline-Based Chemotherapy in Patients With Diffuse Large B-Cell Lymphoma

2012 ◽  
Vol 8 (6) ◽  
pp. 336-340 ◽  
Author(s):  
Amber L. Conrad ◽  
Jacob D. Gundrum ◽  
Vicki L. McHugh ◽  
Ronald S. Go
Keyword(s):  
Left Ventricular Ejection Fraction ◽  
B Cell ◽  
Cell Lymphoma ◽  
B Cell Lymphoma ◽  
Left Ventricular ◽  
Left Ventricular Ejection ◽  
Ventricular Ejection Fraction ◽  
Large B Cell Lymphoma ◽  
Fraction Measurement ◽  
Large B Cell

The authors' findings challenge the utility of routine LVEF measurement in patients with diffuse large B-cell lymphoma before anthracycline-based chemotherapy.

scholarly journals Intravascular Large B-cell Lymphoma with Left Ventricular Dysfunction

2008 ◽  
Vol 97 (7) ◽  
pp. 1666-1668
Author(s):  
Toshimi Imai ◽  
Yoshioki Nishimura ◽  
Mitsunobu Murata ◽  
Toshinobu Saitou ◽  
Keiji Yamamoto ◽  
...  
Keyword(s):  
B Cell ◽  
Left Ventricular Dysfunction ◽  
Ventricular Dysfunction ◽  
Cell Lymphoma ◽  
B Cell Lymphoma ◽  
Left Ventricular ◽  
Large B Cell Lymphoma ◽  
Large B Cell

scholarly journals Diagnostic Pitfalls: Intramyocardial Lymphoma Metastasis Mimics Acute Coronary Syndrome in A Diffuse Large B Cell Lymphoma Patient – Case Report

2020 ◽  
Author(s):  
Lilla Prenek ◽  
Klára Csupor ◽  
Péter Besztercán ◽  
Krisztina Boros ◽  
Erika Kardos ◽  
...  
Keyword(s):  
B Cell ◽  
Cell Lymphoma ◽  
B Cell Lymphoma ◽  
Pericardial Fluid ◽  
Cardiac Tumors ◽  
Lymphoma Patient ◽  
Coronary Syndrome ◽  
Large B Cell Lymphoma ◽  
The Right ◽  
Large B Cell

Abstract Background: Cardiac tumors are very uncommon compared to other cardiac diseases. Their clinical symptoms can vary from absent to nonspecific. The most common symptoms are arrhythmias, blood flow obstruction due to valvular dysfunction, shortness of breath, systemic embolization, accumulation of pericardial fluid. Hereby, we describe a very rare case of a diffuse large B cell lymphoma patient who presented with the symptoms and signs of acute coronary syndrome (ACS) but the patient’s complaints were caused by his intramyocardial lymphoma metastasis.Case presentation: 48-year-old diffuse large B cell lymphoma patient was admitted to our emergency department with chest pain, effort dyspnea and fever. The patient had normal blood pressure, blood oxygen saturation, sinus tachycardia, fever, crackles over the left lower lobe, novum incomplete right bundle branch block with Q waves and minor ST alterations, elevated C-reactive protein, high-sensitivity troponin-T and d-dimer levels. Chest X-ray revealed consolidation on the left side and enlarged heart. Bed side transthoracic echocardiography showed inferior akinesis with pericardial fluid. Coronary angiography showed no occlusion or significant stenosis. Chest computed tomography demonstrated the progression of his lymphoma in the myocardium. He was admitted to the Department of Hematology for immediate chemotherapy and he reached complete metabolic remission, followed by allogeneic hematopoietic stem cell transplantation. Unfortunately, about 9 months later, he developed bone marrow deficiency consequently severe sepsis, septic shock and multiple organ failure what he did not survive.Conclusions: Our case demonstrates a very rare manifestation of a heart metastasis. ACS is an unusual symptom of cardiac tumors. But our patient’s intramyocardial lymphoma in the right atrium and ventricle externally compressed the right coronary artery, causing the patient’s symptoms which imitated ACS. Fortunately, the quick diagnostics and immediate aggressive chemotherapy provided the patient’s remission and suitability to further treatment.

Establishment of a novel CD20 negative mature B-cell line, WILL2, from a CD20 positive diffuse large B-cell lymphoma patient treated with rituximab

2009 ◽  
Vol 89 (3) ◽  
pp. 400-402 ◽  
Author(s):  
Takashi Sonoki ◽  
Yaqiong Li ◽  
Setsuko Miyanishi ◽  
Hirokazu Nakamine ◽  
Nobuyoshi Hanaoka ◽  
...  
Keyword(s):  
B Cell ◽  
Cell Line ◽  
Cell Lymphoma ◽  
B Cell Lymphoma ◽  
Lymphoma Patient ◽  
Large B Cell Lymphoma ◽  
Large B Cell

scholarly journals Right upper quadrant pain and mass in a 41-year-old previously healthy man: a presenting feature of HIV-associated extranodal diffuse large B cell lymphoma with cardiac involvement

2012 ◽  
Vol 2012 (apr28 1) ◽  
pp. bcr1120115217-bcr1120115217 ◽  
Author(s):  
A. Vivekanandarajah ◽  
V. R. Bhatt ◽  
B. Krishnarasa ◽  
S. Murukutla ◽  
A. Brenner ◽  
...  
Keyword(s):  
B Cell ◽  
Cardiac Involvement ◽  
Cell Lymphoma ◽  
B Cell Lymphoma ◽  
Quadrant Pain ◽  
Large B Cell Lymphoma ◽  
Healthy Man ◽  
Large B Cell
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