Impact of Acute Kidney Injury on Short- and Long-term Outcomes After Transcatheter Aortic Valve Implantation

2019 ◽  
Vol 72 (1) ◽  
pp. 21-29 ◽  
Author(s):  
Antonio C.B. Nunes Filho ◽  
Marcelo Katz ◽  
Carlos M. Campos ◽  
Luiz A. Carvalho ◽  
Dimytri A. Siqueira ◽  
...  
2015 ◽  
Vol 66 (1) ◽  
pp. 46-49 ◽  
Author(s):  
Antonio J. Muñoz-García ◽  
Erika Muñoz-García ◽  
Manuel F. Jiménez-Navarro ◽  
Antonio J. Domínguez-Franco ◽  
Juan H. Alonso-Briales ◽  
...  

2013 ◽  
Vol 111 (2) ◽  
pp. 231-236 ◽  
Author(s):  
Robert M.A. van der Boon ◽  
Alaide Chieffo ◽  
Nicolas Dumonteil ◽  
Didier Tchetche ◽  
Nicolas M. Van Mieghem ◽  
...  

2020 ◽  
Vol 2 (4) ◽  
pp. 38-40
Author(s):  
Adriano Dourado ◽  
Hilana Araújo ◽  
Roger Gonçalves Ribeiro

Artigo Original: Gender-Related Differences on Short- and Long-Term Outcomes of Patients Undergoing Transcatheter Aortic Valve Implantation. Autores: Katz M, Nunes Filho ACB, Caixeta A, Carvalho LA, Sarmento-Leite R, Lemos Neto PA, São Thiago LEK, Oliveira ADD, Marino MA, Tumelero RT, Perin MA, Abizaid A, Tarasoutchi F, Brito FS. On behalf of the Brazilian TAVI Registry investigators. Catheter Cardiovasc Interv. 2017 Feb 15;89(3):429-436.


2019 ◽  
Vol 40 (38) ◽  
pp. 3169-3178 ◽  
Author(s):  
Yaron Arbel ◽  
Eyal Ben-Assa ◽  
Daniela Puzhevsky ◽  
Batia Litmanowicz ◽  
Naama Galli ◽  
...  

Abstract Aims Acute kidney injury (AKI) is a common complication following transcatheter aortic valve implantation (TAVI) and is associated with increased risk for short- and long-term mortality. In patients undergoing percutaneous coronary intervention (PCI), forced diuresis with matched hydration has been shown to reduce the incidence of AKI by ∼50%. The aim of the present study was to evaluate whether forced diuresis with matched intravenous hydration reduces AKI in patients undergoing TAVI. Methods and results Reducing Acute Kidney Injury (REDUCE-AKI) was a single-centre, prospective, randomized, double-blind sham-controlled clinical trial, designed to examine the effect of an automated matched saline infusion with urine output for the prevention of AKI in patients undergoing TAVI. A total of 136 TAVI patients were randomized, 68 in each group. Mean age was 83.9 ± 5 years and 41.2% were males. There were no differences in baseline characteristics between the two groups. The rate of AKI was not statistically different between the groups (25% in the active group vs. 19.1% in the sham group, P = 0.408). There was a significant increase in long-term mortality in the active group (27.9% vs. 13. 2% HR 3.744, 95% CI 1.51–9.28; P = 0.004). The study was terminated prematurely by the Data Safety Monitoring Board for futility and a possible signal of harm. Conclusions Unlike in PCI, forced diuresis with matched hydration does not prevent AKI in patients undergoing TAVI, and might be associated with increased long-term mortality. Future studies should focus on understanding the mechanisms behind these findings. Clinicaltrials.gov registration NCT01866800, 30 April 2013.


2016 ◽  
Vol 89 (3) ◽  
pp. 429-436 ◽  
Author(s):  
Marcelo Katz ◽  
Antonio Carlos Bacelar Nunes Filho ◽  
Adriano Caixeta ◽  
Luiz Antonio Carvalho ◽  
Rogério Sarmento-Leite ◽  
...  

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