Stimuli-responsive copolymeric hydrogels based on oligo(ethylene glycol) dimethacrylate for biomedical applications: An optimisation study of pH and thermoresponsive behaviour

2021 ◽  
pp. 105140
Author(s):  
M. Krstic ◽  
Z. Rogic Miladinovic ◽  
T. Barudzija ◽  
A. Mladenovic ◽  
E. Suljovrujic
Keyword(s):  
Ethylene Glycol ◽  
Biomedical Applications ◽  
Ethylene Glycol Dimethacrylate ◽  
Glycol Dimethacrylate ◽  
Stimuli Responsive

scholarly journals Bacterial Nanocellulose and Its Surface Modification by Glycidyl Methacrylate and Ethylene Glycol Dimethacrylate. Incorporation of Vancomycin and Ciprofloxacin

Nanomaterials ◽  
2019 ◽  
Vol 9 (12) ◽  
pp. 1668 ◽  
Author(s):  
Elena Vismara ◽  
Andrea Bernardi ◽  
Chiara Bongio ◽  
Silvia Farè ◽  
Salvatore Pappalardo ◽  
...  
Keyword(s):  
Tissue Engineering ◽  
Ethylene Glycol ◽  
Biomedical Applications ◽  
Ethylene Glycol Dimethacrylate ◽  
Wound Dressings ◽  
Cross Linking ◽  
Glycol Dimethacrylate ◽  
Tissue Engineering Scaffolds ◽  
Bacterial Nanocellulose ◽  
Substitution Degree

Among nanocelluloses, bacterial nanocellulose (BNC) has proven to be a promising candidate in a range of biomedical applications, from topical wound dressings to tissue-engineering scaffolds. Chemical modifications and incorporation of bioactive molecules have been obtained, further increasing the potential of BNC. This study describes the incorporation of vancomycin and ciprofloxacin in BNC and in modified BNC to afford bioactive BNCs suitable for topical wound dressings and tissue-engineering scaffolds. BNC was modified by grafting glycidylmethacrylate (GMA) and further cross-linking with ethylene glycol dimethacrylate (EGDMA) with the formation of stable C–C bonds through a radical Fenton-type process that involves generation of cellulose carbon centred radicals scavenged by methacrylate structures. The average molar substitution degree MS (MS = methacrylate residue per glucose unit, measured by Fourier transform infrared (FT–IR) analysis) can be modulated in a large range from 0.1 up to 3. BNC-GMA, BNC-EGDMA and BNC-GMA-EGDMA maintain the hydrogel status until MS reaches the value of 1. The mechanical stress resistance increase of BNC-GMA and BNC-GMA-EGDMA of MS around 0.8 with respect to BNC suggests that they can be preferred to BNC for tissue-engineering scaffolds in cases where the resistance plays a crucial role. BNC, BNC-GMA, BNC-EGDMA and BNC-GMA-EGDMA were loaded with vancomycin (VC) and ciprofloxacin (CP) and submitted to release experiments. BNC-GMA-EGDMA of high substitution degree (0.7–1) hold up to 50 percentage of the loaded vancomycin and ciprofloxacin amount, suggesting that they can be further investigated for long-term antimicrobial activity. Furthermore, they were not colonized by Staphylococcus aureus (S.A.) and Klebsiella pneumonia (K.P.). Grafting and cross-linking BNC modification emerges from our results as a good choice to improve the BNC potential in biomedical applications like topical wound dressings and tissue-engineering scaffolds.

Gold (Au) selective adsorption using polyeugenol based ionic imprinted polymer with ethylene glycol dimethacrylate crosslink

2020 ◽  
Author(s):  
M. Cholid Djunaidi ◽  
Nor Basid Adiwibawa Prasetya ◽  
Didik Setiyo Widodo ◽  
Retno Ariadi Lusiana ◽  
Pardoyo
Keyword(s):  
Ethylene Glycol ◽  
Selective Adsorption ◽  
Ethylene Glycol Dimethacrylate ◽  
Glycol Dimethacrylate ◽  
Imprinted Polymer

scholarly journals Evaluation of the Ultraviolet-Curing Kinetics of Ultraviolet-Polymerized Oligomers Cured Using Poly (Ethylene Glycol) Dimethacrylate

Coatings ◽  
2018 ◽  
Vol 8 (3) ◽  
pp. 99 ◽  
Author(s):  
Ji-Won Park ◽  
Jong-Gyu Lee ◽  
Gyu-Seong Shim ◽  
Hyun-Joong Kim ◽  
Young-Kwan Kim ◽  
...  
Keyword(s):  
Ethylene Glycol ◽  
Curing Kinetics ◽  
Ethylene Glycol Dimethacrylate ◽  
Glycol Dimethacrylate ◽  
Poly Ethylene Glycol ◽  
Ultraviolet Curing ◽  
Poly Ethylene ◽  
Kinetics Of
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