Biodegradable polymers exhibiting temperature-responsive sol–gel transition as injectable biomedical materials

2013 ◽  
Vol 73 (7) ◽  
pp. 979-985 ◽  
Author(s):  
Koji Nagahama ◽  
Akihiro Takahashi ◽  
Yuichi Ohya
RSC Advances ◽  
2020 ◽  
Vol 10 (41) ◽  
pp. 24507-24514
Author(s):  
Peihong Li ◽  
Xueyan Dai ◽  
Lijie Qu ◽  
Yanlong Sui ◽  
Chunling Zhang

Oligo(lysine)-F127 hydrogels have a temperature-responsive sol–gel transition and pH-responsive micelle morphology.


2014 ◽  
Vol 46 (9) ◽  
pp. 632-635 ◽  
Author(s):  
Yasuyuki Yoshida ◽  
Akihiro Takahashi ◽  
Akinori Kuzuya ◽  
Yuichi Ohya

2015 ◽  
Vol 23 (7) ◽  
pp. 607-617 ◽  
Author(s):  
Qinqin Wang ◽  
Shouxin Liu ◽  
Weijuan Sheng ◽  
Naer Guang ◽  
Xuan Li

1994 ◽  
Vol 91 ◽  
pp. 901-908 ◽  
Author(s):  
H Zanni ◽  
P Nieto ◽  
L Fernandez ◽  
R Couty ◽  
P Barret ◽  
...  

Gels ◽  
2021 ◽  
Vol 7 (2) ◽  
pp. 36
Author(s):  
Emanuele Mauri ◽  
Sara Maria Giannitelli ◽  
Marcella Trombetta ◽  
Alberto Rainer

Nanogels represent an innovative platform for tunable drug release and targeted therapy in several biomedical applications, ranging from cancer to neurological disorders. The design of these nanocarriers is a pivotal topic investigated by the researchers over the years, with the aim to optimize the procedures and provide advanced nanomaterials. Chemical reactions, physical interactions and the developments of engineered devices are the three main areas explored to overcome the shortcomings of the traditional nanofabrication approaches. This review proposes a focus on the current techniques used in nanogel design, highlighting the upgrades in physico-chemical methodologies, microfluidics and 3D printing. Polymers and biomolecules can be combined to produce ad hoc nanonetworks according to the final curative aims, preserving the criteria of biocompatibility and biodegradability. Controlled polymerization, interfacial reactions, sol-gel transition, manipulation of the fluids at the nanoscale, lab-on-a-chip technology and 3D printing are the leading strategies to lean on in the next future and offer new solutions to the critical healthcare scenarios.


Langmuir ◽  
2021 ◽  
Author(s):  
Lucas S. Ribeiro ◽  
Renata L. Sala ◽  
Leticia A. O. de Jesus ◽  
Sandra A. Cruz ◽  
Emerson R. Camargo

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