scholarly journals Is the time interval between HCG administration and oocyte retrieval associated with oocyte retrieval rate?

2015 ◽  
Vol 31 (5) ◽  
pp. 625-632 ◽  
Author(s):  
Julia K. Bosdou ◽  
Efstratios M. Kolibianakis ◽  
Christos A. Venetis ◽  
Leonidas Zepiridis ◽  
Katerina Chatzimeletiou ◽  
...  
Keyword(s):  
Oocyte Retrieval ◽  
Time Interval ◽  
Retrieval Rate ◽  
Oocyte Retrieval Rate

Oocyte retrieval rate through repeated identical controlled ovarian stimulation cycles in donors.

2001 ◽  
Vol 76 (3) ◽  
pp. S129-S130
Author(s):  
C. Caligara ◽  
J. Navarro ◽  
F. Camargo ◽  
C. Simón ◽  
A. Pellicer ◽  
...  
Keyword(s):  
Ovarian Stimulation ◽  
Oocyte Retrieval ◽  
Controlled Ovarian Stimulation ◽  
Retrieval Rate ◽  
Oocyte Retrieval Rate

scholarly journals Comparison of Dydrogesterone and Medroxyprogesterone in the Progestin-Primed Ovarian Stimulation Protocol for Patients With Poor Ovarian Response

2021 ◽  
Vol 12 ◽  
Author(s):  
Junwei Zhang ◽  
Mingze Du ◽  
Zhen Li ◽  
Wenxia Liu ◽  
Bingnan Ren ◽  
...  
Keyword(s):  
Oocyte Retrieval ◽  
Ovarian Response ◽  
Fertilization Rate ◽  
Poor Ovarian Response ◽  
Retrieval Rate ◽  
Biochemical Pregnancy ◽  
Cancellation Rate ◽  
Baseline Characteristics ◽  
Viable Embryo ◽  
Oocyte Retrieval Rate

ObjectiveTo compare the clinical outcomes of dydrogesterone (DYG) and medroxyprogesterone (MPA) in the progestin-primed ovarian stimulation (PPOS) protocol for patients with poor ovarian response (POR).Patients and MethodsThis was a retrospective cohort study. Women with POR who underwent IVF/ICSI at the Reproductive Center of Third Affiliated Hospital of Zhengzhou University between January 2020 and January 2021 were included. The primary outcome measure of our study was the number of oocytes retrieved. The secondary outcome measures in the present study were the number of 2PN, number of available embryos, oocyte retrieval rate, fertilization rate, viable embryo rate per oocyte retrieved, cancellation rate and pregnancy outcomes of the first embryo transfer cycle, including the biochemical pregnancy, clinical pregnancy and miscarriage rates.ResultsIn total, 118 women underwent hMG +DYG protocols, and 692 women who underwent hMG +MPA met the Bologna criteria for POR. After baseline characteristics were balanced using the PSM model, 118 hMG +DYG protocols were matched to 118 hMG +MPA protocols, and the baseline characteristics were comparable between the two groups. The numbers of oocytes retrieved, 2PN, and available embryos and the oocyte retrieval rate, fertilization rate, viable embryo rate per oocyte retrieved and cancellation rate of the hMG+DYG and hMG+MPA protocols were comparable. Altogether, 66 women in the hMG+DYG group and 87 women in the hMG+MPA group underwent first embryo transfers. In the hMG+DYG group, 81.8% (54/66) of the patients underwent cleavage embryo transfers; similarly, 79.3% (69/87) of patients in the hMG+MPA group had cleavage embryo transfers (P=0.70).The biochemical pregnancy rate of the hMG+DYG group was 42.4%, and this was comparable to the rate in the hMG+DYG group, at 34.5% (P=0.32). The clinical pregnancy rates were similar between the two groups (36.4% vs. 31.0%, P=0.49), and there was no significant difference in the rate of miscarriage between the two groups (12.5% vs. 29.6%, P=0.14).ConclusionFor women with POR, the clinical outcome of the hMG + DYG group was similar to that of the hMG + MPA group, indicating that both combinations can be useful options for PPOS protocols.

scholarly journals Analyzing the risk factors for a diminished oocyte retrieval rate under controlled ovarian stimulation

2016 ◽  
Vol 16 (1) ◽  
pp. 40-44 ◽  
Author(s):  
Mayumi Nakamura ◽  
Yoshiki Yamashita ◽  
Atsushi Hayashi ◽  
Natsuho Saito ◽  
Masae Yu ◽  
...  
Keyword(s):  
Risk Factors ◽  
Ovarian Stimulation ◽  
Oocyte Retrieval ◽  
Controlled Ovarian Stimulation ◽  
Retrieval Rate ◽  
Oocyte Retrieval Rate

P–169 Does increasing the time interval between Oocyte-Retrieval and Oocyte-Denudation improve the results in ICSI cycles ?

2021 ◽  
Vol 36 (Supplement_1) ◽  
Author(s):  
M Singh ◽  
R Singh
Keyword(s):  
Pregnancy Rate ◽  
Embryo Quality ◽  
Oocyte Retrieval ◽  
Fertilization Rate ◽  
Clinical Pregnancy ◽  
Clinical Pregnancy Rate ◽  
Time Interval ◽  
Male Factor ◽  
Time Intervals ◽  
The Mean

Abstract Study question What should be the optimal time interval which elapses between oocyte retrieval and denudation followed by ICSI , for optimal results in ART cycles ? Summary answer Our study suggests that an optimum interval between oocyte retrieval and oocyte denudation followed by ICSI, leads to better results in ART cycles. What is known already It is widely accepted that the best timing for OPU is 34–39 hours after ovulation trigger. Some studies suggest that preincubation time before ICSI can be beneficial when it comes to fertilization and pregnancy rates while late ICSI (fertilization) may have negative results due to oocyte ageing. Other studies claim that there is no significant difference in ART results when ICSI is performed between 2–6 hours post Oocyte-Retrieval (OR) . Few studies state that 1–3 hours of COC-culture prior to denudation and oocyte injection is better as far as fertilization , embryo quality and improved oocyte cytoplasmic maturity is concerned. Study design, size, duration RCT of 234 ICSI cycles was carried out between 2017–2019. Patients were divided into two groups-: A- Early denudation with ICSI and B- Late denudation with ICSI.Both the groups were comparable in terms of female age, number of oocytes, day of transfer, number of embryos transferred and embryo quality. Fresh or frozen embryos were transferred , which were always derived from the same stimulation cycle. Exclusion criteria were : Severe male factor / TESA / PESA. Participants/materials, setting, methods 234 ICSI cycles with similar ovarian stimulation protocols were analyzed as per time range between triggering, OPU, denudation and ICSI. Patients were divided into two groups: A- Early denudation (1–2 hours after OPU) with ICSI (1–2 hours after denudation) and B- Late denudation (4–6 hours after Oocyte-Retrieval ) with ICSI (1–2 hours after denudation).Primary outcomes were oocyte maturation and fertilization rates and secondary outcomes were clinical pregnancy rate and abortion rates. Main results and the role of chance In group B ( Late denudation and ICSI), the mean fertilization rate was 67% and the Clinical Pregnancy rate was 46%. This was better than the mean fertilization rate of 56% and clinical pregnancy rate of 39% observed in group A ( Early denudation and ICSI). However the difference was not statistically significant. Therefore, ideal maturation rates were observed when denudation ( followed by ICSI ) was delayed and done 4–6 hours after Oocyte-Retrieval. In ICSI cycles in ART , ovarian stimulation is used to induce the simultaneous growth of multiple follicles, followed by final maturation and ovulation triggering with exogenous hCG. or GnRH-Agonist or both. Generally, oocyte retrieval (OR) is performed 34 - 36h later. In addition, 2–4 hours in culture of the cumulus oocyte complexes (COC) prior to oocyte injection is believed beneficial for fertilization and embryo quality, probably due to improved oocyte cytoplasmic maturity. However, in large ART centers with high workloads, following such definite time intervals is frequently very difficult. Limitations, reasons for caution In large busy centers , maintaining meticulous time intervals is difficult . As our study numbers are small, larger multicentric trials are required in order to confirm our findings and to provide more robust data . This data cannot be applied to IVM, TESE / PESE and severe male-factor infertility. Wider implications of the findings: To achieve a successful fertilization, both nuclear and cytoplasmic maturity are required. Our Study indicates that a slight delay in denudation following Oocyte-Retrieval , will yield a higher number of good quality oocytes. A higher success rate can also be expected due to more number of embryos available for transfer. Trial registration number Not applicable

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