Effects of the Diving Reflex Stimulation on the Ventilatory Response to Tracheal Irritation in Anaesthetized Rabbits

2011 ◽  
Vol 24 (3) ◽  
pp. e7-e8
Author(s):  
M. Poussel ◽  
S. Varechova ◽  
B. Chenuel ◽  
C. Schweitzer ◽  
C. Beyaert ◽  
...  
1985 ◽  
Vol 69 (6) ◽  
pp. 663-672 ◽  
Author(s):  
L. Adams ◽  
R. Lane ◽  
S. A. Shea ◽  
A. Cockcroft ◽  
A. Guz

1. This study investigates the mechanisms underlying the perception of breathlessness induced by hypoxia and hypercapnia in both naive normal subjects and patients with respiratory mechanical problems. 2. In normal subjects separately receiving both oscillating hypercapnic and hypoxic ventilatory stimulation, equivalent peak stimulus intensities in end-tidal gas were associated with a ‘damped’ ventilatory response when the frequency of stimulation was increased. A concomitant fall in peak breathlessness levels on a visual analogue scale was recorded in each case. 3. In normal subjects and patients, the voluntary copying of a ventilatory pattern recorded during oscillating hypercapnic stimulation was associated with a marked diminution or complete absence of breathlessness despite equivalent levels of peak ventilations achieved. 4. Voluntary copying of hypercapnic stimulated ventilation was not associated with any demonstrable change in the distribution of muscle movements between the chest wall and abdomen. 5. These results suggest that the intensity of breathlessness depends on the level of effective reflex stimulation of the respiratory-related neurones in the medulla. They cannot be explained solely in terms of perception of afferent neural information arising from either chemoreceptors or respiratory mechanoreceptors.


2003 ◽  
Vol 2 (1) ◽  
pp. 63-64
Author(s):  
H ADACHI ◽  
S SAKURAI ◽  
T TOYAMA ◽  
H HOSHIZAKI ◽  
S OSHIMA ◽  
...  

1960 ◽  
Vol XXXV (II) ◽  
pp. 245-252 ◽  
Author(s):  
G. P. van Rees ◽  
F. J. A. Paesi

ABSTRACT In the experiments reported in this paper the hypothesis that the decrease in the pituitary I. C. S. H.-content, which occurs after administration of steroid sex hormones in gonadectomized animals, is counteracted by a reflex stimulation of the hypophysis initiated by the operation has been investigated. If treatment with a low dose of testosterone propionate (100 μg) was started immediately after castration, the resulting decrease in the pituitary I. C. S. H.-content became more marked if the reflex stimulation of the hypophysis had been prevented. If, however, two months were allowed to elapse before the beginning of treatment, the presence or absence of this reflex was no longer of importance for the effect of testosterone propionate on the pituitary I. C. S. H.-content. And yet, in this case too, the decrease in the pituitary I. C. S. H.-content by testosterone propionate was less than in intact animals (see preceding paper). Hence this decrease appears to be counteracted by two factors: one rapidly occurring and short lasting, resulting from a reflex elicited by gonadectomy; the other gradually increasing in potency and possibly a direct consequence of the continued absence of pituitary inhibiting sex steroids.


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