Target and organ dose estimation from intensity modulated head and neck radiation therapy using 3 deformable image registration algorithms

2015 ◽  
Vol 5 (4) ◽  
pp. e317-e325 ◽  
Author(s):  
Akila Kumarasiri ◽  
Chang Liu ◽  
Farzan Siddiqui ◽  
Hualiang Zhong ◽  
Indrin J. Chetty ◽  
...  
Keyword(s):  
Radiation Therapy ◽  
Image Registration ◽  
Head And Neck ◽  
Deformable Image Registration ◽  
Organ Dose ◽  
Dose Estimation ◽  
Intensity Modulated ◽  
Head And Neck Radiation

scholarly journals Effects of full-neck volumetric-modulated arc therapyvssplit-field intensity-modulated head and neck radiation therapy on low neck targets and structures

2016 ◽  
Vol 89 (1062) ◽  
pp. 20160009 ◽  
Author(s):  
Shibu J Anamalayil ◽  
Boon-Keng K Teo ◽  
Alexander Lin ◽  
Robert A Lustig ◽  
Peter H Ahn
Keyword(s):  
Radiation Therapy ◽  
Head And Neck ◽  
Field Intensity ◽  
Intensity Modulated ◽  
Head And Neck Radiation

scholarly journals Evaluation of Deformable Image Registration Methods for Dose Monitoring in Head and Neck Radiotherapy

2015 ◽  
Vol 2015 ◽  
pp. 1-16 ◽  
Author(s):  
Bastien Rigaud ◽  
Antoine Simon ◽  
Joël Castelli ◽  
Maxime Gobeli ◽  
Juan-David Ospina Arango ◽  
...  
Keyword(s):  
Radiation Therapy ◽  
Image Registration ◽  
Head And Neck ◽  
Intensity Modulated Radiation Therapy ◽  
Deformable Image Registration ◽  
Free Form ◽  
Registration Accuracy ◽  
Dose Accumulation ◽  
Dose Monitoring ◽  
Dose Accuracy

In the context of head and neck cancer (HNC) adaptive radiation therapy (ART), the two purposes of the study were to compare the performance of multiple deformable image registration (DIR) methods and to quantify their impact for dose accumulation, in healthy structures. Fifteen HNC patients had a planning computed tomography (CT0) and weekly CTs during the 7 weeks of intensity-modulated radiation therapy (IMRT). Ten DIR approaches using different registration methods (demons or B-spline free form deformation (FFD)), preprocessing, and similarity metrics were tested. Two observers identified 14 landmarks (LM) on each CT-scan to compute LM registration error. The cumulated doses estimated by each method were compared. The two most effective DIR methods were the demons and the FFD, with both the mutual information (MI) metric and the filtered CTs. The corresponding LM registration accuracy (precision) was 2.44 mm (1.30 mm) and 2.54 mm (1.33 mm), respectively. The corresponding LM estimated cumulated dose accuracy (dose precision) was 0.85 Gy (0.93 Gy) and 0.88 Gy (0.95 Gy), respectively. The mean uncertainty (difference between maximal and minimal dose considering all the 10 methods) to estimate the cumulated mean dose to the parotid gland (PG) was 4.03 Gy (SD = 2.27 Gy, range: 1.06–8.91 Gy).

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