scholarly journals Gold Nanorods Based LSPR Biosensor for Label-Free Detection of Alpha-Fetoprotein

2011 ◽  
Vol 25 ◽  
pp. 67-70 ◽  
Author(s):  
Xia Xu ◽  
Yibin Ying ◽  
Yanbin Li
Keyword(s):  
Gold Nanorods ◽  
Alpha Fetoprotein ◽  
Label Free ◽  
Label Free Detection

Counterions-mediated gold nanorods-based sensor for label-free detection of poly(ADP-ribose) polymerase-1 activity and its inhibitor

2018 ◽  
Vol 259 ◽  
pp. 565-572 ◽  
Author(s):  
Shuangshuang Wu ◽  
Min Wei ◽  
Haitang Yang ◽  
Jiahui Fan ◽  
Wei Wei ◽  
...  
Keyword(s):  
Gold Nanorods ◽  
Label Free ◽  
Label Free Detection

DNA functionalized gold nanorods/nanoplates assembly as sensitive LSPR-based sensor for label-free detection of mercury ions

2013 ◽  
Vol 110 ◽  
pp. 485-488 ◽  
Author(s):  
Dandan Li ◽  
Guangchao Zheng ◽  
Xiaofeng Ding ◽  
Jin Wang ◽  
Jinhuai Liu ◽  
...  
Keyword(s):  
Gold Nanorods ◽  
Label Free ◽  
Mercury Ions ◽  
Label Free Detection

scholarly journals A sensitive label–free amperometric immunosensor for alpha-fetoprotein based on gold nanorods with different aspect ratio

2015 ◽  
Vol 5 (1) ◽  
Author(s):  
Chunyang Zhou ◽  
Dali Liu ◽  
Lin Xu ◽  
Qingling Li ◽  
Jian Song ◽  
...  
Keyword(s):  
Aspect Ratio ◽  
Gold Nanorods ◽  
Alpha Fetoprotein ◽  
Label Free ◽  
Amperometric Immunosensor

scholarly journals The Role of Surface Chemistry in the Efficacy of Protein and DNA Microarrays for Label-Free Detection: An Overview

Polymers ◽  
2021 ◽  
Vol 13 (7) ◽  
pp. 1026
Author(s):  
Elisa Chiodi ◽  
Allison M. Marn ◽  
Matthew T. Geib ◽  
M. Selim Ünlü
Keyword(s):  
Surface Chemistry ◽  
Surface Functionalization ◽  
Dna Microarrays ◽  
Label Free ◽  
Polymeric Coatings ◽  
Label Free Detection ◽  
Particle Imaging ◽  
Single Particle Imaging ◽  
The Impact

The importance of microarrays in diagnostics and medicine has drastically increased in the last few years. Nevertheless, the efficiency of a microarray-based assay intrinsically depends on the density and functionality of the biorecognition elements immobilized onto each sensor spot. Recently, researchers have put effort into developing new functionalization strategies and technologies which provide efficient immobilization and stability of any sort of molecule. Here, we present an overview of the most widely used methods of surface functionalization of microarray substrates, as well as the most recent advances in the field, and compare their performance in terms of optimal immobilization of the bioreceptor molecules. We focus on label-free microarrays and, in particular, we aim to describe the impact of surface chemistry on two types of microarray-based sensors: microarrays for single particle imaging and for label-free measurements of binding kinetics. Both protein and DNA microarrays are taken into consideration, and the effect of different polymeric coatings on the molecules’ functionalities is critically analyzed.

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