Production of thuringiensin by fed-batch culture of Bacillus thuringiensis subsp. darmstadiensis 032 with an improved pH-control glucose feeding strategy

2007 ◽  
Vol 42 (1) ◽  
pp. 52-56 ◽  
Author(s):  
Zhou Jing-Wen ◽  
Chang Ya-Fei ◽  
Xu Zheng-Hong ◽  
Yu Zi-Niu ◽  
Chen Shou-Wen
Keyword(s):  
Bacillus Thuringiensis ◽  
Batch Culture ◽  
Feeding Strategy ◽  
Ph Control ◽  
Fed Batch ◽  
Glucose Feeding ◽  
Bacillus Thuringiensis Subsp ◽  
Fed Batch Culture

pH control for fed-batch culture of Bacillus thuringiensis

1994 ◽  
Vol 8 (7) ◽  
Author(s):  
Jian-Zhong Jong ◽  
Wen-Teng Wu ◽  
Yew-Min Tzeng
Keyword(s):  
Bacillus Thuringiensis ◽  
Batch Culture ◽  
Ph Control ◽  
Fed Batch ◽  
Fed Batch Culture

High-level production of arachidonic acid by fed-batch culture of Mortierella alpina using NH4OH as a nitrogen source and pH control

2005 ◽  
Vol 27 (10) ◽  
pp. 731-735 ◽  
Author(s):  
Byung-Hae Hwang ◽  
Jin-Wook Kim ◽  
Chang-Yeol Park ◽  
Chang-Seo Park ◽  
Yong-Sung Kim ◽  
...  
Keyword(s):  
Arachidonic Acid ◽  
Nitrogen Source ◽  
Batch Culture ◽  
Ph Control ◽  
Mortierella Alpina ◽  
Fed Batch ◽  
Fed Batch Culture ◽  
High Level ◽  
Level Production

High butanol production by Clostridium saccharoperbutylacetonicum N1-4 in fed-batch culture with pH-Stat continuous butyric acid and glucose feeding method

2004 ◽  
Vol 98 (4) ◽  
pp. 263-268 ◽  
Author(s):  
Yukihiro Tashiro ◽  
Katsuhisa Takeda ◽  
Genta Kobayashi ◽  
Kenji Sonomoto ◽  
Ayaaki Ishizaki ◽  
...  
Keyword(s):  
Batch Culture ◽  
Butyric Acid ◽  
Butanol Production ◽  
Fed Batch ◽  
Feeding Method ◽  
Glucose Feeding ◽  
Ph Stat ◽  
Fed Batch Culture

Improved Production of Bacillus thuringiensis by Intermittent Fed-Batch Culture with Total Cell Retention

2010 ◽  
Vol 8 (1) ◽  
Author(s):  
Edwin Habeych ◽  
Andrés F González Barrios ◽  
Alexandre Restrepo-Boland ◽  
Sergio Orduz
Keyword(s):  
Bacillus Thuringiensis ◽  
Batch Culture ◽  
Spodoptera Frugiperda ◽  
Total Cell ◽  
Spore Concentration ◽  
Fed Batch ◽  
Cell Retention ◽  
Filtration System ◽  
Fed Batch Culture ◽  
Flow Filtration

Intermittent fed-batch culture with total cell retention was evaluated during Bacillus thuringiensis serovar. kurstaki fermentations aiming to enhance biomass and spore concentration yields while maintaining toxicity. This method is derived from the already reported intermittent fed-batch culture and utilized a tangential flow filtration system for cell retention. After 4 pulses, we obtained a biomass of 74.36 g·L-1 and this biomass displayed a half lethal concentration towards neonate Spodoptera frugiperda larvae of 40.53 ng·cm-2, and spore concentration of 4.6 x 1014 CFU mL-1. On the other hand, volumetric productivity was increased seven-fold compared to batch fermentation. Interestingly, we are not aware of higher spore concentrations reported to date for B. thuringiensis cultures.

Effect of glucose feeding on the glycosylation quality of antibody produced by a human cell line, F2N78, in fed-batch culture

2014 ◽  
Vol 98 (8) ◽  
pp. 3509-3515 ◽  
Author(s):  
Jin Seok Seo ◽  
Byung Sup Min ◽  
Yeon Jung Kim ◽  
Jong Moon Cho ◽  
Eric Baek ◽  
...  
Keyword(s):  
Cell Line ◽  
Batch Culture ◽  
Human Cell ◽  
Human Cell Line ◽  
Fed Batch ◽  
Glucose Feeding ◽  
Fed Batch Culture ◽  
Effect Of Glucose

Automatic Control Design for Optimal Strategy in Fed-batch Culture with Coupled Feed of Glycerol and Alkali

2010 ◽  
Vol 8 (1) ◽  
Author(s):  
Shan Jiang ◽  
Jianxiong Ye ◽  
Enmin Feng ◽  
Zhilong Xiu
Keyword(s):  
Control System ◽  
Automatic Control ◽  
Batch Culture ◽  
Feeding Strategy ◽  
Nonlinear Dynamical System ◽  
Control Design ◽  
Fed Batch ◽  
Multi Stage ◽  
Fed Batch Culture ◽  
Monitored Control System

In this paper, we study the production of 1,3-propanediol in fed-batch culture with coupled feed of glycerol and alkali. On the basis of the numerical solution to an optimal control problem subjected to a multi-stage nonlinear dynamical system, we propose a realizable optimal feeding strategy. Correspondingly, an automatic control system is designed for the fermenter, which involves the designs of control circuit, software flow control and computer monitored control system. This contribution successfully achieves a goal of combining a mathematically theoretical analysis with an automatic control design in the laboratory.

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