scholarly journals Bulk structure of poly (ethylene glycol)/Titania hybrid system and the evaluation of their influence on apatite growth using simulated body fluid (SBF)

2020 ◽  
pp. 106984
Author(s):  
Shuta Hara ◽  
Jumpei Aisu ◽  
Yu Nishizaki ◽  
Haruki Kato ◽  
Genza Sanae ◽  
...  
Keyword(s):  
Simulated Body Fluid ◽  
Ethylene Glycol ◽  
Hybrid System ◽  
Body Fluid ◽  
Poly Ethylene Glycol ◽  
Bulk Structure ◽  
Poly Ethylene

New hybrid system: Poly(ethylene glycol) hydrogel with covalently bonded pegylated nanotubes

2010 ◽  
Vol 120 (1) ◽  
pp. 124-132 ◽  
Author(s):  
Virginia Saez-Martinez ◽  
Ainara Garcia-Gallastegui ◽  
Carolina Vera ◽  
Beatriz Olalde ◽  
Iratxe Madarieta ◽  
...  
Keyword(s):  
Ethylene Glycol ◽  
Hybrid System ◽  
Poly Ethylene Glycol ◽  
Covalently Bonded ◽  
Poly Ethylene

scholarly journals Laser-textured surface storing a carbon dots/poly(ethylene glycol)/chitosan gel with slow-release lubrication effect

RSC Advances ◽  
2017 ◽  
Vol 7 (35) ◽  
pp. 21600-21606 ◽  
Author(s):  
Hailin Lu ◽  
Shanshan Ren ◽  
Pengpeng Zhang ◽  
Junde Guo ◽  
Jianhui Li ◽  
...  
Keyword(s):  
Ethylene Glycol ◽  
Body Fluid ◽  
Slow Release ◽  
Poor Performance ◽  
Textured Surface ◽  
Poly Ethylene Glycol ◽  
Glycol Chitosan ◽  
Poly Ethylene ◽  
Lubrication Effect ◽  
Chitosan Gel

Arthroplasty presents wear problems because body fluid, as the only lubricant, has poor performance.

PIEZOELECTRIC PROPERTIES OF POLY(3-HYDROXYBUTYRATE-CO-3-HEDROXYBUTYRATE)-CO-POLY(ETHYLENE GLYCOL) PRODUCED BY CONTROLLED MICROBIOLOGICAL BIOSYNTHESIS

2019 ◽  
Vol 10 (10) ◽  
Author(s):  
Anton Bonartsev ◽  
Vera Voinova ◽  
Elizaveta Akoulina ◽  
Andrey Dudun ◽  
Irina Zharkova ◽  
...  
Keyword(s):  
Ethylene Glycol ◽  
Piezoelectric Properties ◽  
Poly Ethylene Glycol ◽  
Poly Ethylene

Thermosensitives hydrogels based on poly (ethylene glycol): I. Synthesis, characterization and release

2007 ◽  
Vol 32 (5) ◽  
pp. 431-446 ◽  
Author(s):  
Tahar Bartil ◽  
Mahmoud Bounekhel ◽  
Cedric Calberg ◽  
Robert Jerome
Keyword(s):  
Ethylene Glycol ◽  
Poly Ethylene Glycol ◽  
Poly Ethylene

Quantifying Heart Valve Interstitial Cell Contractile State Using Highly Tunable Poly(Ethylene Glycol) Hydrogels

2019 ◽  
Author(s):  
Alex Khang ◽  
Andrea Gonzalez Rodriguez ◽  
Megan E. Schroeder ◽  
Jacob Sansom ◽  
Emma Lejeune ◽  
...  
Keyword(s):  
Ethylene Glycol ◽  
Heart Valve ◽  
Interstitial Cell ◽  
Poly Ethylene Glycol ◽  
Contractile State ◽  
Poly Ethylene

Tissue Distribution and Systemic Toxicity Evaluation of Raloxifene Targeted Polymeric Micelles of Poly (Styrene-Maleic Acid)-Poly (Amide- Ether-Ester-Imide)-Poly (Ethylene Glycol) Loaded With Docetaxel in Breast Cancer Bearing Mice

2019 ◽  
Vol 14 (3) ◽  
pp. 280-291 ◽  
Author(s):  
Jaleh Varshosaz ◽  
Farshid Hassanzadeh ◽  
Batool Hashemi-Beni ◽  
Mohsen Minaiyan ◽  
Saeedeh Enteshari
Keyword(s):  
Side Effects ◽  
Antitumor Activity ◽  
Ethylene Glycol ◽  
Tissue Distribution ◽  
Tumor Cells ◽  
Maleic Acid ◽  
Polymeric Micelles ◽  
Poly Ethylene Glycol ◽  
Poly Ethylene ◽  
Ether Ester

Background: Due to the low water solubility of Docetaxel (DTX), it is formulated with ethanol and Tween 80 with lots of side effects. For this reason, special attention has been paid to formulate it in new drug nano-carriers. Objective: The goal of this study was to evaluate the safety, antitumor activity and tissue distribution of the novel synthesized Raloxifene (RA) targeted polymeric micelles. Methods: DTX-loaded RA-targeted polymeric micelles composed of poly(styrene-maleic acid)- poly(amide-ether-ester-imide)-poly(ethylene glycol) (SMA-PAEE-PEG) were prepared and their antitumor activity was studied in MC4-L2 tumor-bearing mice compared with non-targeted micelles and free DTX. Safety of the micelles was studied by Hematoxylin and Eosin (H&E) staining of tumors and major organs of the mice. The drug accumulation in the tumor and major organs was measured by HPLC method. Results: The results showed better tumor growth inhibition and increased survival of mice treated with DTX-loaded in targeted micelles compared to the non-targeted micelles and free DTX. Histopathological studies, H&E staining of tumors and immunohistochemical examination showed the potential of DTX-loaded RA-targeted micelles to inhibit tumor cells proliferation. The higher accumulation of the DTX in the tumor tissue after injection of the micelles compared to the free DTX may indicate the higher uptake of the targeted micelles by the G-Protein-Coupled Estrogen Receptors (GPER). Conclusion: The results indicate that RA-conjugated polymeric micelles may be a strong and effective drug delivery system for DTX therapy and uptake of the drug into tumor cells, and overcome the disadvantages and side effects of conventional DTX.

Sign in / Sign up

Export Citation Format

Share Document