Engineering quaternized chitosan in the 3D bacterial cellulose structure for antibacterial wound dressings

2020 ◽  
Vol 86 ◽  
pp. 106490 ◽  
Author(s):  
Haiyong Ao ◽  
Wenwen Jiang ◽  
Yanjiao Nie ◽  
Chen Zhou ◽  
Jiajia Zong ◽  
...  
Keyword(s):  
Bacterial Cellulose ◽  
Wound Dressings ◽  
Cellulose Structure ◽  
Quaternized Chitosan

scholarly journals Wound Healing Composite Materials of Bacterial Cellulose and Zinc Oxide Nanoparticles with Immobilized Betulin Diphosphate

Nanomaterials ◽  
2021 ◽  
Vol 11 (3) ◽  
pp. 713
Author(s):  
Nina Melnikova ◽  
Alexander Knyazev ◽  
Viktor Nikolskiy ◽  
Peter Peretyagin ◽  
Kseniia Belyaeva ◽  
...  
Keyword(s):  
Wound Healing ◽  
Zinc Oxide ◽  
Bacterial Cellulose ◽  
Zinc Oxide Nanoparticles ◽  
Wound Dressings ◽  
Oxide Nanoparticles ◽  
Burn Wound ◽  
Zno Nps ◽  
Wound Model ◽  
And Oxidative Stress

A design of new nanocomposites of bacterial cellulose (BC) and betulin diphosphate (BDP) pre-impregnated into the surface of zinc oxide nanoparticles (ZnO NPs) for the production of wound dressings is proposed. The sizes of crystalline BC and ZnO NPs (5–25%) corresponded to 5–6 nm and 10–18 nm, respectively (powder X-ray diffractometry (PXRD), Fourier-infrared (FTIR), ultraviolet (UV), atomic absorption (AAS) and photoluminescence (PL) spectroscopies). The biological activity of the wound dressings “BC-ZnO NPs-BDP” was investigated in rats using a burn wound model. Morpho-histological studies have shown that more intensive healing was observed during treatment with hydrophilic nanocomposites than the oleophilic standard (ZnO NPs-BDP oleogel; p < 0.001). Treatment by both hydrophilic and lipophilic agents led to increases in antioxidant enzyme activity (superoxide dismutase (SOD), catalase) in erythrocytes and decreases in the malondialdehyde (MDA) concentration by 7, 10 and 21 days (p < 0.001). The microcirculation index was restored on the 3rd day after burn under treatment with BC-ZnO NPs-BDP wound dressings. The results of effective wound healing with BC-ZnO NPs-BDP nanocomposites can be explained by the synergistic effect of all nanocomposite components, which regulate oxygenation and microcirculation, reducing hypoxia and oxidative stress in a burn wound.

Tailoring bacterial cellulose structure through CRISPR interference‐mediated downregulation of galU in Komagataeibacter xylinus CGMCC 2955

2020 ◽  
Vol 117 (7) ◽  
pp. 2165-2176 ◽  
Author(s):  
Long‐Hui Huang ◽  
Qi‐Jing Liu ◽  
Xue‐Wen Sun ◽  
Xue‐Jing Li ◽  
Miao Liu ◽  
...  
Keyword(s):  
Bacterial Cellulose ◽  
Cellulose Structure ◽  
Crispr Interference ◽  
Komagataeibacter Xylinus

Fabrication of bacterial cellulose-based wound dressings with improved performance by impregnation with alginate

2020 ◽  
Vol 110 ◽  
pp. 110619 ◽  
Author(s):  
Irina Sulaeva ◽  
Hubert Hettegger ◽  
Anna Bergen ◽  
Christian Rohrer ◽  
Mirjana Kostic ◽  
...  
Keyword(s):  
Bacterial Cellulose ◽  
Wound Dressings ◽  
Improved Performance

Capability of Bacterial Cellulose Membrane in Release of Doxycycline

2016 ◽  
Vol 5 (1) ◽  
pp. 44-55 ◽  
Author(s):  
Mohammad Ali Salehi ◽  
Masomeh Jahani Kadusarai ◽  
Mojtaba Akbari Dogolsar
Keyword(s):  
Bacterial Cellulose ◽  
Future Research ◽  
Cellulose Membrane ◽  
Bacterial Product ◽  
Buffer Solution ◽  
Release Process ◽  
Cellulose Structure ◽  
Microbial Product ◽  
Bacterial Cellulose Membrane ◽  
Uv Visible

Bacterial cellulose produced by Gluconacetobacter xylinus is an advantage bacterial product cause of its unique properties, could be used as an ideal dress. The aim of this study was to consider the capability of this biomaterial in release of doxycycline. Proving of this capability provided the outline for production of a dressing containing antibiotic. In this study, bacterial cellulose was synthesized by G.xylinus and loaded from doxycycline then release process was considered in dilute water and buffer phosphate saline. UV-visible spectrophotometry method was applied to measuring the concentration of released drug. Bacterial cellulose structure of chemical was confirmed by Fourier Transform Infrared spectroscopy. Release of doxycycline in dilute water and phosphate saline buffer reach to 73.25% and 94.9%, respectively. Because of more released in buffer solution, peer that process of releasing exhibit exactly results. Results of this study provided the ground for future research on supplying an ideal dressing from this microbial product.

WOUND DRESSINGS BASED ON BACTERIAL CELLULOSE: PREPARATION, PROPERTIES AND USE

2020 ◽  
pp. 94-95
Author(s):  
E. Shishatskaya
Keyword(s):  
Silver Nanoparticles ◽  
Bacterial Cellulose ◽  
Wound Dressings ◽  
Laboratory Animals ◽  
Antibacterial Drugs

Polymer wound dressings based on bacterial cellulose, including those loaded with antibacterial drugs and silver nanoparticles, were produced and comprehensively studied. Regenerative properties of the experimental wound dressings were tested using laboratory animals with model defects of suppurating wounds and third-degree skin burns.

Bacterial Nanocellulose based wound dressings: Current and Future Prospects

2021 ◽  
Vol 27 ◽  
Author(s):  
Hitesh Chopra ◽  
Shweta Gandhi ◽  
Rupesh Kumar Gautam ◽  
Mohammad Amjad Kamal
Keyword(s):  
Wound Healing ◽  
Bacterial Cellulose ◽  
Preparation Method ◽  
Treatment Options ◽  
Antibacterial Properties ◽  
Wound Dressings ◽  
Future Prospects ◽  
Bacterial Nanocellulose

: Although there is a big heap of treatment options available for the wound and burns dressings, improvements in technology are still required. Bacterial cellulose is a polymer derived from the microbiological world and has shown some promising properties that recommend it as a wound healing therapeutic. Moreover, bacterial cellulose can be nanosized to form Bacterial Nanocellulose (BNC), enhancing its properties. Most importantly, in addition to its inherent antibacterial properties, BNC can be used to deliver drugs. This article presents a birds-eye view of the preparation method and applications of BNC based wound dressings.

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