Orientation of poly(vinyl alcohol) nanofiber and crystallites in non-woven electrospun nanofiber mats under uniaxial stretching

Polymer ◽  
2012 ◽  
Vol 53 (21) ◽  
pp. 4702-4708 ◽  
Author(s):  
Takahiro Yano ◽  
Yuji Higaki ◽  
Di Tao ◽  
Daiki Murakami ◽  
Motoyasu Kobayashi ◽  
...  
Keyword(s):  
Vinyl Alcohol ◽  
Poly Vinyl Alcohol ◽  
Electrospun Nanofiber ◽  
Uniaxial Stretching ◽  
Nanofiber Mats

Ciprofloxacin-loaded alginate/poly (vinyl alcohol)/gelatin electrospun nanofiber mats as antibacterial wound dressings

2021 ◽  
pp. 152808372199746
Author(s):  
Tittaya Thairin ◽  
Patcharaporn Wutticharoenmongkol
Keyword(s):  
Weight Loss ◽  
Vinyl Alcohol ◽  
Diffusion Method ◽  
Poly Vinyl Alcohol ◽  
Burst Release ◽  
Electrospun Nanofiber ◽  
Total Immersion ◽  
Water Swelling ◽  
Nanofiber Mats ◽  
And Diffusion

Herein, ciprofloxacin (CIP)-loaded alginate/poly (vinyl alcohol)/gelatin (SPG) (CIP–SPG) nanofiber mats were successfully fabricated by electrospinning. The average fiber diameters of the mats before and after crosslinking were in the range of 190–260 and 385–484 nm, respectively. The chemical integrity of CIP remained intact after encapsulation into the mats. The degree of weight loss and water swelling decreased with an increase in the gelatin content of the electrospun nanofiber mats. A release study was carried out by total immersion and diffusion methods using phosphate buffer as a release medium. Burst release of CIP was observed in case of the total immersion method, while a more sustained release was observed in case of the diffusion method. The maximum amounts of CIP released during total immersion and diffusion were in the range of 70–90% and 72–85%, respectively. For both the total immersion and diffusion methods, the released amounts of CIP decreased and the release slowed down with an increase in the gelatin content; this result is consistent with the weight loss and water swelling values. The Young’s modulus increased, while the tensile strength and strain at break decreased with an increase in the gelatin content. The CIP–SPG nanofiber mats were slightly toxic to L929 mouse fibroblasts as evaluated by indirect cytotoxicity assay. The electrospun CIP–SPG nanofiber mats exhibited excellent antimicrobial activity against Staphylococcus aureus and Escherichia coli. These results reveal that the electrospun CIP–SPG nanofiber mats are potentially promising materials for wound healing applications.

Dual-Charge Nanofiber Mats Made of Chitosan(CS)/Poly(Vinyl Alcohol) (PVA) and Poly-(Acrylic Acid-Co-Maleic Acid) (PAMA)/PVA

2019 ◽  
Vol 819 ◽  
pp. 145-150
Author(s):  
Thapakorn Chareonying ◽  
Junnasir M. Sakilan ◽  
Theerasak Rojanarata ◽  
Prasopchai Patrojanasophon ◽  
Prasert Akkaramongkolporn ◽  
...  
Keyword(s):  
Acrylic Acid ◽  
Maleic Acid ◽  
Vinyl Alcohol ◽  
Electrospinning Process ◽  
Poly Vinyl Alcohol ◽  
Water Capacity ◽  
Ft Ir ◽  
Nanofiber Mats ◽  
Positively Charged ◽  
Poly Acrylic Acid

Nanofibers have been widely used for tissue engineering. Using charged polymers for the preparation of nanofibers can be useful for the loading of substances or macromolecules. Dual charge nanofiber mats are expected to be able to immobilize both positively charged and negatively charged substances in one versatile nanofiber mat. The purpose of this study was to prepare and characterize dual-charge nanofibers generated from poly (vinyl alcohol) (PVA)/poly-(acrylic acid-co-maleic acid) (PAMA) and chitosan (CS)/PVA. The polymer solutions of PAMA/PVA (1:1.63 w/w) and CS/PVA (1:2.33 w/w) were electrospun to form the nanofibers using dual-jet electrospinning process. The obtained dual-charge nanofibers were thermally crosslinked by leaving the nanofibers in the oven at 110-130 °C for 0.5, 1, 3, 5 h. The appearance of the nanofiber mat was characterized by a scanning electron microscope (SEM), and the diameter of nanofibers were determined by an image analysis software (J-micro vision®). The percentage water insolubilization and FT-IR spectra were also determined. The dual-size nanofiber mats with smooth and bead-free fibers were obtained. The diameter of the PAMA/PVA and CS/PVA fibers was 574.54 ± 142.98 nm and 225.69 ± 41.92 nm, respectively. The desirable temperature and time for the crosslink of the dual-charge nanofiber mats was 130 °C for 1 h which could provide a high insolubilization with water capacity of 93.22 ± 2.23%.

Preparation and characterization of poly(vinyl alcohol) nanofiber mats crosslinked with blocked isocyanate prepolymer

2010 ◽  
Vol 59 (12) ◽  
pp. 1683-1689 ◽  
Author(s):  
Ji-Hui Lee ◽  
Un-Soo Lee ◽  
Kwang-Un Jeong ◽  
Yun-A Seo ◽  
Soo-Jin Park ◽  
...  
Keyword(s):  
Vinyl Alcohol ◽  
Poly Vinyl Alcohol ◽  
Blocked Isocyanate ◽  
Nanofiber Mats ◽  
Isocyanate Prepolymer

scholarly journals Characterization, Antibacterial and Anti-Inflammatory Activities of Electrospun poly (vinyl alcohol) (PVA) Containing Aquilaria malaccencis Leaf Extract (ALEX) Nanofibers

2020 ◽  
Vol 9 (3) ◽  
pp. 541-548
Keyword(s):  
Vinyl Alcohol ◽  
Wound Dressing ◽  
Leaf Extract ◽  
Vibrio Vulnificus ◽  
Electrospun Nanofibers ◽  
Poly Vinyl Alcohol ◽  
Scanning Calorimetry ◽  
Swelling Degree ◽  
Anti Inflammatory ◽  
Nanofiber Mats

Plant-based electrospun nanofibers are widely fabricated as wound dressing in recent years primarily due to the presence of bioactive compounds which can facilitate the wound healing effects. In this study, poly(vinyl alcohol) (PVA) fibre mats containing Aquilaria malaccensis leaf extract (ALEX) [5, 10 and 15 %(w/w)] were fabricated by electrospinning method as potential wound dressing material. The nanofibers were uniform, beadless and randomly oriented with average diameters ranged between 195.27 – 281.20 nm. The presence of ALEX in the PVA nanofibers were evaluated by Attenuated total reflectance-Fourier transform infrared spectroscopy (ATR-FTIR) and differential scanning calorimetry (DSC). The mechanical properties, swelling degree and weight loss of nanofiber mats were also determined. ALEX was rapidly released from the ALEX-loaded PVA nanofibers in the first 12 hours and increased gradually afterwards. The released rate of ALEX was dependent on the ALEX content in the PVA nanofibers. This result is also contributed by the swelling degree and porosity of the nanofibers where the results were found to be between 241.66 – 305.86% and 64.53 – 30.81%, respectively. Meanwhile, the tensile stress and maximum elongation at break for all electrospun nanofiber mats were in the range of 8.56 – 2.68 MPa and 205.94 – 166.31%, respectively. The nanofiber mats inhibited growth of Escherichia coli, Vibrio vulnificus, Bacillus subtilis and Staphylococcus aureus with zone of inhibition of 7.5 - 15.0 mm for gram positive bacteria and 6.1 - 11.7 mm for gram negative bacteria. ALEX-loaded PVA nanofibers also showed potent anti-inflammatory activity against lipoxygenase with percentage of inhibition between 80.887 – 86.977%. Taken together, the results of this study suggest that ALEX-loaded PVA nanofibers have the desired properties of bioactive wound dressing.

scholarly journals Effect of Moisture on Electrospun Nanofiber Composites of Poly(vinyl alcohol) and Cellulose Nanocrystals

2010 ◽  
Vol 11 (9) ◽  
pp. 2471-2477 ◽  
Author(s):  
Maria S. Peresin ◽  
Youssef Habibi ◽  
Arja-Helena Vesterinen ◽  
Orlando J. Rojas ◽  
Joel J. Pawlak ◽  
...  
Keyword(s):  
Cellulose Nanocrystals ◽  
Vinyl Alcohol ◽  
Poly Vinyl Alcohol ◽  
Electrospun Nanofiber ◽  
Effect Of Moisture

Effect of Poly(vinyl alcohol)/Chitosan Ratio on Electrospun-Nanofiber Morphologies

2012 ◽  
Vol 463-464 ◽  
pp. 734-738 ◽  
Author(s):  
Tongsai Jamnongkan ◽  
Amnuay Wattanakornsiri ◽  
P. Pungboon Pansila ◽  
Claudio Migliaresi ◽  
Supranee Kaewpirom
Keyword(s):  
Electron Microscopy ◽  
Scanning Electron Microscopy ◽  
Vinyl Alcohol ◽  
Weight Ratio ◽  
Electrospun Nanofibers ◽  
Poly Vinyl Alcohol ◽  
Electrospun Nanofiber ◽  
Electrospinning Method ◽  
Chitosan Content ◽  
Scanning Electron

Series of poly (vinyl alcohol)/chitosan (PVA/CS) electrospun nanofibers with different weight ratio of PVA and CS were fabricated by electrospinning method. The surface morphology, diameter, and structure of electrospun nanofibers were investigated by scanning electron microscopy (SEM). As a result of PVA and CS composition measurements, the electrospun nanofibers morphologies were mainly affected by weight ratio of the polymer solution. When increasing the chitosan content in the blend solution, the electrospun nanofibers could hardly form. This result indicates that the electrospun nanofiber formation is enhanced by chitosan content.

Physical characteristics of poly (vinyl alcohol) solutions in relation to electrospun nanofiber formation

2013 ◽  
Vol 49 (2) ◽  
pp. 290-298 ◽  
Author(s):  
Romana Rošic ◽  
Jan Pelipenko ◽  
Julijana Kristl ◽  
Petra Kocbek ◽  
Marija Bešter-Rogač ◽  
...  
Keyword(s):  
Vinyl Alcohol ◽  
Physical Characteristics ◽  
Poly Vinyl Alcohol ◽  
Electrospun Nanofiber
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