Preparation of magnetite and tumor dual-targeting hollow polymer microspheres with pH-sensitivity for anticancer drug-carriers

Polymer ◽  
2010 ◽  
Vol 51 (12) ◽  
pp. 2533-2539 ◽  
Author(s):  
Xiaoying Yang ◽  
Lei Chen ◽  
Bin Han ◽  
Xinlin Yang ◽  
Hongquan Duan
Keyword(s):  
Anticancer Drug ◽  
Drug Carriers ◽  
Ph Sensitivity ◽  
Polymer Microspheres ◽  
Dual Targeting

Multi-functionalized graphene oxide based anticancer drug-carrier with dual-targeting function and pH-sensitivity

2011 ◽  
Vol 21 (10) ◽  
pp. 3448-3454 ◽  
Author(s):  
Xiaoying Yang ◽  
Yinsong Wang ◽  
Xin Huang ◽  
Yanfeng Ma ◽  
Yi Huang ◽  
...  
Keyword(s):  
Graphene Oxide ◽  
Anticancer Drug ◽  
Drug Carrier ◽  
Ph Sensitivity ◽  
Functionalized Graphene ◽  
Functionalized Graphene Oxide ◽  
Dual Targeting

scholarly journals Novel multi-responsive polymer magnetic microgels with folate or methyltetrahydrofolate ligand as anticancer drug carriers

RSC Advances ◽  
2017 ◽  
Vol 7 (17) ◽  
pp. 10333-10344 ◽  
Author(s):  
Yunli Hu ◽  
Weijun Liu ◽  
Fanhong Wu
Keyword(s):  
Cancer Cells ◽  
Anticancer Drug ◽  
Cellular Uptake ◽  
Hela Cells ◽  
Targeted Delivery ◽  
Drug Carriers ◽  
Ph Sensitivity ◽  
Responsive Polymer ◽  
L02 Cells

MP-PNAAEF or MP-PNAAEM microgels exhibiting good thermo- and pH-sensitivity have been prepared for targeted delivery to FR(+) cancer cells. The DOX-loaded microgels showed higher cellular uptake by the Hela cells, but not by the L02 cells.

Advances in Nanoparticles as Anticancer Drug Delivery Vector: Need of this Century

2020 ◽  
Vol 26 (15) ◽  
pp. 1637-1649 ◽  
Author(s):  
Imran Ali ◽  
Sofi D. Mukhtar ◽  
Heyam S. Ali ◽  
Marcus T. Scotti ◽  
Luciana Scotti
Keyword(s):  
Drug Delivery ◽  
Anticancer Drug ◽  
Medical Science ◽  
Drug Carriers ◽  
Anticancer Drug Delivery ◽  
Ph Values ◽  
Delivery Vector ◽  
Future Challenges ◽  
Smart Drug ◽  
Smart Drug Delivery

Background: Nanotechnology has contributed a great deal to the field of medical science. Smart drugdelivery vectors, combined with stimuli-based characteristics, are becoming increasingly important. The use of external and internal stimulating factors can have enormous benefits and increase the targeting efficiency of nanotechnology platforms. The pH values of tumor vascular tissues are acidic in nature, allowing the improved targeting of anticancer drug payloads using drug-delivery vectors. Nanopolymers are smart drug-delivery vectors that have recently been developed and recommended for use by scientists because of their potential targeting capabilities, non-toxicity and biocompatibility, and make them ideal nanocarriers for personalized drug delivery. Method: The present review article provides an overview of current advances in the use of nanoparticles (NPs) as anticancer drug-delivery vectors. Results: This article reviews the molecular basis for the use of NPs in medicine, including personalized medicine, personalized therapy, emerging vistas in anticancer therapy, nanopolymer targeting, passive and active targeting transports, pH-responsive drug carriers, biological barriers, computer-aided drug design, future challenges and perspectives, biodegradability and safety. Conclusions: This article will benefit academia, researchers, clinicians, and government authorities by providing a basis for further research advancements.

scholarly journals Microbubble generation in phase-shift nanoemulsions used as anticancer drug carriers

2009 ◽  
Vol 1 (1-2) ◽  
pp. 31-39 ◽  
Author(s):  
N. Y. Rapoport ◽  
A. L. Efros ◽  
D. A. Christensen ◽  
A. M. Kennedy ◽  
K.-H. Nam
Keyword(s):  
Phase Shift ◽  
Anticancer Drug ◽  
Drug Carriers

Stimuli-Sensitive Polymeric Micelles as Anticancer Drug Carriers

2006 ◽  
Vol 6 (6) ◽  
pp. 525-535 ◽  
Author(s):  
Kun Na ◽  
Vijay Sethuraman ◽  
You Han Bae ◽  
Vijay Sethuraman
Keyword(s):  
Anticancer Drug ◽  
Polymeric Micelles ◽  
Drug Carriers ◽  
Stimuli Sensitive

Biocompatible Zr-based nanoscale MOFs coated with modified poly(ε-caprolactone) as anticancer drug carriers

2016 ◽  
Vol 509 (1-2) ◽  
pp. 208-218 ◽  
Author(s):  
Maria Filippousi ◽  
Stuart Turner ◽  
Karen Leus ◽  
Panoraia I. Siafaka ◽  
Eirini D. Tseligka ◽  
...  
Keyword(s):  
Anticancer Drug ◽  
Drug Carriers

Naturally derived DNA nanogels as pH- and glutathione-triggered anticancer drug carriers

2020 ◽  
Vol 114 ◽  
pp. 111025 ◽  
Author(s):  
Yu-Fon Chen ◽  
Ming-Wei Hsu ◽  
Yu-Chu Su ◽  
Ho-Min Chang ◽  
Chien-Hsiang Chang ◽  
...  
Keyword(s):  
Anticancer Drug ◽  
Drug Carriers

A dual targeting cyclodextrin/gold nanoparticle conjugate as a scaffold for solubilization and delivery of paclitaxel

RSC Advances ◽  
2015 ◽  
Vol 5 (12) ◽  
pp. 8938-8941 ◽  
Author(s):  
Yong Chen ◽  
Nan Li ◽  
Yang Yang ◽  
Yu Liu
Keyword(s):  
Gold Nanoparticle ◽  
Anticancer Drug ◽  
Dual Targeting

A cyclodextrin/gold nanoparticle conjugate was constructed as a dual targeting scaffold for solubilization and delivery of anticancer drug paclitaxel.

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