The mechanism of 60Co γ-ray radiation induced interfacial redox reaction in inverse emulsion and its application in the synthesis of polymer microcapsules

Polymer ◽  
2007 ◽  
Vol 48 (1) ◽  
pp. 150-157 ◽  
Author(s):  
Linyong Song ◽  
Mozhen Wang ◽  
Yuanhua Cong ◽  
Weijun Liu ◽  
Xuewu Ge ◽  
...  
2021 ◽  
Author(s):  
Wei Hu ◽  
Jiawu Liang ◽  
Song Liao ◽  
Zhidong Zhao ◽  
Yuxing Wang ◽  
...  

Abstract Background Ionizing radiation poses a challenge to the healing of bone defects. Radiation therapy and accidental exposure to gamma-ray (γ-ray) radiation inhibit bone formation and increase the risk of fractures. Cortical bone-derived stem cells (CBSCs) are essential for osteogenic lineages, bone maintenance, and repair. This study aimed to investigate the effects of melatonin on postradiation CBSCs and bone defects. Methods CBSCs were extracted from C57/BL6 mice and were identified by flow cytometry. The effects of exogenous melatonin on the self-renewal and osteogenic capacity of postradiation CBSCs were detected in vitro. The underlying mechanisms in terms of genomic stability, apoptosis and oxidative stress-related signaling were further analyzed by western blotting, flow cytometry and immunofluorescence. Finally, the effects of melatonin on healing in postradiation bone defects were evaluated in vivo by micro-CT and immunohistochemical analysis. Results The radiation-induced reduced self-renewal and osteogenic capacity were partially reversed in postradiation CBSCs treated with melatonin. Melatonin maintained the genomic stability and apoptosis of postradiation CBSCs, and intracellular oxidative stress was decreased significantly while antioxidant-related enzymes were enhanced. Western blotting verified the anti-inflammatory effect of melatonin by downregulating the levels of IL-6 and TNF-α via extracellular regulated kinase (ERK)/nuclear factor erythroid 2-related factor 2 (NRF2)/heme oxygenase 1 (HO-1) signaling, distinct from its antioxidant effect via NRF2 signaling. In vivo experiments demonstrated that the newly formed bone in the melatonin plus Matrigel group had higher trabecular bone volume per tissue volume (BV/TV) and bone mineral density (BMD) values, and lower levels of IL-6 and TNF-α than those in the irradiation and the Matrigel groups. Conclusions This study suggested the potential of melatonin to protect CBSCs against γ-ray radiation and to assist the healing of postradiation bone defects.


2010 ◽  
Vol 31 (4) ◽  
pp. 910-914 ◽  
Author(s):  
Sang-Wook Kim ◽  
Bob-Jin Kwon ◽  
Jeong-Hoon Park ◽  
Min-Goo Hur ◽  
Seung-Dae Yang ◽  
...  

2008 ◽  
Vol 74 (3) ◽  
pp. 498-503 ◽  
Author(s):  
Min Wang ◽  
Ling Xu ◽  
Maolin Zhai ◽  
Jing Peng ◽  
Jiuqiang Li ◽  
...  

2010 ◽  
Vol 150-151 ◽  
pp. 1764-1767 ◽  
Author(s):  
Jun Fu Wei ◽  
Kong Yin Zhao ◽  
Huan Zhang ◽  
Xiao Lei Wang ◽  
Li Chen

A weak acid cation exchange fiber was prepared by γ-ray pre-radiation induced grafting of acrylic acid (AA) onto polypropylene (PP) non-woven without removal of the polymerization inhibitor in acrylic acid. The factors influenced the grafting degree were discussed, such as radiation dose, initiator concentration, monomer concentration, storage time and bath ratio. It is found that the initiator 2, 2'-Azobisisobutyronitrile (AIBN) was necessary for the increased grafting of AA without removing the inhibitor in AA.


2015 ◽  
Vol 42 ◽  
pp. 251-255 ◽  
Author(s):  
Jing Zhang ◽  
Abu Zayed Mohammad Saliqur Rahman ◽  
Yuxiao Li ◽  
Jing Yang ◽  
Yaru Wu ◽  
...  

Author(s):  
John Warman ◽  
Matthijs deHaas ◽  
Leonard Luthjens ◽  
Antonia Denkova ◽  
Tiantian Yao

Abstract: We review the development and application of an organic polymer-gel capable of producing fixed, three-dimensional fluorescent images of complex radiation fields. The gel consists for more than 99% of γ-ray-polymerized (~15% conversion) tertiary-butyl acrylate (TBA) containing ~100 ppm of a fluorogenic compound, e.g. maleimido-pyrene (MPy). The radio-fluorogenic effect depends on copolymerization of the MPy into growing chains of TBA on radiation-induced polymerization. This converts the maleimido residue, which quenches the pyrene fluorescence, into a succinimido moeity (SPy), which doesn't. The intensity of the fluorescence is proportional to the yield of free-radicals formed and hence to the local dose deposited. Because the SPy moieties are built into the cross-linked polymer matrix the image is fixed. The method of preparing the gel and imaging the radiation-induced fluorescence are presented and discussed. The effect is illustrated with fluorescent images of the energy deposited in the gel by beams of X-rays, electrons and protons as well as a radioactive isotope.


2020 ◽  
Vol 8 (18) ◽  
pp. 9109-9120 ◽  
Author(s):  
Zhiwen Jiang ◽  
Wengang Zhu ◽  
Guoqing Xu ◽  
Xiangjianfei Xu ◽  
Mozhen Wang ◽  
...  

Ni-nanoparticles-bound BNNS with special catalytic property can be one-step fabricated by “a novel radiation-induced reduction-exfoliation” method, i.e., Ni2+-intercalated h-BN crystals can be exfoliated in alcohol/water medium under γ-ray radiation.


Sign in / Sign up

Export Citation Format

Share Document