Mixed-ligand ruthenium(II) complexes capable of hydrogen-bonding interactions with DNA: DNA binding, nuclease activity, cytotoxicity, and topoisomerase inhibition

Polyhedron ◽  
2017 ◽  
Vol 137 ◽  
pp. 34-42 ◽  
Author(s):  
Naho Iizuka ◽  
Misaki Nakai ◽  
Yasuo Nakabayashi
Keyword(s):  
Hydrogen Bonding ◽  
Dna Binding ◽  
Nuclease Activity ◽  
Mixed Ligand ◽  
Hydrogen Bonding Interactions ◽  
Topoisomerase Inhibition

A family of mixed-ligand oxidovanadium(v) complexes with aroylhydrazone ligands: a combined experimental and computational study on the electronic effects of para substituents of hydrazone ligands on the electronic properties, DNA binding and nuclease activities

RSC Advances ◽  
2015 ◽  
Vol 5 (112) ◽  
pp. 92456-92472 ◽  
Author(s):  
Debashis Patra ◽  
Nirmalendu Biswas ◽  
Bhavini Kumari ◽  
Prolay Das ◽  
Nayim Sepay ◽  
...  
Keyword(s):  
Dna Binding ◽  
Electronic Properties ◽  
Computational Study ◽  
Nuclease Activity ◽  
Mixed Ligand ◽  
Electronic Effects ◽  
Binding Ability ◽  
Marked Influence ◽  
Hydrazone Ligands

Substituents at 5-position in the acetophenone ring of the hydrazone ligands in a family of mixed-ligand oxidovanadium(v) complexes show marked influence on the electronic properties, DNA binding ability and nuclease activity.

Fluorescent mixed ligand copper(ii) complexes of anthracene-appended Schiff bases: studies on DNA binding, nuclease activity and cytotoxicity

2015 ◽  
Vol 44 (26) ◽  
pp. 11997-12010 ◽  
Author(s):  
Paramasivam Jaividhya ◽  
Mani Ganeshpandian ◽  
Rajkumar Dhivya ◽  
Mohammad Abdulkadher Akbarsha ◽  
Mallayan Palaniandavar
Keyword(s):  
Dna Binding ◽  
Schiff Bases ◽  
Nuclease Activity ◽  
Mixed Ligand ◽  
Base Pairs ◽  
Dna Base ◽  
Dna Base Pairs

While the phen of [Cu(L1–L5)(phen)(ACN)]2+ partially inserts into DNA base pairs the anthracenyl moiety of L1–L5 interacts with DNA hydrophobically.

scholarly journals Structures of the hydrate and dihydrate forms of the DNA-binding radioprotector methylproamine

2018 ◽  
Vol 74 (12) ◽  
pp. 1903-1907
Author(s):  
Jonathan Michael White ◽  
Samuel Charles Brydon ◽  
Thomas Fellowes
Keyword(s):  
Hydrogen Bonding ◽  
Dna Binding ◽  
Crystal Packing ◽  
Three Dimensional ◽  
Two Dimensional ◽  
Space Groups ◽  
Hydrogen Bonding Interactions ◽  
Tautomeric Forms ◽  
Hydrogen Bonded

Methyl proamine {N,N,3-trimethyl-4-[6-(4-methylpiperazin-1-yl)-1H,3′H-[2,5′-bibenzo[d]imidazol]-2′-yl]aniline}, C28H35N7O2, crystallized as both a dihydrate, C28H31N7·2H2O, and monohydrate, C28H31N7·H2O, form from water in the presence of β-cyclodextrin, in the P21/c and P21/n space groups, respectively. The two structures adopt different conformations and tautomeric forms as a result of the differing crystal packing as dictated by hydrogen-bonding interactions. The dihydrate crystallizes as a three-dimensional hydrogen-bonded network, while the monohydrate crystallizes as a two-dimensional hydrogen-bonded network.

Theoretical study of hydrogen bonding interactions in substituted nitroxide radicals

2021 ◽  
Author(s):  
Thufail M. Ismail ◽  
Neetha Mohan ◽  
P. K. Sajith
Keyword(s):  
Hydrogen Bonding ◽  
Interaction Energy ◽  
Electrostatic Potential ◽  
Molecular Electrostatic Potential ◽  
Theoretical Study ◽  
Nitroxide Radicals ◽  
Hydrogen Bonding Interactions ◽  
Bonded Complexes ◽  
Hydrogen Bonded

Interaction energy (Eint) of hydrogen bonded complexes of nitroxide radicals can be assessed in terms of the deepest minimum of molecular electrostatic potential (Vmin).

scholarly journals Circular linkage of intramolecular multi-hydrogen bonding frameworks through nucleophilic substitutions of β-dicarbonyls onto cyanuric chloride and subsequent tautomerisation

RSC Advances ◽  
2020 ◽  
Vol 10 (64) ◽  
pp. 39033-39036
Author(s):  
Ayano Awatani ◽  
Masaaki Suzuki
Keyword(s):  
Hydrogen Bonding ◽  
Cyanuric Chloride ◽  
Nucleophilic Substitutions ◽  
Hydrogen Bonding Interactions ◽  
Triazine Derivatives

Triply β-dicarbonyl-embedded 1,3,5-triazine derivatives result in formation of circular linkage of resonance-assisted hydrogen bonding interactions, which can be regarded as well-delocalized resonance hybrids.

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