scholarly journals Synthesis, spectral characterization and in vitro microbiological evaluation of novel glyoxal, biacetyl and benzil bis-hydrazone macrocyclic Schiff bases and their Co(II), Ni(II) and Cu(II) complexes

Polyhedron ◽  
2011 ◽  
Vol 30 (9) ◽  
pp. 1507-1515 ◽  
Author(s):  
B. Lakshmi ◽  
Prakash Gouda Avaji ◽  
K.N. Shivananda ◽  
Praveen Nagella ◽  
S.H. Manohar ◽  
...  
Keyword(s):  
Schiff Bases ◽  
Spectral Characterization

Various coordination modes of new coumarin Schiff bases toward Cobalt (III) ion: Synthesis, spectral characterization, in vitro cytotoxic activity, and investigation of apoptosis

2021 ◽  
Author(s):  
Kalaiarasi Giriraj ◽  
Mohamed Subarkhan Mohamed Kasim ◽  
Keerthana Balasubramaniam ◽  
Sathiya Kamatchi Thangavel ◽  
Janani Venkatesan ◽  
...  
Keyword(s):  
Cytotoxic Activity ◽  
Schiff Bases ◽  
Spectral Characterization ◽  
Coordination Modes

scholarly journals Synthesis and Activity of New Schiff Bases of Furocoumarin

2020 ◽  
Vol 26 (1) ◽  
pp. 176-184
Author(s):  
Huijun Xie ◽  
Chao Niu ◽  
Zeyang Chao ◽  
Nuramina Mamat ◽  
Haji Akber Aisa
Keyword(s):  
Animal Models ◽  
Amphotericin B ◽  
Molecular Mechanism ◽  
Schiff Bases ◽  
Positive Control ◽  
Excellent Performance ◽  
Activation Rate ◽  
Antibacterial Spectrum ◽  
Better Than

AbstractFurocoumarins, such as 8-MOP, are the most common medications used to relieve the symptoms of vitiligo clinically. Some furocoumarins also showed excellent performance in an anti-bacterial assay. This paper describes the synthesis of a series of novel Schiff bases (6a-6k), and their promotion in melanogenesis and anti-bacterial properties were studied in vitro.The pigment production of B16 cells and bacterial inhibition ring assay were applied for the bioactivity of 6a-6k. According to the results, a stronger promotion on pigment content was observed, when six compounds co-cultured with cells, compared with positive control (8-MOP). Significantly, compound 6k (237%) as the most active was found to increase the amount of melanin more than 1.7 times compared with 8-MOP activation rate (136%). All the compounds could moderately retard C. albicans growth. Interestingly, aldehyde 5, which possessed a broader antibacterial spectrum, showed the highest inhibition against C. albicans as well and much better than the positive control (Amphotericin B).Studies of 6k in animal models of vitiligo and related molecular mechanism are presently under way, with the aim of discovering an anti-vitiligo leading compound.

Characterization of bis‐Schiff bases synthesized using ZnFe 2 O 4 nanoparticles as catalyst, and examination of their antibacterial and in vitro cytotoxic properties

2020 ◽  
Vol 34 (4) ◽  
Author(s):  
Hamed Maaref ◽  
Enayatollah Sheikhhosseini ◽  
Mohammad Mehdi Foroughi ◽  
Mohammad Reza Akhgar ◽  
Shohreh Jahani
Keyword(s):  
Schiff Bases
Sign in / Sign up

Export Citation Format

Share Document