Docosahexaenoic acid supplementation modifies fatty acid incorporation in tissues and prevents hypoxia induced-atherosclerosis progression in apolipoprotein-E deficient mice

2014 ◽  
Vol 91 (4) ◽  
pp. 111-117 ◽  
Author(s):  
Laetitia Van Noolen ◽  
Magnus Bäck ◽  
Claire Arnaud ◽  
Amandine Rey ◽  
Marcelo H. Petri ◽  
...  
Keyword(s):  
Fatty Acid ◽  
Docosahexaenoic Acid ◽  
Apolipoprotein E ◽  
Acid Supplementation ◽  
Atherosclerosis Progression ◽  
Acid Incorporation ◽  
Fatty Acid Incorporation ◽  
Deficient Mice

Palmitoleic acid (n-7) increases white adipocyte lipolysis and lipase content in a PPARα-dependent manner

2013 ◽  
Vol 305 (9) ◽  
pp. E1093-E1102 ◽  
Author(s):  
Andressa Bolsoni-Lopes ◽  
William T. Festuccia ◽  
Talita S. M. Farias ◽  
Patricia Chimin ◽  
Francisco L. Torres-Leal ◽  
...  
Keyword(s):  
Fatty Acid ◽  
Palmitoleic Acid ◽  
Whole Body ◽  
Mrna Levels ◽  
Dependent Manner ◽  
Wild Type ◽  
Acid Incorporation ◽  
Gene And Protein Expression ◽  
Fatty Acid Incorporation ◽  
Deficient Mice

We investigated whether palmitoleic acid, a fatty acid that enhances whole body glucose disposal and suppresses hepatic steatosis, modulates triacylglycerol (TAG) metabolism in adipocytes. For this, both differentiated 3T3-L1 cells treated with either palmitoleic acid (16:1n7, 200 μM) or palmitic acid (16:0, 200 μM) for 24 h and primary adipocytes from wild-type or PPARα-deficient mice treated with 16:1n7 (300 mg·kg−1·day−1) or oleic acid (18:1n9, 300 mg·kg−1·day−1) by gavage for 10 days were evaluated for lipolysis, TAG, and glycerol 3-phosphate synthesis and gene and protein expression profile. Treatment of differentiated 3T3-L1 cells with 16:1n7, but not 16:0, increased basal and isoproterenol-stimulated lipolysis, mRNA levels of adipose triglyceride lipase (ATGL) and hormone-sensitive lipase (HSL) and protein content of ATGL and pSer660-HSL. Such increase in lipolysis induced by 16:1n7, which can be prevented by pharmacological inhibition of PPARα, was associated with higher rates of PPARα binding to DNA. In contrast to lipolysis, both 16:1n7 and 16:0 increased fatty acid incorporation into TAG and glycerol 3-phosphate synthesis from glucose without affecting glyceroneogenesis and glycerokinase expression. Corroborating in vitro findings, treatment of wild-type but not PPARα-deficient mice with 16:1n7 increased primary adipocyte basal and stimulated lipolysis and ATGL and HSL mRNA levels. In contrast to lipolysis, however, 16:1n7 treatment increased fatty acid incorporation into TAG and glycerol 3-phosphate synthesis from glucose in both wild-type and PPARα-deficient mice. In conclusion, palmitoleic acid increases adipocyte lipolysis and lipases by a mechanism that requires a functional PPARα.

Effects of chronic beta-amyloid treatment on fatty acid incorporation into rat brain

1996 ◽  
Vol 17 (2) ◽  
pp. 301-309 ◽  
Author(s):  
Sheryl K. Brining ◽  
Collins R. Jones ◽  
Michael C.J. Chang
Keyword(s):  
Fatty Acid ◽  
Rat Brain ◽  
Beta Amyloid ◽  
Acid Incorporation ◽  
Fatty Acid Incorporation

Docosahexaenoic acid supplementation in pregnancy alters placental fatty acid composition

Placenta ◽  
2014 ◽  
Vol 35 (9) ◽  
pp. A70 ◽  
Author(s):  
Theresa L. Powell ◽  
Christiane Meireles ◽  
Vanessa I. Ramirez ◽  
Evelyn Miller ◽  
Kevin W. Hakala ◽  
...  
Keyword(s):  
Fatty Acid Composition ◽  
Fatty Acid ◽  
Docosahexaenoic Acid ◽  
Acid Composition ◽  
Acid Supplementation ◽  
In Pregnancy

scholarly journals Enriching Artemia nauplii with selenium from different sources and interactions with essential fatty acid incorporation

Aquaculture ◽  
2020 ◽  
Vol 520 ◽  
pp. 734677 ◽  
Author(s):  
Thomas Cavrois-Rogacki ◽  
Andrew Rolland ◽  
Hervé Migaud ◽  
Andrew Davie ◽  
Oscar Monroig
Keyword(s):  
Fatty Acid ◽  
Essential Fatty Acid ◽  
Artemia Nauplii ◽  
Acid Incorporation ◽  
Fatty Acid Incorporation ◽  
Different Sources

scholarly journals Permissive Fatty Acid Incorporation Promotes Staphylococcal Adaptation to FASII Antibiotics in Host Environments

Cell Reports ◽  
2019 ◽  
Vol 29 (12) ◽  
pp. 3974-3982.e4 ◽  
Author(s):  
Gérald Kénanian ◽  
Claire Morvan ◽  
Antonin Weckel ◽  
Amit Pathania ◽  
Jamila Anba-Mondoloni ◽  
...  
Keyword(s):  
Fatty Acid ◽  
Acid Incorporation ◽  
Fatty Acid Incorporation
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