Polyketides from the endolichenic fungus Eupenicillium javanicum and their anti-inflammatory activities

2020 ◽  
Vol 170 ◽  
pp. 112191 ◽  
Author(s):  
Ke Xu ◽  
Gang Li ◽  
Rongxiu Zhu ◽  
Fei Xie ◽  
Yuelan Li ◽  
...  
Keyword(s):  
Endolichenic Fungus ◽  
Anti Inflammatory

Anti-inflammatory phomalichenones from an endolichenic fungus Phoma sp.

2018 ◽  
Vol 71 (8) ◽  
pp. 753-756 ◽  
Author(s):  
Jong Won Kim ◽  
Wonmin Ko ◽  
Eun Kim ◽  
Gil Soo Kim ◽  
Gwi Ja Hwang ◽  
...  
Keyword(s):  
Endolichenic Fungus ◽  
Anti Inflammatory

scholarly journals Identification of Novel Bioactive Compounds, Neurosporalol 1 and 2 from an Endolichenic Fungus, Neurospora ugadawe Inhabited in the Lichen Host, Graphis tsunodae Zahlbr. from Mangrove Ecosystem in Puttalam Lagoon, Sri Lanka

2021 ◽  
Vol 33 (6) ◽  
pp. 1425-1432
Author(s):  
H.A.K. Maduranga ◽  
W.R.H. Weerasinghe ◽  
R.N. Attanayake ◽  
S. Santhirasegaram ◽  
C.D. Shevkar ◽  
...  
Keyword(s):  
Sri Lanka ◽  
Secondary Metabolites ◽  
Mangrove Ecosystem ◽  
Positive Control ◽  
Mangrove Ecosystems ◽  
Pure Compounds ◽  
Endolichenic Fungus ◽  
Endolichenic Fungi ◽  
Anti Inflammatory ◽  
Promising Source

Endolichenic fungi (ELF) have been recognized as a promising source of bioactive secondary metabolites. Sri Lanka, a biodiversity hotspot, harbours a remarkable diversity in mangrove ecosystems. In the present study, endolichenic fungi obtained from mangrove lichens of Puttalam lagoon were studied for their secondary metabolites. An endolichenic fungus, Neurospora ugadawe, isolated from the lichen host Graphis tsunodae Zahlbr. was identified up to the species level. Secondary metabolites of N. ugadawe were extracted into ethyl acetate and crude extract showed promising antioxidant and anti-inflammatory activities. Bioassay guided separation on silica gel column chromatography and preparative TLC were performed to isolate the bioactive pure compounds. Two novel bioactive pure compounds were identified as Neurosporalol 1 and Neurosporalol 2. Neurosporalol 1 showed the highest antioxidant activity compared with the positive control BHT. Further, this compound showed very low anti-inflammatory activity compared to that of the positive control aspirin. Neurosporalol 2 showed comparable antioxidant and moderate anti-inflammatory activities.

758: Inflammatory and Anti-Inflammatory Regulators alter Levels of an Inhibitor of Apoptosis (IAP), Survivin, in T-24 Bladder Cancer Cells

2007 ◽  
Vol 177 (4S) ◽  
pp. 254-254
Author(s):  
Justin J. Cohen ◽  
Bayan T. Takizawa ◽  
Hristos Z. Kaimkliotis ◽  
David J. Rosenberg ◽  
Marcia A. Wheeler ◽  
...  
Keyword(s):  
Bladder Cancer ◽  
Cancer Cells ◽  
Inhibitor Of Apoptosis ◽  
Bladder Cancer Cells ◽  
Anti Inflammatory

1216: Oral Treatment with a Vitamin D3 Analogue Shows Anti Inflammatory Effects and Reduces Bladder Overactivity in Rodent Models of Chronic Cystitis

2005 ◽  
Vol 173 (4S) ◽  
pp. 330-330
Author(s):  
Peter Zvara ◽  
Fabio Benigni ◽  
Enrico Baroni ◽  
Marija Zecevic ◽  
Antonia Monno ◽  
...  
Keyword(s):  
Vitamin D3 ◽  
Oral Treatment ◽  
Rodent Models ◽  
Chronic Cystitis ◽  
Anti Inflammatory
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