Grape anthocyanin oligomerization: A putative mechanism for red color stabilization?

2014 ◽  
Vol 105 ◽  
pp. 178-185 ◽  
Author(s):  
Joana Oliveira ◽  
Natércia F. Brás ◽  
Mara Alhinho da Silva ◽  
Nuno Mateus ◽  
A. Jorge Parola ◽  
...  
Keyword(s):  

In this study, once-daily porosity osmotic pump tablets (POPTs) of Glimepiride were prepared using HPMC K100M (61%), osmotic agent (30% NaCl) coated using two different coating techniques spraying and dipping methods. The coating solution composed of ethyl cellulose (7.5%) w\w in ethanol (90%), castor oil (2%) as water-insoluble plasticizer and Gingo red color (0.5% w\w). In both techniques, the coating level was adjusted to give a 10% increase in the weight of the tablets. The effect of the coating by dipping technique with an increase in the weight of tablet (10 %, 20% & 50%) was also investigated to see the effect coating level on the percentage of drug release from POPTs. The results of the in vitro release of Glimepiride from tablets coated by the spraying method showed longer release time (24 hrs) than those coated with dipping method. On the other hand, increasing the coating level by dipping method retarded the release of the drug from tablets. However, the same retardation effect on release as shown with the spraying technique was only obtained by increasing the coating level with a 50% increase in the weight of the tablet. Thus, coating by spraying is more efficient to prepare POPTs to give a continuous release of Glimepiride from once daily table with the lowest increase in the total weight of the tablet.


Alloy Digest ◽  
2002 ◽  
Vol 51 (12) ◽  

Abstract Wieland-M15 is copper-zinc alloy with good electrical conductivity and a red color useful in decorative applications. The alloy has also been called red brass, 85%, and CA 230. This datasheet provides information on composition, physical properties, hardness, elasticity, tensile properties, and bend strength. It also includes information on corrosion resistance as well as forming, heat treating, and joining. Filing Code: CU-694. Producer or source: Wieland Metals Inc., Wieland-Werke AG.


HortScience ◽  
1998 ◽  
Vol 33 (3) ◽  
pp. 548a-548 ◽  
Author(s):  
D.M. Glenn ◽  
G. Puterka ◽  
T. Baugher ◽  
T. Unruh ◽  
S. Drake

Hydrophobic particle film technology (HPF) is a developing pest control system for tree fruit production systems. Studies were established in Chile, and Washington, Pennsylvania, and West Virginia in the United States, to evaluate the effect of HPF technology on tree fruit yield and quality. Studies in Chile, Washington, and West Virginia demonstrated increased photosynthetic rate at the leaf level. Yield was increased in peaches (Chile) and apples (West Virginia), and fruit size was increased in apples (Washington and Pennsylvania). Increased red color in apple was demonstrated at all sites with reduced russetting and `Stayman' cracking in Pennsylvania. HPF technology appears to be an effective tool in reducing water and heat stress in tree fruit resulting in increased fruit quality.


2019 ◽  
Vol 35 (5) ◽  
pp. 36-41
Author(s):  
V.A. Zenin ◽  
E.G. Sadykhov ◽  
A.N. Fedorov

A strategy of sequential dimerization of monomers of antimicrobial peptides (AMPs) into one polypeptide chain has been implemented on the example of a beta-structural AMP polyphemusin I which is one of the most effective candidate for use as an antibiotic. The possible polyphemusin I monomer and dimer structures in lipid membrane were studied in this work via molecular modeling. To this end, these molecules were chemically synthesized so that the dimer represented two monomers connected in series into one polypeptide chain with a flexible linker. The antimicrobial effects of monomer and dimer were then tested on various bacterial cultures, and their similarity was shown. Therefore, we can conclude that the pore formation is not a putative mechanism of the polyphemusin I action. antimicrobial peptides, peptide dimerization, mechanism of antimicrobial action, polyphemusin The work was supported by the Ministry of Science and Higher Education of the Russian Federation (Project Unique Identifier RFMEFI57517X0151).


1983 ◽  
Vol 29 (8) ◽  
pp. 1513-1517 ◽  
Author(s):  
M W McGowan ◽  
J D Artiss ◽  
B Zak

Abstract A procedure for the enzymatic determination of lecithin and sphingomyelin in aqueous solution is described. The phospholipids are first dissolved in chloroform:methanol (2:1 by vol), the solvent is evaporated, and the residue is redissolved in an aqueous zwitterionic detergent solution. The enzymatic reaction sequences of both assays involve hydrolysis of the phospholipids to produce choline, which is then oxidized to betaine, thus generating hydrogen peroxide. The hydrogen peroxide is subsequently utilized in the enzymatic coupling of 4-aminoantipyrine and sodium 2-hydroxy-3,5-dichlorobenzenesulfonate, an intensely red color being formed. The presence of a non-reacting phospholipid enhances the hydrolysis of the reacting phospholipid. Thus we added lecithin to the sphingomyelin standards and sphingomyelin to the lecithin standards. This precise procedure may be applicable to determination of lecithin and sphingomyelin in amniotic fluid.


Polymer ◽  
2019 ◽  
Vol 179 ◽  
pp. 121612 ◽  
Author(s):  
Tuan-Qing Liu ◽  
Feng Zheng ◽  
Tong-Mei Ding ◽  
Shu-Yu Zhang ◽  
Qinghua Lu

2003 ◽  
Vol 14 (04) ◽  
pp. 202-212 ◽  
Author(s):  
Michael J. Cevette ◽  
Jürgen Vormann ◽  
Kay Franz

The last several decades have revealed clinical and experimental data regarding the importance of magnesium (Mg) in hearing. Increased susceptibility to noise damage, ototoxicity, and auditory hyperexcitibility are linked to states of Mg deficiency. Evidence for these processes has come slowly and direct effects have remained elusive because plasma Mg levels do not always correlate with its deficiency. Despite the major progress in the understanding of cochlear mechanical and auditory nerve function, the neurochemical and pharmacologic role of Mg is not clear. The putative mechanism suggests that Mg deficiency may contribute to a metabolic cellular cascade of events. Mg deficiency leads to an increased permeability of the calcium channel in the hair cells with a consequent over influx of calcium, an increased release of glutamate via exocytosis, and over stimulation of NMDA receptors on the auditory nerve. This paper provides a current overview of relevant Mg metabolism and deficiency and its influence on hearing.


Coatings ◽  
2021 ◽  
Vol 11 (6) ◽  
pp. 660
Author(s):  
Qingqing Liu ◽  
Di Gao ◽  
Wei Xu

According to the old surface coating process of European and American furniture, the surface of modified poplar is first differentiated pre-treatment, and then the bottom color modification and material color modification are respectively applied to the modified poplar after the surface differentiation treatment. The visual physical quantity and physical and chemical properties were measured and compared with mahogany, which is commonly used in old furniture in Europe and America to explore the effect of colorants and coloring steps, as well as different surface pretreatments on the coloring effect. Finally, it is concluded that continuous coloring operations can narrow the difference in brightness and red color value in the coloring layer of modified poplar and mahogany. Continuous coloring operations increase the difference between the yellow-green color values of modified poplar and mahogany. Therefore, the coloring difference between modified poplar and mahogany was affected by the colorant and coloring steps. Through color accumulation, the gap between the two in the target color coloring effect can be reduced, thereby reducing the difference between the coloring effect of modified poplar and mahogany.


2017 ◽  
Vol 144 (2) ◽  
pp. 172-185 ◽  
Author(s):  
Rajkumar Vutukuri ◽  
Robert Brunkhorst ◽  
Roxane-Isabelle Kestner ◽  
Lena Hansen ◽  
Nerea Ferreiros Bouzas ◽  
...  

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