Stimulus (polyphenol, IFN-γ, LPS)-dependent nitric oxide production and antileishmanial effects in RAW 264.7 macrophages

2008 ◽  
Vol 69 (18) ◽  
pp. 3103-3110 ◽  
Author(s):  
Herbert Kolodziej ◽  
Oliver A. Radtke ◽  
Albrecht F. Kiderlen
Keyword(s):  
Nitric Oxide ◽  
Raw 264.7 ◽  
Nitric Oxide Production ◽  
Raw 264.7 Macrophages ◽  
Oxide Production ◽  
Ifn Γ

scholarly journals Effect of Compounds Isolated from Natural Products on IFN-γ/LPS–Induced Nitric Oxide Production in RAW 264.7 Macrophages

2006 ◽  
Vol 44 (1) ◽  
pp. 50-59 ◽  
Author(s):  
A. Syahida ◽  
D.A. Israf ◽  
N.H. Lajis ◽  
S. Khozirah ◽  
M. Habsah ◽  
...  
Keyword(s):  
Nitric Oxide ◽  
Natural Products ◽  
Raw 264.7 ◽  
Nitric Oxide Production ◽  
Raw 264.7 Macrophages ◽  
Oxide Production ◽  
Ifn Γ

Inhibitory Effect of Trimidox on Lipopolysaccharide-Induced Nitric Oxide Production in RAW 264.7 Macrophages

2007 ◽  
Vol 104 (3) ◽  
pp. 278-281 ◽  
Author(s):  
Syu-ichi Kanno ◽  
Mai Kakuta ◽  
Yasue Kitajima ◽  
Yuu Osanai ◽  
Kaori Kurauchi ◽  
...  
Keyword(s):  
Nitric Oxide ◽  
Inhibitory Effect ◽  
Raw 264.7 ◽  
Nitric Oxide Production ◽  
Raw 264.7 Macrophages ◽  
Oxide Production

scholarly journals Pomegranate juice down‐regulates nitric oxide production in RAW 264.7 macrophages challenged with lipopolysaccharides

2006 ◽  
Vol 20 (4) ◽  
Author(s):  
Jennifer A Powell ◽  
Sachin Mahajan ◽  
Shirin Hooshmand ◽  
Brenda J Smith ◽  
Bahram H Arjmandi ◽  
...  
Keyword(s):  
Nitric Oxide ◽  
Pomegranate Juice ◽  
Raw 264.7 ◽  
Nitric Oxide Production ◽  
Raw 264.7 Macrophages ◽  
Oxide Production

Inhibitory effects of cranberry polyphenol and volatile extracts on nitric oxide production in LPS activated RAW 264.7 macrophages

2019 ◽  
Vol 10 (11) ◽  
pp. 7091-7102 ◽  
Author(s):  
Katie Moore ◽  
Luke Howard ◽  
Cindi Brownmiller ◽  
Inah Gu ◽  
Sun-Ok Lee ◽  
...  
Keyword(s):  
Nitric Oxide ◽  
Raw 264.7 ◽  
Nitric Oxide Production ◽  
Inhibitory Effects ◽  
Raw 264.7 Macrophages ◽  
Oxide Production ◽  
Health Promoting

Cranberry volatiles have received little attention for health-promoting properties.

Ultra-wideband pulses increase nitric oxide production by RAW 264.7 macrophages incubated in nitrate

2001 ◽  
Vol 23 (1) ◽  
pp. 83-87 ◽  
Author(s):  
Ronald L. Seaman ◽  
Jill E. Parker ◽  
Johnathan L. Kiel ◽  
Satnam P. Mathur ◽  
Teri R. Grubbs ◽  
...  
Keyword(s):  
Nitric Oxide ◽  
Ultra Wideband ◽  
Raw 264.7 ◽  
Nitric Oxide Production ◽  
Raw 264.7 Macrophages ◽  
Oxide Production

scholarly journals Inhibition of nitric oxide production in lipopolysaccharide-activated RAW 264.7 macrophages by Jeju plant extracts

2009 ◽  
Vol 2 (4) ◽  
pp. 245-249 ◽  
Author(s):  
Eun-Jin Yang ◽  
Eun-Young Yim ◽  
Gwanpil Song ◽  
Gi-Ok Kim ◽  
Chang-Gu Hyun
Keyword(s):  
Nitric Oxide ◽  
Plant Extracts ◽  
Inhibitory Activity ◽  
Inflammatory Diseases ◽  
No Production ◽  
Raw 264.7 ◽  
Nitric Oxide Production ◽  
Raw 264.7 Macrophages ◽  
Oxide Production ◽  
Potent Inhibition

Inhibition of nitric oxide production in lipopolysaccharide-activated RAW 264.7 macrophages by Jeju plant extractsNitric oxide (NO) produced in large amounts by inducible nitric oxide synthase (iNOS) is known to be responsible for the vasodilation and hypotension observed during septic shock and inflammation. Thus, inhibitors of iNOS may be useful candidates for the treatment of inflammatory diseases accompanied by the overproduction of NO. In this study, we prepared alcoholic extracts of Jeju plants and screened them for their inhibitory activity against NO production in lipopolysaccharide (LPS)-activated macrophages. Among the 260 kinds of plant extract tested, 122 extracts showed potent inhibitory activity towards NO production by more than 25% at a concentration of 100 μg/mL. Plants such asMalus sieboldii, Vaccinium oldhamii, Corylus hallaisanensis, Carpinus laxiflora, Styrax obassia, andSecurinega suffruticosashowed the most potent inhibition (above 70%) at a concentration of 100 μg/mL. The cytotoxic effects of the plant extracts were determined by colorimetric MTT assays and most plant extracts exhibited only moderate cytotoxicity at 100 μg/mL. Therefore, these plants should be considered promising candidates for the further purification of bioactive compounds and would be useful for the treatment of inflammatory diseases accompanying overproduction of NO.

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