Working across service boundaries: facilitating timely access to respiratory management for people with motor neuron disease (MND)

Physiotherapy ◽  
2017 ◽  
Vol 103 ◽  
pp. e72-e73
Author(s):  
C. Canova ◽  
M. Krzyszkowska ◽  
R. Preema ◽  
S.K. Mansell
Keyword(s):  
Motor Neuron ◽  
Motor Neuron Disease ◽  
Respiratory Management ◽  
Timely Access

scholarly journals Multidisciplinary Interventions in Motor Neuron Disease

2014 ◽  
Vol 2014 ◽  
pp. 1-10 ◽  
Author(s):  
U. E. Williams ◽  
E. E. Philip-Ephraim ◽  
S. K. Oparah
Keyword(s):  
Motor Neuron ◽  
Motor Neuron Disease ◽  
Motor Neurons ◽  
Neuronal Cell ◽  
Cell Loss ◽  
Cellular Processes ◽  
Team Care ◽  
Respiratory Management ◽  
Care Approach ◽  
Management Of Dysphagia

Motor neuron disease is a neurodegenerative disease characterized by loss of upper motor neuron in the motor cortex and lower motor neurons in the brain stem and spinal cord. Death occurs 2–4 years after the onset of the disease. A complex interplay of cellular processes such as mitochondrial dysfunction, oxidative stress, excitotoxicity, and impaired axonal transport are proposed pathogenetic processes underlying neuronal cell loss. Currently evidence exists for the use of riluzole as a disease modifying drug; multidisciplinary team care approach to patient management; noninvasive ventilation for respiratory management; botulinum toxin B for sialorrhoea treatment; palliative care throughout the course of the disease; and Modafinil use for fatigue treatment. Further research is needed in management of dysphagia, bronchial secretion, pseudobulbar affect, spasticity, cramps, insomnia, cognitive impairment, and communication in motor neuron disease.

Thr124Met myelin protein zero mutation mimicking motor neuron disease

2021 ◽  
pp. 1-6
Author(s):  
Giulia Bisogni ◽  
Angela Romano ◽  
Amelia Conte ◽  
Giorgio Tasca ◽  
Daniela Bernardo ◽  
...  
Keyword(s):  
Motor Neuron ◽  
Motor Neuron Disease ◽  
Myelin Protein ◽  
Myelin Protein Zero ◽  
Protein Zero

Late onset Sandhoff disease presenting with lower motor neuron disease and stuttering

2021 ◽  
Author(s):  
Jorge Alonso-Pérez ◽  
Ana Casasús ◽  
Álvaro Gimenez-Muñoz ◽  
Jennifer Duff ◽  
Ricard Rojas-Garcia ◽  
...  
Keyword(s):  
Motor Neuron ◽  
Motor Neuron Disease ◽  
Late Onset ◽  
Sandhoff Disease ◽  
Lower Motor Neuron ◽  
Lower Motor Neuron Disease

scholarly journals Longitudinal clinical and neuroanatomical correlates of memory impairment in motor neuron disease

2021 ◽  
Vol 29 ◽  
pp. 102545
Author(s):  
Judith Machts ◽  
Marius Keute ◽  
Joern Kaufmann ◽  
Stefanie Schreiber ◽  
Elisabeth Kasper ◽  
...  
Keyword(s):  
Motor Neuron ◽  
Motor Neuron Disease ◽  
Memory Impairment
Sign in / Sign up

Export Citation Format

Share Document