Sexual experience with a known male modulates c-Fos expression in response to mating and male pheromone exposure in female mice

2020 ◽  
Vol 222 ◽  
pp. 112906 ◽  
Author(s):  
P. Marco-Manclus ◽  
R.G. Paredes ◽  
W. Portillo
Keyword(s):  
Sexual Experience ◽  
Male Pheromone ◽  
Female Mice ◽  
Fos Expression

Deficient hippocampal c-fos expression results in reduced anxiety and altered response to chronic stress in female mice

2006 ◽  
Vol 403 (1-2) ◽  
pp. 125-130 ◽  
Author(s):  
Jill M. Slane McQuade ◽  
Kellie L.K. Tamashiro ◽  
Gwendolyn E. Wood ◽  
James P. Herman ◽  
Bruce S. McEwen ◽  
...  
Keyword(s):  
Chronic Stress ◽  
Female Mice ◽  
Altered Response ◽  
Fos Expression

scholarly journals Male-pheromone effect on the efficiency of pregnancy in female mice

Reproduction ◽  
1980 ◽  
Vol 58 (2) ◽  
pp. 363-367 ◽  
Author(s):  
A. Marchlewska-Koj ◽  
B. Jemiolo ◽  
J. Wozniacka ◽  
K. Kozlowski
Keyword(s):  
Male Pheromone ◽  
Female Mice

Comparison of c-Fos expression in brain regions involved in maternal behavior of virgin and lactating female mice

2015 ◽  
Vol 590 ◽  
pp. 166-171 ◽  
Author(s):  
Nao Matsushita ◽  
Yoshikage Muroi ◽  
Ken-ichi Kinoshita ◽  
Toshiaki Ishii
Keyword(s):  
Maternal Behavior ◽  
Brain Regions ◽  
Female Mice ◽  
Fos Expression

MK-801 and male odours induce c-fos expression in the AOB of juvenile female mice

Neuroreport ◽  
1998 ◽  
Vol 9 (17) ◽  
pp. 3919-3924 ◽  
Author(s):  
R Ashley McLellan ◽  
Michael Wilkinson ◽  
Richard E. Brown
Keyword(s):  
Mk 801 ◽  
Juvenile Female ◽  
Female Mice ◽  
Fos Expression

Effect of Familiarity With the Mother and Kinship On Infanticidal and Alloparental Behaviour in Virgin House Mice

Behaviour ◽  
1993 ◽  
Vol 124 (3-4) ◽  
pp. 313-326 ◽  
Author(s):  
Francesca R. D'Amato
Keyword(s):  
Kin Recognition ◽  
Sexual Experience ◽  
Alloparental Care ◽  
House Mice ◽  
Reproductive Condition ◽  
Male And Female ◽  
Female Mice ◽  
Experienced Male ◽  
Virgin Male ◽  
Female Behaviour

AbstractExperienced male and female house mice encountering a newborn pup can display indifference, parental or infanticidal behaviour. Characteristics of the pup such as sex and strain do not seem to influence the likelihood of infanticide, in contrast to attributes of the adult subjects (age, sex, strain, sexual experience, previous cohabitation with the mother, reproductive condition). This study investigated the effect of kinship and/or familiarity with the mother on male and female behaviour towards pups. The subjects were 100-day-old Swiss-Webster virgin male and female mice. After 24 hours of isolation, a 24-36 hrs old pup was introduced into their home-cage and their behaviour was recorded for 15 min. Male and female mice killed related as well as unrelated pups. Females killed fewer offspring of females with whom they had cohabited until 3 weeks before the study, in comparison with the offspring of completely unfamiliar females. When females were exposed to the offspring of females of comparable familiarity but different relatedness, they devoted more parental behaviour towards more related pups. This suggests that, even if familiarity plays a major role in determining females' behaviour, kin recognition occurs and is responsible for differences in alloparental care distribution. The behavioural strategies adopted by male and female mice are interpreted on the basis of differences in activity range of the sexes within a deme (breeding group).

scholarly journals Absence of Female-Typical Pheromone-Induced Hypothalamic Neural Responses and Kisspeptin Neuronal Activity in α-Fetoprotein Knockout Female Mice

Endocrinology ◽  
2015 ◽  
Vol 156 (7) ◽  
pp. 2595-2607 ◽  
Author(s):  
Melanie Taziaux ◽  
Julie Bakker
Keyword(s):  
Protein Product ◽  
Early Gene ◽  
Sexually Dimorphic ◽  
Neural Responses ◽  
Female Mice ◽  
Gnrh Neurons ◽  
Opposite Sex ◽  
Neuroendocrine Responses ◽  
Fos Expression ◽  
Lh Secretion

Pheromones induce sexually dimorphic neuroendocrine responses, such as LH secretion. However, the neuronal network by which pheromones are converted into signals that will initiate and modulate endocrine changes remains unclear. We asked whether 2 sexually dimorphic populations in the anteroventral periventricular and periventricular nuclei that express kisspeptin and tyrosine hydroxylase (TH) are potential candidates that will transduce the olfactory signal to the neuroendocrine system. Furthermore, we assessed whether this transduction is sensitive to perinatal actions of estradiol by using female mice deficient in α-fetoprotein (AfpKO), which lack the protective actions of Afp against maternal estradiol. Wild-type (WT) and AfpKO male and female mice were exposed to same- versus opposite-sex odors and the expression of Fos (the protein product of the immediate early gene c-Fos) was analyzed along the olfactory projection pathways as well as whether kisspeptin, TH, and GnRH neurons are responsive to opposite-sex odors. Male odors induced a female-typical Fos expression in target forebrain sites of olfactory inputs involved in reproduction in WT, but not in AfpKO females, whereas female odors induced a male-typical Fos expression in males of both genotypes. In WT females, opposite-sex odors induced Fos in kisspeptin and TH neurons, whereas in AfpKO females and WT males, only a lower, but still significant, Fos expression was observed in TH but not in kisspeptin neurons. Finally, opposite-sex odors did not induce any significant Fos expression in GnRH neurons of both sexes or genotypes. Our results strongly suggest a role for fetal estrogen in the sexual differentiation of neural responses to sex-related olfactory cues.

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