scholarly journals Learning and behavior in hatchling Trachemys scripta exposed to bisphenol-a during embryonic development

2019 ◽  
Vol 209 ◽  
pp. 112614
Author(s):  
Justin Dillard ◽  
Amanda Wilson Carter ◽  
Geoff D. Ower ◽  
Ryan T. Paitz ◽  
Rachel M. Bowden
Keyword(s):  
Embryonic Development ◽  
Bisphenol A ◽  
Trachemys Scripta ◽  
And Behavior

scholarly journals The role of Bisphenol A in shaping the brain, epigenome and behavior

2011 ◽  
Vol 59 (3) ◽  
pp. 296-305 ◽  
Author(s):  
Jennifer T. Wolstenholme ◽  
Emilie F. Rissman ◽  
Jessica J. Connelly
Keyword(s):  
Bisphenol A ◽  
And Behavior ◽  
The Brain

Associations of Prenatal Urinary Bisphenol A Concentrations with Child Cognition and Behavior

2016 ◽  
Vol 2016 (1) ◽  
Author(s):  
Joseph Braun* ◽  
Bruce Lanphear ◽  
Tye Arbuckle ◽  
William Fraser ◽  
Youssef Oulhote ◽  
...  
Keyword(s):  
Bisphenol A ◽  
Child Cognition ◽  
And Behavior

Bisphenol A (BPA) and atrazine inhibit the embryonic development ofCiona intestinalis(Ascidiacea, Urochordata)

Caryologia ◽  
2013 ◽  
Vol 66 (2) ◽  
pp. 97-102 ◽  
Author(s):  
Maria Vittoria Cangialosi ◽  
Valentina Mansueto ◽  
Ali S. Faqi
Keyword(s):  
Embryonic Development ◽  
Bisphenol A

Influence of bisphenol A on genome-wide DNA methylation level in different sections of a mouse body on the 12th day of embryonic development

2018 ◽  
Vol 53 (3) ◽  
pp. 96
Author(s):  
Irina O. Suchkova ◽  
Ekaterina M. Noniashvili ◽  
Natal`ya I. Dergacheva ◽  
Van Truong Tran ◽  
Lyudmila K. Sasina ◽  
...  
Keyword(s):  
Dna Methylation ◽  
Embryonic Development ◽  
Bisphenol A ◽  
Methylation Level ◽  
Genome Wide

scholarly journals Biological activity of oestradiol sulphate in an oviparous amniote: implications for maternal steroid effects

2010 ◽  
Vol 278 (1714) ◽  
pp. 2005-2010 ◽  
Author(s):  
Ryan T. Paitz ◽  
Rachel M. Bowden
Keyword(s):  
Biological Activity ◽  
Embryonic Development ◽  
Phenotypic Variation ◽  
Female Offspring ◽  
Dynamic Interaction ◽  
Trachemys Scripta ◽  
In Ovo ◽  
Steroid Production ◽  
Slider Turtle ◽  
The Many

Understanding the many factors that underlie phenotypic variation is of profound importance to evolutionary biologists. The embryonic endocrine environment is one such factor that has received much attention. In placental amniotes, the dynamic interaction of maternal and embryonic steroid production and metabolism is critical to regulating the endocrine environment. Less is known about how embryos of oviparous amniotes regulate their endocrine environment because most studies have focused on relating initial steroid levels in the yolk at oviposition to offspring phenotype. We tested the hypothesis that embryos of oviparous amniotes regulate their endocrine environment by conjugating maternal steroids and subsequently using the metabolites as precursors for steroid production later in development. Using the red-eared slider turtle ( Trachemys scripta ), we first characterized the conjugation of exogenous oestradiol to either oestradiol glucuronide or oestradiol sulphate (E 2 -S) in ovo during the first 15 days of development. Results show that oestradiol is primarily conjugated to E 2 -S. We then examined whether E 2 -S influenced sex determination and report that E 2 -S increases the production of female offspring. These data demonstrate that oviparous amniotes can both sulphonate steroids and respond to sulphonated steroids during embryonic development in a manner similar to placental amniotes.

A Physiologically Based Approach To the Study of Bisphenol a and Other Estrogenic Chemicals On the Size of Reproductive Organs, Daily Sperm Production, and Behavior

1998 ◽  
Vol 14 (1-2) ◽  
pp. 239-260 ◽  
Author(s):  
Frederick S. Vom Saal ◽  
Paul S. Cooke ◽  
David L. Buchanan ◽  
Paola Palanza ◽  
Kristina A. Thayer ◽  
...  
Keyword(s):  
Bisphenol A ◽  
Estrogenic Activity ◽  
Reproductive Organs ◽  
Average Concentration ◽  
Sperm Production ◽  
Brain And Behavior ◽  
Estrogenic Chemicals ◽  
Physiologically Based Approach ◽  
And Behavior ◽  
Daily Sperm Production

Two chemicals previously shown to have estrogenic activity, bisphenol A and octylphenol, were examined for their effects on accessory reproductive organs and daily sperm production in male offspring of mice fed these chemicals during pregnancy. These chemicals are used in the manufacture of plastics and other products, and have been detected in food and water consumed by animals and people. From gestation day 11-17 female mice were fed an average concentration (dissolved in oil) of bisphenol A or octylphenol of 2 ng/g body weight (2 ppb) and 20 ng/g (20 ppb). The 2 ppb dose of bisphenol A is lower than the amount reported to be swallowed during the first hour after application of a plastic dental sealant (up to 931 μg; 13.3 ppb in a 70 kg adult). We found that the 2 ng/g dose of bisphenol A permanently increased the size of the preputial glands, but reduced the size of the epididymides; these organs develop from different embryonic tissues. At 20 ng/g, bisphenol A significantly decreased efficiency of sperm production (daily sperm production per g testis) by 20% relative to control males. The only significant effect of octylphenol was a reduction in daily sperm production and efficiency of sperm production at the 2 ng/g dose. A new approach to studying physiologically relevant doses of environmental endocrine disruptors is discussed, particularly with regard to the development of the reproductive organs, the brain, and behavior.

scholarly journals Evaluation of the Toxicity of Bisphenol A in Reproduction and Its Effect on Fertility and Embryonic Development in the Zebrafish (Danio rerio)

2022 ◽  
Vol 19 (2) ◽  
pp. 962
Author(s):  
Lilian de Paula Gonçalves Reis ◽  
Antonio Jesús Lora-Benítez ◽  
Ana Mª Molina-López ◽  
Rafael Mora-Medina ◽  
Nahúm Ayala-Soldado ◽  
...  
Keyword(s):  
Embryonic Development ◽  
Bisphenol A ◽  
Danio Rerio ◽  
Chemical Substance ◽  
Toxic Effects ◽  
Control Group ◽  
Histopathological Study ◽  
Parental Exposure ◽  
Electron Microscopes ◽  
Histopathological Studies

Bisphenol A (BPA) is a chemical substance commonly used in the manufacture of plastic products. Its inhalation or ingestion from particles in suspension, water, and/or polluted foods can trigger toxic effects related to endocrine disruption, resulting in hormonal, reproduction, and immunological alterations in humans and animals. The zebrafish (Danio rerio) is an ideal experimental model frequently used in toxicity studies. In order to assess the toxic effects of BPA on reproduction and embryonic development in one generation after parental exposure to it, a total of 80 zebrafish, males and females, divided into four groups in duplicate (n = 20) were exposed to BPA concentrations of 500, 50, and 5 µg L−1, along with a control group. The fish were kept in reproduction aquariums for 21 days. The embryos obtained in the crosses were incubated in a BPA-free medium and observed for signs of embryotoxicity. A histopathological study (under optical and electron microscopes) was performed of adult fish gonads. The embryos of reproducers exposed to BPA were those most frequently presenting signs of embryotoxicity, such as mortality and cardiac and musculoskeletal malformations. In the histopathological studies of adult individuals, alterations were found in ovocyte maturation and in spermatazoid formation in the groups exposed to the chemical. Those alterations were directly related to BPA action, affecting fertility in both sexes, as well as the viability of their offspring, proportionally to the BPA levels to which they were exposed, so that our results provide more information by associating toxic effects on the offspring and on the next generation.

Acute toxicity of nonylphenols and bisphenol A to the embryonic development of the abalone Haliotis diversicolor supertexta

Ecotoxicology ◽  
2011 ◽  
Vol 20 (6) ◽  
pp. 1233-1245 ◽  
Author(s):  
Ying Liu ◽  
Nora F. Y. Tam ◽  
Yuntao Guan ◽  
Makoto Yasojima ◽  
Jin Zhou ◽  
...  
Keyword(s):  
Acute Toxicity ◽  
Embryonic Development ◽  
Bisphenol A ◽  
Haliotis Diversicolor ◽  
Haliotis Diversicolor Supertexta ◽  
Diversicolor Supertexta
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