Institutionalization and indiscriminate social behavior: Differential-susceptibility versus diathesis-stress models for the 5-HTTLPR and BDNF genotypes

Moderation of associations between interparental stress and (mal)adaptation by adolescents' personality: Contrasting differential susceptibility and diathesis–stress models

Journal of Personality ◽

10.1111/jopy.12603 ◽

2020 ◽

Author(s):

Willemijn M. Eldik ◽

Amaranta D. Haan ◽

Lidia R. Arends ◽

Peter Prinzie

Keyword(s):

Differential Susceptibility ◽

Stress Models

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Interaction Effects of Life Events and Hair Cortisol on Perceived Stress, Anxiety, and Depressive Symptoms Among Chinese Adolescents: Testing the Differential Susceptibility and Diathesis-Stress Models

Frontiers in Psychology ◽

10.3389/fpsyg.2019.00297 ◽

2019 ◽

Vol 10 ◽

Cited By ~ 1

Author(s):

Youyun Xu ◽

Yapeng Liu ◽

Zheng Chen ◽

Jing Zhang ◽

Huihua Deng ◽

...

Keyword(s):

Depressive Symptoms ◽

Life Events ◽

Perceived Stress ◽

Differential Susceptibility ◽

Interaction Effects ◽

Chinese Adolescents ◽

Hair Cortisol ◽

Stress Models

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Distinguishing differential susceptibility from diathesis–stress: Recommendations for evaluating interaction effects

Development and Psychopathology ◽

10.1017/s0954579412000065 ◽

2012 ◽

Vol 24 (2) ◽

pp. 389-409 ◽

Cited By ~ 261

Author(s):

Glenn I. Roisman ◽

Daniel A. Newman ◽

R. Chris Fraley ◽

John D. Haltigan ◽

Ashley M. Groh ◽

...

Keyword(s):

Child Care ◽

Youth Development ◽

Differential Susceptibility ◽

Academic Skills ◽

Interaction Effects ◽

Early Child ◽

Early Child Care ◽

Susceptibility Effects ◽

Maternal Caregiving ◽

Stress Models

AbstractThis report describes the state of the art in distinguishing data generated by differential susceptibility from diathesis–stress models. We discuss several limitations of existing practices for probing interaction effects and offer solutions that are designed to better differentiate differential susceptibility from diathesis–stress models and quantify their corresponding implications. In addition, we demonstrate the utility of these methods by revisiting published evidence suggesting that temperamental difficulty serves as a marker of enhanced susceptibility to early maternal caregiving across a range of outcome domains in the NICHD Study of Early Child Care and Youth Development. We find that, with the exception of mother reports of psychopathology, there is consistent evidence in the Study of Early Child Care and Youth Development that the predictive significance of early sensitivity is moderated by difficult temperament over time. However, differential susceptibility effects emerged primarily for teacher reports of academic skills, social competence, and symptomatology. In contrast, effects more consistent with the diathesis–stress model were obtained for mother reports of social skills and objective tests of academic skills. We conclude by discussing the value of the application of this work to the next wave of Gene × Environment studies focused on early caregiving experiences.

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Differential susceptibility to effects of maternal sensitivity? A study of candidate plasticity genes

Development and Psychopathology ◽

10.1017/s0954579414000844 ◽

2014 ◽

Vol 27 (3) ◽

pp. 725-746 ◽

Cited By ~ 27

Author(s):

Jay Belsky ◽

Daniel A. Newman ◽

Keith F. Widaman ◽

Phil Rodkin ◽

Michael Pluess ◽

...

Keyword(s):

Candidate Genes ◽

Maternal Sensitivity ◽

Differential Susceptibility ◽

Environment Interaction ◽

Social Emotional ◽

Gene Environment Interaction ◽

Gene Environment ◽

Current Sample ◽

Stress Models ◽

Main Effects

AbstractHere we tested whether there was genetic moderation of effects of early maternal sensitivity on social–emotional and cognitive–linguistic development from early childhood onward and whether any detected Gene × Environment interaction effects proved consistent with differential-susceptibility or diathesis–stress models of Person × Environment interaction (N= 695). Two new approaches for evaluating models were employed with 12 candidate genes. Whereas maternal sensitivity proved to be a consistent predictor of child functioning across the primary-school years, candidate genes did not show many main effects, nor did they tend to interact with maternal sensitivity/insensitivity. These findings suggest that the developmental benefits of early sensitive mothering and the costs of insensitive mothering look more similar than different across genetically different children in the current sample. Although acknowledgement of this result is important, it is equally important that the generally null Gene × Environment results reported here not be overgeneralized to other samples, other predictors, other outcomes, and other candidate genes.

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