Green tea catechins, caffeine and body-weight regulation

2010 ◽  
Vol 100 (1) ◽  
pp. 42-46 ◽  
Author(s):  
M.S. Westerterp-Plantenga
Keyword(s):  
Body Weight ◽  
Green Tea ◽  
Weight Regulation ◽  
Body Weight Regulation ◽  
Tea Catechins ◽  
Green Tea Catechins

scholarly journals Health effects of green tea catechins in overweight and obese men: a randomised controlled cross-over trial

2011 ◽  
Vol 106 (12) ◽  
pp. 1880-1889 ◽  
Author(s):  
A. L. Brown ◽  
J. Lane ◽  
C. Holyoak ◽  
B. Nicol ◽  
A. E. Mayes ◽  
...  
Keyword(s):  
Blood Pressure ◽  
Body Weight ◽  
Health Effects ◽  
Green Tea ◽  
Metabolic Flux ◽  
Epigallocatechin Gallate ◽  
Metabolic Function ◽  
Tea Catechins ◽  
Green Tea Catechins ◽  
Modifying Effect

Regular consumption of green tea may be cardioprotective. In the present study we investigated the health effects of dietary supplementation with green tea catechins and the potential modifying effect of the catechol-O-methyltransferase (COMT) Val/Met genotype. Subjects (sedentary males, aged 40–69 years, with BMI ≥  28 and ≤  38 kg/m2) were randomly assigned to consume decaffeinated green tea extract (DGT; 530 mg containing about 400 mg total catechins/capsule, twice daily) and placebo in a complete cross-over design. Ambulatory blood pressure and biomarkers of metabolic function (cholesterol, TAG, glucose and insulin) were measured at weeks 0 and 6. Although a marked increase in the concentration of plasma epigallocatechin gallate (EGCG), urinary epigallocatechin (EGC) and urinary 4′-O-methyl EGC was found after DGT treatment, no effect on blood pressure or biomarkers of metabolic function was observed. However, a period × treatment interaction (P < 0·05) was detected for body-weight change. Despite a similar increase in estimated energy intake during intervention period 1, body weight decreased by 0·64 (sd 2·2) kg and increased by 0·53 (sd 1·9) kg in the DGT and placebo groups, respectively (P = 0·025), suggesting a protective effect of green tea catechins on weight gain. Additionally, the COMT Val/Met genotype influenced urinary accumulation of EGC and 4′-O-methyl EGC (P < 0·01). Mean concentrations were lower in individuals homozygous for the high-activity G-allele, possibly reflecting increased metabolic flux and a more rapid conversion to downstream metabolic species, compared with individuals carrying at least one copy of the low-activity A-allele. Additional studies are needed to confirm these findings and further explore the modifying effect of genotype.

Nutraceuticals for body-weight management: The role of green tea catechins

2016 ◽  
Vol 162 ◽  
pp. 83-87 ◽  
Author(s):  
Pilou L.H.R. Janssens ◽  
Rick Hursel ◽  
Margriet S. Westerterp-Plantenga
Keyword(s):  
Body Weight ◽  
Weight Management ◽  
Green Tea ◽  
Tea Catechins ◽  
Green Tea Catechins

Green tea catechins attenuate high-fat diet effects related to obesity and diabetes without effect hypothalamic expression of TLR4 pathway or serotoninergic 1B and 2C receptors

2013 ◽  
Author(s):  
Marcos Hiromu Okuda ◽  
de Santana Aline Alves ◽  
Mayara Franzoi Moreno ◽  
Ana Claudia Hachul ◽  
Nelson Inacio Neto ◽  
...  
Keyword(s):  
Green Tea ◽  
High Fat Diet ◽  
High Fat ◽  
Tea Catechins ◽  
Green Tea Catechins ◽  
Obesity And Diabetes

Non-homeostatic body weight regulation through a brainstem-restricted receptor for GDF15

2018 ◽  
Author(s):  
Hsu JY ◽  
Crawley S ◽  
Chen M ◽  
Ayupova DA ◽  
Lindhout DA ◽  
...  
Keyword(s):  
Body Weight ◽  
Weight Regulation ◽  
Body Weight Regulation

The Protective Effects of Green Tea Catechins in the Management of Neurodegenerative Diseases: A Review

2019 ◽  
Vol 16 (1) ◽  
pp. 57-65 ◽  
Author(s):  
Tahereh Farkhondeh ◽  
Hanieh Shaterzadeh Yazdi ◽  
Saeed Samarghandian
Keyword(s):  
Neurodegenerative Diseases ◽  
Signaling Pathways ◽  
Green Tea ◽  
Molecular Mechanisms ◽  
Main Role ◽  
Related Factor ◽  
Protective Effects ◽  
Tea Catechins ◽  
Green Tea Catechins ◽  
And Control

Background: The therapeutic strategies to manage neurodegenerative diseases remain limited and it is necessary to discover new agents for their prevention and control. Oxidative stress and inflammation play a main role in the pathogenesis of neurodegenerative diseases. The aim of this study is to review the effects of green tea catechins against the Neurodegenerative Diseases. Methods: In this study, we extensively reviewed all articles on the terms of Green tea, catechins, CNS disorders, and different diseases in PubMed, Science Direct, Scopus, and Google Scholar databases between the years 1990 and 2017. Results: The present study found that catechins, the major flavonoids in green tea, are powerful antioxidants and radical scavengers which possess the potential roles in the management of neurodegenerative diseases. Catechins modulate the cellular and molecular mechanisms through the inflammation-related NF-&amp;#954;B and the nuclear factor erythroid 2-related factor 2 (Nrf2) signaling pathways. Conclusion: The findings of the present review shows catechins could be effective against neurodegenerative diseases due to their antioxidation and anti-inflammation effects and the involved biochemical pathways including Nrf2 and NF-kB signaling pathways.<P&gt;

Neuroprotection of green tea catechins on surgical menopause-induced overactive bladder in a rat model

2012 ◽  
Vol 19 (3) ◽  
pp. 346-354 ◽  
Author(s):  
Yung-Shun Juan ◽  
Shu-Mien Chuang ◽  
Cheng-Yu Long ◽  
Chung-Hwan Chen ◽  
Robert M. Levin ◽  
...  
Keyword(s):  
Overactive Bladder ◽  
Green Tea ◽  
Rat Model ◽  
Tea Catechins ◽  
Green Tea Catechins ◽  
Surgical Menopause
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