Dietary trans-fat combined with monosodium glutamate induces dyslipidemia and impairs spatial memory

2010 ◽  
Vol 99 (3) ◽  
pp. 334-342 ◽  
Author(s):  
Kate S. Collison ◽  
Nadine J. Makhoul ◽  
Angela Inglis ◽  
Mohammed Al-Johi ◽  
Marya Zia Zaidi ◽  
...  
Keyword(s):  
Spatial Memory ◽  
Monosodium Glutamate ◽  
Trans Fat

scholarly journals Nutrigenomics of hepatic steatosis in a feline model: effect of monosodium glutamate, fructose, and Trans-fat feeding

2011 ◽  
Vol 7 (2) ◽  
pp. 265-280 ◽  
Author(s):  
Kate S. Collison ◽  
Marya Z. Zaidi ◽  
Soad M. Saleh ◽  
Nadine J. Makhoul ◽  
Angela Inglis ◽  
...  
Keyword(s):  
Hepatic Steatosis ◽  
Monosodium Glutamate ◽  
Trans Fat ◽  
Feline Model ◽  
Fat Feeding

scholarly journals Sex-dimorphism in Cardiac Nutrigenomics: effect of Trans fat and/or Monosodium Glutamate consumption

BMC Genomics ◽  
2011 ◽  
Vol 12 (1) ◽  
Author(s):  
Kate S Collison ◽  
Marya Z Zaidi ◽  
Zakia Maqbool ◽  
Soad M Saleh ◽  
Angela Inglis ◽  
...  
Keyword(s):  
Monosodium Glutamate ◽  
Trans Fat ◽  
Sex Dimorphism

scholarly journals Prediabetic changes in gene expression induced by aspartame and monosodium glutamate in Trans fat-fed C57Bl/6 J mice

2013 ◽  
Vol 10 (1) ◽  
pp. 44 ◽  
Author(s):  
Kate S Collison ◽  
Nadine J Makhoul ◽  
Marya Z Zaidi ◽  
Angela Inglis ◽  
Bernard L Andres ◽  
...  
Keyword(s):  
Gene Expression ◽  
Monosodium Glutamate ◽  
Trans Fat ◽  
In Trans

scholarly journals Subchronic high dose of oral monosodium glutamate causes structural and functional deficits of rat hippocampus

2021 ◽  
Author(s):  
Faizal Muhammad
Keyword(s):  
Body Weight ◽  
Spatial Memory ◽  
Animal Studies ◽  
Monosodium Glutamate ◽  
Pyramidal Cells ◽  
Glutamate Excitotoxicity ◽  
Control Group ◽  
High Dose ◽  
High Concentration ◽  
Hippocampal Pyramidal Cells

The toxicity of monosodium glutamate (MSG) at high concentration has become a controversial issue because of its inconsistent results in human and animal studies. This study aims to investigate the effects of subchronic high doses oral administration of MSG on the spatial memory and the estimated total number of the hippocampal pyramidal cells. This study involved twenty-eight male Wistar rats which were divided into control group and 3 intervention groups (1.0 mg/g body weight, 2.0 mg/g body weight, and 4.0 mg/g body weight) of MSG for 30 days. The estimated number of hippocampal pyramidal cells in the Cornu Ammonis (CA) region including CA1 and CA2-CA3 regions and the data of spatial memory were analyzed using ANOVA test. This study implemented stereological procedures and the precision was evaluated using the formula. The dose of 4 mg/g body weight MSG caused a significant decrease (p = 0.004) in the estimated number of pyramidal cells in CA1, but not in the CA2-CA3 of hippocampus (p = 0.173). The CA1 region were more vulnerable to glutamate excitotoxicity than those in the CA2-CA3 region. The present study has provided novel quantitative data that subchronic high dose of MSG caused deleterious effects on the hippocampal CA1 pyramidal cells and memory consolidation.

Wechsler Memory Scale, Rivermead Behavioral Memory Test, and Everyday Memory Questionnaire in Healthy Adults and Alzheimer Patients

2002 ◽  
Vol 18 (1) ◽  
pp. 63-77 ◽  
Author(s):  
Anastasia Efklides ◽  
Efterpi Yiultsi ◽  
Theopisti Kangellidou ◽  
Fotini Kounti ◽  
Fotini Dina ◽  
...  
Keyword(s):  
Spatial Memory ◽  
Semantic Memory ◽  
Memory Test ◽  
Healthy Adults ◽  
Gender Effects ◽  
Everyday Memory ◽  
Wechsler Memory Scale ◽  
Everyday Memory Questionnaire ◽  
Behavioral Memory ◽  
Memory Questionnaire

Summary: The Wechsler Memory Scale (WMS) is a laboratory-based memory test that has been criticized for its lack of ecological validity and for not testing long-term memory. A more recent memory test, which aims at testing everyday memory, is the Rivermead Behavioral Memory Test (RBMT); it tests prospective memory and other forms of memory not tapped by WMS. However, even this test does not capture all aspects of everyday memory problems often reported by adults. These problems are the object of the Everyday Memory Questionnaire (EMQ). This study aimed at identifying the relationships between these three memory tests. The differential effect of Alzheimer's disease (AD) on the above relationships was also studied. The sample consisted of 233 healthy adults (20 to 75+ years of age) and 39 AD patients (50 to 75 years of age). Confirmatory factor analysis revealed the following latent factors: Verbal Memory, Visual Reconstruction, Orientation, Message (action embedded in spatial context), Visual Recognition, Spatial Memory, New Learning/Association Forming, Prospective/Episodic Memory, and Metamemory. These first-order factors were further explained by two second-order factors: Semantic Memory and Coordination of Semantic and Visuo-Spatial Memory. This basic structure was preserved in the sample of AD patients, although AD patients performed less well on the WMS and the RBMT. Some interesting findings regarding semantic memory, face recognition, and metamemory in AD patients are also reported. Age, education, but no gender effects on memory performance were also detected.

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