scholarly journals Effects of anabolic androgenic steroids on the development and expression of running wheel activity and circadian rhythms in male rats

2007 ◽  
Vol 92 (5) ◽  
pp. 1010-1018 ◽  
Author(s):  
Marilyn Y. McGinnis ◽  
Augustus R. Lumia ◽  
Marc J. Tetel ◽  
Heather A. Molenda-Figueira ◽  
Bernard Possidente
2016 ◽  
Vol 21 (5) ◽  
pp. 554-561 ◽  
Author(s):  
David W. Russ ◽  
C. Acksel ◽  
K. W. McCorkle ◽  
N. K. Edens ◽  
S. M. Garvey

1968 ◽  
Vol 57 (1) ◽  
pp. 16-22 ◽  
Author(s):  
O. Linèt ◽  
V. Bumba

ABSTRACT Adult male rats were administered 19-nortestosterone phenylpropionate (NTPP), methandrostenolone (MA) (2 mg/100 g/day), cortisol (1 mg/100 g/day) and a combination of these steroids for 10 consecutive days. Cortisol caused a decrease in the adrenal weight on the 5th day and this effect was partially inhibited by NTPP or MA on the 8th and 11th day. The adrenal cholesterol content fell after NTPP on the 5th, 8th and 11th day, after cortisol treatment on the 8th and 11th day, and after MA on the 11th day. The cholesterol depleting effect of cortisol was counteracted only by simultaneous treatment with NTPP on the 11th day. The decrease in wet and dry weight of adrenals and of their nitrogen and protein content induced by the injection of cortisol for 10-days was markedly inhibited by the simultaneous administration of NTPP or MA. Neither of these anabolic-androgenic steroids affected the enhanced water retention in the adrenals caused by cortisol. NTPP or MA alone did not influence the parameters mentioned above.


1993 ◽  
Vol 265 (4) ◽  
pp. R951-R956 ◽  
Author(s):  
E. M. Thomas ◽  
M. E. Jewett ◽  
I. Zucker

We investigated the influence of ambient and body temperature (Ta and Tb) on circadian rhythms of gonadectomized male Siberian hamsters. Animals that entered torpor (Tb < 30 degrees C) had significantly shorter circadian periods (tau s) than did nontorpid hamsters at a Ta of 13 degrees C (24.17 +/- 0.05 vs. 24.33 +/- 0.04 h). The tau s of homeothermic hamsters were not affected by Ta change. Short-term decreases in Tb, rather than changes in Ta, appear to affect tau. Access to activity wheels inhibited expression of torpor in short daylengths and was associated with significant increases in body mass. Running wheel activity can mask or block specific short-day responses.


1978 ◽  
Vol 43 (2) ◽  
pp. 591-594 ◽  
Author(s):  
William P. Paré ◽  
George P. Vincent ◽  
Kile E. Isom ◽  
Jesse M. Reeves

Female rats housed in running-wheel activity cages and fed 1 hr. daily ran significantly more than similarly housed and fed male rats. Male rats survived an average of 10 days, whereas mean survival time for female rats was 7.3 days. Experimental activity rats developed glandular stomach ulcers. Pair fed controls housed in cages without activity wheels were ulcer-free. Among experimental activity rats, there were no sex differences with respect to the number or severity of ulcers.


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