Environmental enrichment alters plus maze, but not maternal defense performance in mice

2005 ◽  
Vol 85 (2) ◽  
pp. 187-194 ◽  
Author(s):  
J FRISKE ◽  
S GAMMIE
Keyword(s):  
Environmental Enrichment ◽  
Plus Maze ◽  
Maternal Defense

P.1.d.005 Effect of environmental enrichment on behaviour of mice in plus-maze tests depends on length of exposure

2006 ◽  
Vol 16 ◽  
pp. S252
Author(s):  
P. Pokk ◽  
K. Õkva ◽  
A. Lang ◽  
M. Väli ◽  
T. Nevalainen
Keyword(s):  
Environmental Enrichment ◽  
Plus Maze

Environmental Enrichment Facilitates Anxiety in Conflict-Based Tests but Inhibits Predator Threat-Induced Defensive Behaviour in Male Mice

2022 ◽  
pp. 1-12
Author(s):  
Tayllon dos Anjos-Garcia ◽  
Alexandre Kanashiro ◽  
Alline Cristina de Campos ◽  
Norberto Cysne Coimbra
Keyword(s):  
Panic Attack ◽  
Environmental Enrichment ◽  
Field Tests ◽  
Well Being ◽  
Male Mice ◽  
Defensive Strategy ◽  
Plus Maze ◽  
Marble Burying ◽  
Fear And Anxiety ◽  
Predator Threat

<b><i>Introduction:</i></b> Environmental enrichment (EE) is a useful and sophisticated tool that improves rodents’ well-being by stimulating social behaviour and cognitive, motor, and sensory functions. Exposure to EE induces neuroplasticity in different brain areas, including the limbic system, which has been implicated in the control of anxiety and fear. However, the effects of EE on ethologically relevant naturalistic behaviours, such as those displayed by prey in the presence of predators, remain largely unexplored. <b><i>Material and Methods:</i></b> In the present study, we investigated anxiety- and panic attack-like behaviours in a predator (cat)-prey confrontation paradigm and compared them with those in classical assays, such as the elevated plus-maze (EPM), marble-burying, and open field tests (OFTs), using C57BL/6J male mice housed in enriched or standard environments for 6 weeks. <b><i>Results:</i></b> We observed that EE exposure caused enhancement of the levels of anxiety-like behaviours in the EPM and OFTs, increasing risk assessment (an anxiety-related response), and decreasing escape (a panic attack-like response) behaviours during exposure to the predator versus prey confrontation paradigm. <b><i>Conclusion:</i></b> Taken together, our findings suggest that enriched external environments can modify the processing of fear- and anxiety-related stimuli in dangerous situations, changing the decision-making defensive strategy.

scholarly journals Impact of Exposure to Environmental Enrichment on the Anxiety-Like Behavior of Ovariectomized Mice

2020 ◽  
Author(s):  
Alfredo Briones-Aranda ◽  
Manuela Castellanos-Pérez ◽  
Victor Manuel Vega-Villa ◽  
Ofir Picazo
Keyword(s):  
Environmental Enrichment ◽  
Critical Role ◽  
Anxiolytic Effect ◽  
Intact Female ◽  
Short Term ◽  
Intact Male ◽  
Ovariectomized Mice ◽  
Plus Maze ◽  
Nih Swiss

Objective: The aim of this study was to explore the influence of short-term (2-week) exposure to social (SE) and/or physical enrichment (PE) on the anxiety-like behavior of ovariectomized (OVX) NIH Swiss mice. Method: One week after surgery, each OVX mouse was housed under one of 4 social conditions: (1) isolated, (2) accompanied by an intact female, (3) accompanied by an intact male, or (4) in a community of 10 OVX individuals. The animals in each of these environments were divided into 2 subgroups, consisting of the presence and absence of PE. Following a 2-week exposure to the respective conditions, each OVX mouse was subjected to either the light/dark exploration test (LDT) or the elevated plus maze (EPM) to examine anxiety-like behavior. Results: The LDT and EPM showed very similar patterns. Compared to an impoverished environment, PE elicited a significant anxiolytic effect for OVX mice housed alone or in companion of an intact female (F [1, 54] = 16.11, P = 0.001). By contrast, mice living in community but without PE displayed anxiogenic-like behavior, perhaps due to crowding, compared to the animals living in isolation (F [1, 36] = 5.64, P = 0.023). Conclusion: This study emphasized the importance of taking housing conditions into account during the screening of new anxiolytic agents and the critical role of OVX in the regulation of anxiety.

scholarly journals Environmental Enrichment Ameliorates Anxiety-Like Behavior in Rats without Altering Plasma Corticosterone Level

2021 ◽  
Vol 9 (A) ◽  
pp. 1074-1080
Author(s):  
Muthmainah Muthmainah ◽  
Winda Atika Sari ◽  
Nanang Wiyono ◽  
Dhoni Akbar Ghazali ◽  
Ratih Dewi Yudhani ◽  
...  
Keyword(s):  
Environmental Enrichment ◽  
Corticosterone Level ◽  
Anxiolytic Effect ◽  
Chronic Mild Stress ◽  
Plasma Corticosterone ◽  
Mild Stress ◽  
Environmental Interventions ◽  
Behavioral Measurement ◽  
Plus Maze ◽  
And Function

BACKGROUND: Anxiety disorder is one of the most common psychiatric problems. Prolonged stress gives rise to anxiety-like behavior in animals. Environmental interventions influence the outcome of anxiety treatment. Environmental enrichment (EE) can modulate brain’s structure and function. AIM: The objective of the study was to evaluate EE effects on anxiety-like behavior and corticosterone (CORT) level after unpredictable chronic mild stress (UCMS). METHODS: A total of 28 rats were assigned into four groups randomly: Control, UCMS, UCMS+EE, and UCMS+fluoxetine. UCMS, EE, and fluoxetine were given for 21 days. Anxiety behavior was measured on day 22nd using Elevated Plus Maze. Behavioral measurement was based on the total time spent and total entries onto open and closed arms. CORT was measured using ELISA. RESULTS: UCMS increased anxiety-like behavior as seen from reduced number of entries and time spent in open arms as well as increased number of entries and time spent in in closed arms in UCMS group than control. Rats in EE group spent more time and made more entries in the open arms than UCMS group (both p = 0.002). Anxiolytic effect of EE was stronger than fluoxetine. Plasma CORT level among groups did not differ significantly (p = 0.351). CONCLUSION: EE can ameliorate stress-induced anxiety-like behavior without affecting CORT level.

Environmental enrichment contributes to neurodevelopmental recovery after hypoxia

2009 ◽  
Author(s):  
Kathy May Tran ◽  
Madeleine Broder ◽  
Suzannah Luft ◽  
Michael L. Schwartz ◽  
Karen Muller Smith ◽  
...  
Keyword(s):  
Environmental Enrichment

Anxiolytic effects of fractions obtained from Passiflora incarnata L. in the elevated plus maze in mice

Planta Medica ◽  
2010 ◽  
Vol 76 (12) ◽  
Author(s):  
C Sampath ◽  
M Holbik ◽  
L Krenn ◽  
V Butterweck
Keyword(s):  
Elevated Plus Maze ◽  
Plus Maze ◽  
Passiflora Incarnata
Sign in / Sign up

Export Citation Format

Share Document