Running-wheel activity and body composition in golden hamsters (Mesocricetus auratus)

2004 ◽  
Vol 82 (2-3) ◽  
pp. 541-544 ◽  
Author(s):  
R GATTERMANN ◽  
R WEINANDY ◽  
P FRITZSCHE
Keyword(s):  
Body Composition ◽  
Mesocricetus Auratus ◽  
Running Wheel ◽  
Golden Hamsters ◽  
Wheel Activity

scholarly journals Topical treatment of experimental cutaneous leishmaniasis in golden hamster (Mesocricetus auratus) with formulations containing pentamidine

2017 ◽  
Vol 47 (1) ◽  
pp. 39-46 ◽  
Author(s):  
Claudia Dantas COMANDOLLI-WYREPKOWSKI ◽  
Iryna GRAFOVA ◽  
Maricleide de Farias NAIFF ◽  
Maurizio AVELLA ◽  
Gennaro GENTILE ◽  
...  
Keyword(s):  
Cutaneous Leishmaniasis ◽  
Topical Treatment ◽  
Usnic Acid ◽  
Parasite Burden ◽  
Experimental Treatment ◽  
Mesocricetus Auratus ◽  
Current Treatment ◽  
Tissue Samples ◽  
Golden Hamsters ◽  
Pentamidine Isethionate

ABSTRACT Current treatment of cutaneous leishmaniasis (CL) relies mainly on pentavalent antimonials salts and second-line drugs include pentamidine and amphotericin B, but these therapies have side effects and require parenteral administration. The aim of this work was to evaluate the topical formulations containing pentamidine isethionate (PI) in the experimental treatment of cutaneous leishmaniasis (CL). Golden hamsters (Mesocricetus auratus) were infected in the nose with Leishmania (Leishmania) amazonensis. Six treatment groups received different topical treatments of anhydrous or hydrating emulsions, for a maximum of 10 days, with an application of 50 mg day-1. After treatment tissue samples of lesions were evaluated by histology, transmission electron microscopy and biopsy cultivation. Compared with untreated group, topical treatment with hydrating emulsion with 10% PI and usnic acid (ACE5AU) showed significantly decrease in volume lesion (P= 0.028) on 20th day after the end of the treatment with reduction of 27.37%. Topical treatment with anhydrous emulsion with 10% PI and usnic acid (ACPU) reduces parasite burden in Golden hamsters. This study demonstrated the potential of topical treatment to reduce the number of parasites that could be combined with others drugs and to have a faster and more effective treatment of cutaneous leishmaniasis.

Pineal melatonin in hibernating and aroused golden hamsters (Mesocricetus auratus)

1984 ◽  
Vol 77 (4) ◽  
pp. 759-762 ◽  
Author(s):  
Jiří Vaněček ◽  
Ladislav Janský ◽  
Helena Illnerová ◽  
Klaus Hoffmann
Keyword(s):  
Mesocricetus Auratus ◽  
Pineal Melatonin ◽  
Golden Hamsters

scholarly journals Evaluation of the Anti Chagas "PF" Vaccine Against two Strains of Leishmania sp. in Hamsters ()

1976 ◽  
Vol 6 (4) ◽  
pp. 483-485
Author(s):  
Jorge R. Arias ◽  
Humberto Menezes ◽  
Rui A. de Freitas
Keyword(s):  
Mesocricetus Auratus ◽  
Golden Hamsters ◽  
Significant Difference

Abstract Amastigotes of two strains of Leishmania sp. were innoculated into golden hamsters (Mesocricetus auratus) 8 and 15 days after innoculation with the anti-chagas "PF" vaccine. There was no significant difference in reduction of infection between the "PF" treated and the control (untreated) hamsters after innoculations with either strain of Leishmania sp.

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