Role of Gallium in the charge transport mechanisms for La0.67Ca0.33Mn1–xGaxO3 manganites

2018 ◽  
Vol 545 ◽  
pp. 182-189 ◽  
Author(s):  
B.R. Kataria ◽  
Ashish Ravalia ◽  
A.U. Vyas ◽  
D.D. Pandya ◽  
P.S. Solanki ◽  
...  
2018 ◽  
Vol 541 ◽  
pp. 43-49 ◽  
Author(s):  
B.R. Kataria ◽  
Pankaj Solanki ◽  
D.D. Pandya ◽  
P.S. Solanki ◽  
N.A. Shah

2005 ◽  
Vol 39 (3) ◽  
pp. 331-335
Author(s):  
G. A. Il’chuk ◽  
S. E. Nikitin ◽  
Yu. A. Nikolaev ◽  
V. Yu. Rud’ ◽  
Yu. V. Rud’ ◽  
...  

Langmuir ◽  
2008 ◽  
Vol 24 (5) ◽  
pp. 2219-2223 ◽  
Author(s):  
Yabing Qi ◽  
Imma Ratera ◽  
Jeong Y. Park ◽  
Paul D. Ashby ◽  
Su Ying Quek ◽  
...  

2012 ◽  
Vol 101 (24) ◽  
pp. 243302 ◽  
Author(s):  
Yasuhiro Mashiko ◽  
Dai Taguchi ◽  
Martin Weis ◽  
Takaaki Manaka ◽  
Mitsumasa Iwamoto

Author(s):  
Jussi T. Koivumäki ◽  
Jouni Takalo ◽  
Topi Korhonen ◽  
Pasi Tavi ◽  
Matti Weckström

When developing large-scale mathematical models of physiology, some reduction in complexity is necessarily required to maintain computational efficiency. A prime example of such an intricate cell is the cardiac myocyte. For the predictive power of the cardiomyocyte models, it is vital to accurately describe the calcium transport mechanisms, since they essentially link the electrical activation to contractility. The removal of calcium from the cytoplasm takes place mainly by the Na + /Ca 2+ exchanger, and the sarcoplasmic reticulum Ca 2+ ATPase (SERCA). In the present study, we review the properties of SERCA, its frequency-dependent and β -adrenergic regulation, and the approaches of mathematical modelling that have been used to investigate its function. Furthermore, we present novel theoretical considerations that might prove useful for the elucidation of the role of SERCA in cardiac function, achieving a reduction in model complexity, but at the same time retaining the central aspects of its function. Our results indicate that to faithfully predict the physiological properties of SERCA, we should take into account the calcium-buffering effect and reversible function of the pump. This ‘uncomplicated’ modelling approach could be useful to other similar transport mechanisms as well.


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