Modeling of magnetic material displaying magnetic aftereffect with slow decay rates

2012 ◽  
Vol 407 (9) ◽  
pp. 1372-1376 ◽  
Author(s):  
S. Gu ◽  
Y. Jin ◽  
P. Chen ◽  
C. Yan ◽  
E. Della Torre ◽  
...  
Keyword(s):  
Magnetic Material ◽  
Decay Rates ◽  
Slow Decay ◽  
Magnetic Aftereffect

Direct photoionization measurements of slow decay rates of vibrationally overexcited (CF3)3CI molecules in the ground electronic state in a beam

1986 ◽  
Vol 127 (5) ◽  
pp. 438-444 ◽  
Author(s):  
V.M. Apatin ◽  
V.S. Letokhov ◽  
V.N. Lokhman ◽  
G.N. Makarov ◽  
V.N. Bagratashvili ◽  
...  
Keyword(s):  
Electronic State ◽  
Decay Rates ◽  
Ground Electronic State ◽  
Slow Decay

scholarly journals Dynamics of latent HIV under clonal expansion

2021 ◽  
Vol 17 (12) ◽  
pp. e1010165
Author(s):  
John M. Murray
Keyword(s):  
Half Life ◽  
Maximum Size ◽  
Decay Rates ◽  
Latent Reservoir ◽  
Homeostatic Proliferation ◽  
Art Initiation ◽  
Slow Decay ◽  
Latent Hiv ◽  
The Individual ◽  
Integration Data

The HIV latent reservoir exhibits slow decay on antiretroviral therapy (ART), impacted by homeostatic proliferation and activation. How these processes contribute to the total dynamic while also producing the observed profile of sampled latent clone sizes is unclear. An agent-based model was developed that tracks individual latent clones, incorporating homeostatic proliferation of cells and activation of clones. The model was calibrated to produce observed latent reservoir dynamics as well as observed clonal size profiles. Simulations were compared to previously published latent HIV integration data from 5 adults and 3 children. The model simulations reproduced reservoir dynamics as well as generating residual plasma viremia levels (pVL) consistent with observations on ART. Over 382 Latin Hypercube Sample simulations, the median latent reservoir grew by only 0.3 log10 over the 10 years prior to ART initiation, after which time it decreased with a half-life of 15 years, despite number of clones decreasing at a faster rate. Activation produced a maximum size of genetically intact clones of around one million cells. The individual simulation that best reproduced the sampled clone profile, produced a reservoir that decayed with a 13.9 year half-life and where pVL, produced mainly from proliferation, decayed with a half-life of 10.8 years. These slow decay rates were achieved with mean cell life-spans of only 14.2 months, due to expansion of the reservoir through proliferation and activation. Although the reservoir decayed on ART, a number of clones increased in size more than 4,000-fold. While small sampled clones may have expanded through proliferation, the large sizes exclusively arose from activation. Simulations where homeostatic proliferation contributed more to pVL than activation, produced pVL that was less variable over time and exhibited fewer viral blips. While homeostatic proliferation adds to the latent reservoir, activation can both add and remove latent cells. Latent activation can produce large clones, where these may have been seeded much earlier than when first sampled. Elimination of the reservoir is complicated by expanding clones whose dynamic differ considerably to that of the entire reservoir.

scholarly journals Random mutagenesis of bacterial luciferase: critical role of Glu175 in the control of luminescence decay

2005 ◽  
Vol 385 (2) ◽  
pp. 575-580 ◽  
Author(s):  
Saman HOSSEINKHANI ◽  
Rose SZITTNER ◽  
Edward A. MEIGHEN
Keyword(s):  
Decay Rate ◽  
Random Mutagenesis ◽  
Luminescence Decay ◽  
Decay Rates ◽  
Single Mutation ◽  
Fast Decay ◽  
Rapid Decay ◽  
Slow Decay ◽  
Critical Residue

Bacterial luciferases (LuxAB) can be readily classed as slow or fast decay luciferases based on their rates of luminescence decay in a single turnover assay. Luciferases from Vibrio harveyi and Xenorhabdus (Photorhabdus) luminescens have slow decay rates, and those from the Photobacterium genus, such as Photobacterium fisheri, P. phosphoreum and P. leiognathi, have rapid decay rates. By substitution of a 67-amino-acid stretch of P. phosphoreum LuxA in the central region of the LuxA subunit, the ‘slow’ X. luminescens luciferase was converted into a chimaeric luciferase with a significantly more rapid decay rate [Valkova, Szittner and Meighen (1999) Biochemistry 38, 13820–13828]. To understand better the role of specific residues in the classification of luciferases as slow and fast decay, we have conducted random mutagenesis on this region. One of the mutants generated by a single mutation on LuxA at position 175 [E175G (Glu175→Gly)] resulted in the ‘slow decay’ X. luminescens luciferase being converted into a luciferase with a significantly more rapid decay rate. These results indicate the importance of Glu175 in LuxA as a critical residue for differentiating between ‘slow’ and ‘fast’ luciferases and show that this distinction is primarily due to differences in aldehyde affinity and in the decomposition of the luciferase–flavin–oxygen intermediate.

Magnetic Material Observation Assembly for Tem with a Eucentric Goniometer

1976 ◽  
Vol 34 ◽  
pp. 540-541
Author(s):  
K. Shi rota ◽  
A. Yonezawa ◽  
K. Shibatomi ◽  
T. Yanaka
Keyword(s):  
Magnetic Material ◽  
Electron Microscope ◽  
Magnetic Domain ◽  
Objective Lens ◽  
Magnetic Domains ◽  
Lorentz Microscopy ◽  
Transmission Electron ◽  
Correction Of Astigmatism ◽  
Single Orientation ◽  
Conventional Transmission Electron Microscope

As is well known, it is not so easy to operate a conventional transmission electron microscope for observation of magnetic materials. The reason is that the instrument requires re-alignment of the axis and re-correction of astigmatism after each specimen shift, as the lens field is greatly disturbed by the specimen. With a conventional electron microscope, furthermore, it is impossible to observe magnetic domains, because the specimen is magnetized to single orientation by the lens field. The above mentioned facts are due to the specimen usually being in the lens field. Thus, special techniques or systems are usually required for magnetic material observation (especially magnetic domain observation), for example, the technique to switch off the objective lens current and Lorentz microscopy. But these cannot give high image quality and wide magnification range, and furthermore Lorentz microscopy is very complicated.

Magnetic Aftereffect and Magnetization Reversal of Sr-Ferrite Fine Particles.

1994 ◽  
Vol 18 (2) ◽  
pp. 193-196 ◽  
Author(s):  
H. Nishio ◽  
H. Taguchi ◽  
F. Hirata ◽  
T. Takeishi
Keyword(s):  
Magnetization Reversal ◽  
Fine Particles ◽  
Magnetic Aftereffect

Development of Magnetic Material for Low Loss

2019 ◽  
Vol 139 (2) ◽  
pp. 84-87
Author(s):  
Kentaro MORI ◽  
Masahiko WATANABE
Keyword(s):  
Magnetic Material ◽  
Low Loss

Comparison of decay rates of faecal indicator organisms in recreational coastal water and sediment

2002 ◽  
Vol 2 (3) ◽  
pp. 131-138 ◽  
Author(s):  
D.L. Craig ◽  
H.J. Fallowfield ◽  
N.J. Cromar
Keyword(s):  
Water Column ◽  
Coastal Water ◽  
Decay Rates ◽  
Organic Carbon Content ◽  
Indicator Organisms ◽  
Filtration Method ◽  
E Coli ◽  
Water And Sediment ◽  
Increased Risk ◽  
High Organic Carbon Content

A laboratory based microcosm study utilising intact non-sterile sediment cores was undertaken to determine the survival of the faecal indicator organisms Escherichia coli, Enterococcus faecium and somatic coliphage in both recreational coastal water and sediment. Overlying water was inoculated with the test organisms and incubated at 10°C, 20°C or 30°C. E. coli, enterococcus and coliphage were enumerated from the water column and sediment by the membrane filtration method, Enterolert (IDEXX Laboratories) and the double-agar overlay methods respectively on days 0, 1, 2, 7, 14 and 28 following inoculation. It was demonstrated that for all organisms, greater decay (k; d-1) occurred in the water column compared to sediment. Sediment characteristics were found to influence decay, with lowest decay rates observed in sediment consisting of high organic carbon content and small particle size. Decay of E. coli was significantly greater in both the water column and sediment compared with enterococcus and coliphage under all conditions. Decay of enterococcus was found to closely resemble that of coliphage decay. Survival of all organisms was inversely related to temperature, with greatest decay at 30°C. However, increased temperature had a less significant impact on survival of enterococcus and coliphage compared with E. coli. The importance of this study for estimating risk from recreational exposure is great if some pathogenic microorganisms behave similarly to the organisms tested in this study. In particular if survival rates of pathogens are similar to enterococcus and coliphage, then their ability to accumulate in coastal sediment may lead to an increased risk of exposure if these organisms are resuspended into the water column due to natural turbulence or human recreational activity.

Nitrate and chloride formation in chloramination

1994 ◽  
Vol 30 (9) ◽  
pp. 101-110
Author(s):  
V. Diyamandoglu
Keyword(s):  
Kinetic Model ◽  
Analytical Method ◽  
Kinetic Data ◽  
Experimental Results ◽  
Mass Balances ◽  
Time Profiles ◽  
Slow Decay ◽  
Concentration Time ◽  
End Products ◽  
Chlorine Residuals

The formation of nitrate and chloride as end-products of chloramination (combined chlorination) was investigated at pH ranging between 6.9 and 9.6 at 25°C. The experimental results comprised concentration-time profiles of combined chlorine residuals along with nitrate and chloride. Nitrite, if present, was always below the detectibility limit of the analytical method used (25 ppb). Mass balances on chlorine species depicted that chloride formed during the slow decay of combined chlorine residuals does not account for all the chlorine lost. This substantiates the formation of other reaction end-products which are yet to be identified. A kinetic model for chloramination is proposed based on the kinetic data obtained in this study.

Sign in / Sign up

Export Citation Format

Share Document