Using fitting functions to estimate the diffusion coefficient of drug molecules in diffusion-controlled release systems

2021 ◽  
Vol 567 ◽  
pp. 125681
Author(s):  
M. Ignacio ◽  
G.W. Slater
Keyword(s):  
Diffusion Coefficient ◽  
Controlled Release ◽  
Drug Molecules ◽  
Diffusion Controlled

Synthesis, characterization and drug release studies of poly(2-hydroxyethyl methacrylate)/KIT-5 nanocomposite as an innovative organic–inorganic hybrid carrier system

RSC Advances ◽  
2015 ◽  
Vol 5 (16) ◽  
pp. 12463-12471 ◽  
Author(s):  
Roozbeh Javad Kalbasi ◽  
Ali Zirakbash
Keyword(s):  
Controlled Release ◽  
Drug Release ◽  
Hybrid Material ◽  
Great Promise ◽  
Hydroxyethyl Methacrylate ◽  
Carrier System ◽  
Inorganic Hybrid ◽  
Drug Molecules ◽  
System P ◽  
Release Studies

PHEMA/KIT-5 with various pore sizes was prepared. Efficient encapsulation of drug molecules inside the pores of the hybrid material and controlled release of them in an aqueous medium, suggest the great promise of the composite as a carrier system.

scholarly journals Phosphonium hydrogels for controlled release of ionic cargo

2018 ◽  
Vol 54 (79) ◽  
pp. 11164-11167 ◽  
Author(s):  
Tristan D. Harrison ◽  
Paul J. Ragogna ◽  
Elizabeth R. Gillies
Keyword(s):  
Controlled Release ◽  
Drug Molecules ◽  
Phosphonium Cations

Hydrogels containing phosphonium cations were synthesized and demonstrated to electrostatically bind and release anionic drug molecules depending on their structures.

CONTROLLED RELEASE OF IMIDACLOPRID FROM POLY (STYRENE–DIACETONE CRYLAMIDE)-BASED NANOFORMULATION

2012 ◽  
Vol 11 (06) ◽  
pp. 1240036 ◽  
Author(s):  
KUN QIAN ◽  
YANZHEN GUO ◽  
LIN HE
Keyword(s):  
Controlled Release ◽  
Environmental Pollution ◽  
Active Ingredient ◽  
Release Formulation ◽  
Effective Utilization ◽  
Loading Efficiency ◽  
Diffusion Controlled ◽  
Controlled Release Formulations ◽  
Higher Temperature ◽  
Potential Interactions

Imidacloprid is a neonicotinoids insecticide, which is important for the cash crops such as tomato, rape and so on. The conventional formulation does not only increase the loss of pesticide but also leads to environmental pollution. Controlled-release formulations of pesticide are highly desirable not only for attaining the most effective utilization of the pesticide, but also for reducing environmental pollution. Pesticide imidacloprid was incorporated in poly (styrene–diacetone crylamide)-based formulation to obtain controlled release properties, and the imidacloprid nanocontrolled release formulation was characterized by infrared (IR) and field emission scanning electron microscope (FESEM). Factors related to loading efficiency, swelling and release behaviors of the formulation were investigated. It showed that the loading efficiency could reach about 40% (w/w). The values for the diffusion exponent "n" were in the range of 0.31–0.58, which indicated that the release of imidacloprid was diffusion-controlled. The time taken for 50% of the active ingredient to be released into water, T50, was also calculated for the comparison of formulations in different conditions. The results showed that the formulation with higher temperature and more diacetone crylamide had lower value of T50, which means a quicker release of the active ingredient. This study highlighted some pieces of evidence that improved pesticide incorporation and slower release were linked to potential interactions between the pesticide and the polymer.

Analysis of diffusion controlled release of hydrogen from nickel and inconel 600

1989 ◽  
Vol 37 (7) ◽  
pp. 1913-1921 ◽  
Author(s):  
P. Shewmon ◽  
Y.L. Shen ◽  
C.H. Shen ◽  
M. Meshii
Keyword(s):  
Controlled Release ◽  
Inconel 600 ◽  
Diffusion Controlled

Modeling the Diffusion Mechanism and the Reaction Kinetics for the Photocatalytic Degradation of Acid Red 151 Aqueous Solutions by ZnO: Comparison of Linear and Non-Linear Methods

2007 ◽  
Vol 10 (2) ◽  
Author(s):  
K. Vasanth Kumar ◽  
K. Porkodi
Keyword(s):  
Aqueous Solution ◽  
Diffusion Coefficient ◽  
Aqueous Solutions ◽  
Photocatalytic Degradation ◽  
Reaction Kinetics ◽  
Diffusion Mechanism ◽  
Batch Processes ◽  
Average Diffusion Coefficient ◽  
Diffusion Controlled ◽  
Average Diffusion

AbstractBatch processes were carried out for the photocatalytic degradation of Acid Red 151 from its aqueous solution using ZnO catalyst at different initial dye concentrations. The process was found to be diffusion controlled for the first 15-20 minutes (before irradiation) with an average diffusion coefficient of 6.759 × 10

Controlled release of drug molecules in metal–organic framework material HKUST-1

2017 ◽  
Vol 79 ◽  
pp. 78-81 ◽  
Author(s):  
Qing Chen ◽  
Qi-Wei Chen ◽  
Chong Zhuang ◽  
Piao-Ping Tang ◽  
Ning Lin ◽  
...  
Keyword(s):  
Controlled Release ◽  
Metal Organic Framework ◽  
Drug Molecules ◽  
Metal Organic ◽  
Organic Framework

scholarly journals The Kinetics of Joined Action of Triplet-Triplet Annihilation and First-Order Decay of Molecules in T1State in the Case of Nondominant First-Order Process: The Kinetic Model in the Case of Spatially Periodic Excitation

2013 ◽  
Vol 2013 ◽  
pp. 1-16 ◽  
Author(s):  
Paweł Borowicz ◽  
Bernhard Nickel
Keyword(s):  
Diffusion Coefficient ◽  
Kinetic Model ◽  
Periodic Pattern ◽  
Constructive Interference ◽  
First Order ◽  
Dependent Rate ◽  
Diffusion Controlled ◽  
Spatially Periodic ◽  
Kinetics Of ◽  
Triplet Triplet Annihilation

In this paper the model developed for estimation of the diffusion coefficient of the molecules in the triplet state is presented. The model is based on the intuitive modification of the Smoluchowski equation for the time-dependent rate parameter. Since the sample is irradiated with the spatially periodic pattern nonexponential effects can be expected in the areas of the constructive interference of the exciting laser beams. This nonexponential effects introduce changes in the observed kinetics of the diffusion-controlled triplet-triplet annihilation. Due to irradiation with so-called long excitation pulse these non-exponential effects are very weak, so they can be described with introducing very simple correction to the kinetic model described in the first paper of this series. The values of diffusion coefficient of anthracene are used to calculate the annihilation radius from the data for spatially homogeneous excitation.

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