Antifungal activity of Coriandrum sativum essential oil, its mode of action against Candida species and potential synergism with amphotericin B

Phytomedicine ◽  
2011 ◽  
Vol 19 (1) ◽  
pp. 42-47 ◽  
Author(s):  
Filomena Silva ◽  
Susana Ferreira ◽  
Andreia Duarte ◽  
Dina I. Mendonça ◽  
Fernanda C. Domingues
PLoS ONE ◽  
2014 ◽  
Vol 9 (6) ◽  
pp. e99086 ◽  
Author(s):  
Irlan de Almeida Freires ◽  
Ramiro Mendonça Murata ◽  
Vivian Fernandes Furletti ◽  
Adilson Sartoratto ◽  
Severino Matias de Alencar ◽  
...  

Molecules ◽  
2012 ◽  
Vol 17 (7) ◽  
pp. 8439-8448 ◽  
Author(s):  
Bruna V. Soares ◽  
Selene M. Morais ◽  
Raquel Oliveira dos Santos Fontenelle ◽  
Vanessa A. Queiroz ◽  
Nadja S. Vila-Nova ◽  
...  

2011 ◽  
Vol 60 (10) ◽  
pp. 1479-1486 ◽  
Author(s):  
Filomena Silva ◽  
Susana Ferreira ◽  
João A. Queiroz ◽  
Fernanda C. Domingues

2020 ◽  
Vol 32 (3) ◽  
pp. 167
Author(s):  
Bernadya Yogatri Anjuwita ◽  
Iskandar Zulkarnain ◽  
Muhammad Yulianto Listiawan ◽  
Evy Ervianti ◽  
Rahmadewi Rahmadewi ◽  
...  

Background: Oral candidiasis is caused by the mycotic activity of Candida albicans present in the oral cavity, and it is one of the most common opportunistic infections found in patients with Human Immunodeficiency Virus (HIV)/acquired immune deficiency syndrome (AIDS). The growing resistance and side effects to common antifungal drugs have promoted herbal essential oils as antifungal agents in recent years. In this study, essential oils (EO) of Rosmarinus officinalis (Lamiaceae) were examined for in vitro antifungal activ­ity against Candida species. Purpose: To evaluate the antifungal activity of essential oils of Rosmarinus officinalis (Lamiaceae) and nystatin using the microdilution technique by determining the minimum inhibitory concentration (MIC) and the minimum fungicidal concentration (MFC) of Candida spesies. Methods: This was an experimental laboratory study with a post-test-only design conducted in Dr. Soetomo General Academic Teaching Hospital, Surabaya. Forty isolates consisted of twenty isolates of Candida albicans and twenty isolates of Candida non-albicans were collected. The isolates were tested for antifungal activity using the microdilution on 96-well plates. Result: There was a significant difference from the results of the MIC concentration of rosemary essential 100% to 6.25% microdilution method between nystatin and rosemary essential oil (p < 0.05). Conclusion: The antifungal activity of rosemary essential oil was better than nystatin that the lowest MIC value, which was 6.25%, has been obtained the microdilution method. The minimum fungicidal concentration of rosemary essential oil was 25%, while the minimum fungicidal concentration nystatin was higher than 100%.


Mycoses ◽  
2011 ◽  
Vol 54 (6) ◽  
pp. e737-e743 ◽  
Author(s):  
László Galgóczy ◽  
Andrea Bácsi ◽  
Mónika Homa ◽  
Máté Virágh ◽  
Tamás Papp ◽  
...  

2019 ◽  
Author(s):  
L Risaliti ◽  
G Pini ◽  
R Donato ◽  
C Sacco ◽  
A Roberta ◽  
...  

Author(s):  
Paula Mariane Silva Sousa ◽  
Jefferson Rodrigues Nóbrega ◽  
Laísa Vilar Cordeiro ◽  
Francisco Patricio De Andrade Júnio ◽  
Wylly Araújo de Oliveira

The objective was evaluating the antifungal activity of ibuprofen alone and when associated with amphotericin B or ketoconazole against Candida species. Strains of C. albicans, C. tropicalis, C. guilliermondii, C. krusei and C. parapsilosis were used. The minimum inhibitory concentration (MIC) was determined by the microdilution method and the association study performed through the checkerboard assay. The concentration of 512 µg/mL inhibited approximately 65% of the tested strains, while against 35% of the strains presented MIC values above 2048 µg/mL. Associations of ibuprofen with amphotericin B against C. tropicalis and ibuprofen with ketoconazole against C. krusei showed synergistic effect. Antagonistic effects were evidenced in the combination of ibuprofen with amphotericin B against C. guilliermondii and C. albicans, as well as in the association of ibuprofen with ketoconazole against C. albicans and C. tropicalis. Through the experiments, it was found that ibuprofen showed antifungal activity against most of the Candida species tested. The combinations of ibuprofen and antifungals had synergistic effects. However, antagonistic results were evidenced in the association with ibuprofen, which would make clinical applicability difficult. Therefore, studies of this combined activity should be investigated, considering that this association may be positive for antifungal therapy.


Mycoses ◽  
2007 ◽  
Vol 50 (5) ◽  
pp. 403-406 ◽  
Author(s):  
Kamel Chaieb ◽  
Tarek Zmantar ◽  
Riadh Ksouri ◽  
Hafedh Hajlaoui ◽  
Kacem Mahdouani ◽  
...  

Author(s):  
Ricardo Dias de Castro ◽  
Trícia Murielly Pereira Andrade de Souza ◽  
Louise Morais Dornelas Bezerra ◽  
Gabriela Lacet Silva Ferreira ◽  
Edja Maria Melo de Brito Costa ◽  
...  

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