A galactosamine-mediated drug delivery carrier for targeted liver cancer therapy

2011 ◽  
Vol 64 (4) ◽  
pp. 410-419 ◽  
Author(s):  
Zheyu Shen ◽  
Wei Wei ◽  
Hideyuki Tanaka ◽  
Kazuhiro Kohama ◽  
Guanghui Ma ◽  
...  
2018 ◽  
Vol 2018 ◽  
pp. 1-11
Author(s):  
Huiling Lv ◽  
Chao Wu ◽  
Xuan Liu ◽  
Andi Bai ◽  
Yue Cao ◽  
...  

In this study, we prepared PTX-loaded mesoporous hollow SnO2 nanofibers conjugated with folic acid (SFNFP) for liver cancer therapy. According to SEM and TEM characterization, SFNF showed a mesoporous hollow structure. The average outer diameter was 200 nm, and the wall thickness was 50 nm. The DSC and XRD study showed that PTX in the channels of nanofibers was present in an amorphous state. The in vitro release experiments demonstrated that SFNF could efficiently improve the dissolution rate of PTX. Both in vitro cell experiments and in vivo antitumor experiments showed that SFNFP could efficiently inhibit the growth of liver cancer cells. Therefore, SFNF is a promising targeting antitumor drug delivery carrier.


2011 ◽  
Vol 21 (14) ◽  
pp. 5299 ◽  
Author(s):  
Tingting Wang ◽  
Fang Chai ◽  
Qin Fu ◽  
Lingyu Zhang ◽  
Haiyan Liu ◽  
...  

2019 ◽  
Vol 95 ◽  
pp. 328-341 ◽  
Author(s):  
María J. Limeres ◽  
Marcela A. Moretton ◽  
Ezequiel Bernabeu ◽  
Diego A. Chiappetta ◽  
María L. Cuestas

Author(s):  
Bei Li ◽  
Lan Sun ◽  
Tao Li ◽  
Yingge Zhang ◽  
Xiao Ya Niu ◽  
...  

Gold nanomaterials are widely used in biomedical research as drug delivery systems, imaging agents and therapeutic materials owing to their unique physicochemical properties and high biocompatibility. In this study, we...


Drug Delivery ◽  
2021 ◽  
Vol 29 (1) ◽  
pp. 138-148
Author(s):  
Xue Liu ◽  
Zhenfeng Wu ◽  
Chunjing Guo ◽  
Huimin Guo ◽  
Yanguo Su ◽  
...  

2014 ◽  
Vol 2 (9) ◽  
pp. 1262-1274 ◽  
Author(s):  
Wei Tao ◽  
Xiaowei Zeng ◽  
Jinxie Zhang ◽  
Huijun Zhu ◽  
Danfeng Chang ◽  
...  

DTX-loaded CA-(PCL-ran-PLA)-b-PEG1k NPs were prepared and shown great potential as drug delivery nanocarriers for cancer therapy.


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