scholarly journals Anti-inflammatory effects of the essential oils of ginger (Zingiber officinale Roscoe) in experimental rheumatoid arthritis

2016 ◽  
Vol 4 (3) ◽  
pp. 123-131 ◽  
Author(s):  
Janet L. Funk ◽  
Jennifer B. Frye ◽  
Janice N. Oyarzo ◽  
Jianling Chen ◽  
Huaping Zhang ◽  
...  
Keyword(s):  
Rheumatoid Arthritis ◽  
Essential Oils ◽  
Zingiber Officinale ◽  
Zingiber Officinale Roscoe ◽  
Anti Inflammatory

scholarly journals Zanjabeel (Zingiber officinale Roscoe.): An Evidence-Based Review of Anti-nociceptive, Anti-inflammatory, Antioxidant, and Antimicrobial Properties

2021 ◽  
pp. 26-35
Author(s):  
Fatima Khan ◽  
Mohd Nayab ◽  
Abdul Nasir Ansari
Keyword(s):  
Therapeutic Potential ◽  
Antioxidant Properties ◽  
Plant Secondary Metabolites ◽  
Zingiber Officinale ◽  
Extensive Study ◽  
The Body ◽  
Wide Range ◽  
Zingiber Officinale Roscoe ◽  
Medicinal Properties ◽  
Anti Inflammatory

Ginger has been appreciated for over 2500-3000 years in many parts of the world due to its numerous scientific properties. The ginger plant (Zingiber officinale Roscoe) belongs to the Zingiberaceae family. It is a known food and flavoring ingredient reputed for its wide range of medicinal properties that have been widely used in Chinese, Ayurvedic, and Unāni Tibb worldwide, since antiquity. Ginger has long been used to cure a variety of ailments, including diarrhea, stomach discomfort, indigestion, and nausea. It is a versatile herb with phenomenal phytotherapeutic and medicinal properties. Active ingredients available in ginger such as 6-gingerol, 6-shogaol, 6-paradol, and zingerone are responsible for upgrading enzyme actions and balancing circulation through rejuvenating the body with physical re-strengthening. Gingerols, the key phenolic plant secondary metabolites responsible for its distinct flavor and health benefits, are found in the rhizome of ginger Extensive study has been undertaken over the last two decades to uncover bioactive ingredients and the therapeutic potential of ginger. This review considers ginger's chemical composition and the most recent study findings on its possible health advantages, such as analgesic, anti-inflammatory, antibacterial, and antioxidant properties due to its phytochemistry. Overall, clinical trials are needed to confirm these prospective various health advantages of ginger in human subjects and the most efficacious dosage, based on the current body of scientific literature.

scholarly journals Effect of Essential Oils from Ginger (Zingiber officinale) and Turmeric (Curcuma longa) Rhizomes on Some Inflammatory Biomarkers in Cadmium Induced Neurotoxicity in Rats

2018 ◽  
Vol 2018 ◽  
pp. 1-7 ◽  
Author(s):  
Ayodele Jacob Akinyemi ◽  
Philip Adeyemi Adeniyi
Keyword(s):  
Prefrontal Cortex ◽  
Essential Oil ◽  
Essential Oils ◽  
Neurological Diseases ◽  
Curcuma Longa ◽  
Zingiber Officinale ◽  
Inflammatory Biomarkers ◽  
Tnf Alpha ◽  
Anti Inflammatory ◽  
Inflammatory Effect

Studies have revealed that anti-inflammatory agents could provide beneficial effect in lowering the incidence/progression of neurological diseases. Hence, this study sought to investigate the effect of essential oils from Nigeria ginger and turmeric rhizomes on some cytokines in cadmium induced neurotoxicity. The result revealed that essential oil from ginger and turmeric rhizomes exerts anti-inflammatory effect by preventing alterations of some cytokines/inflammatory biomarkers (IL-6, IL-10 and TNF-Alpha) levels and inhibits both hippocampus and prefrontal cortex acetylcholinesterase (AChE) and adenosine deaminase (ADA) activities (important enzymes relevant in the management/prevention of neurodegenerative diseases) in Cd treated rats. In conclusion, essential oil from ginger and turmeric rhizomes exerts anti-inflammatory properties in Cd induced neurotoxicity. The observed effect could be due to the volatile compounds as revealed by GC-MS analysis.

scholarly journals USAGE OF ESSENTIAL OILS OF BASIL (Ocimum basilicum L.) AND GINGER (Zingiber officinale Roscoe) FOR FLAVORING OLIVE OIL

Nucleus ◽  
2017 ◽  
Vol 14 (1) ◽  
pp. 189-196
Author(s):  
Patrícia Fontes Pinheiro ◽  
Bianca Viguini Chaves ◽  
Pollyanna Ibrahim Silva ◽  
Suzana Maria DELLA LUCIA ◽  
Sérgio Henriques Saraiva ◽  
...  
Keyword(s):  
Essential Oils ◽  
Olive Oil ◽  
Zingiber Officinale ◽  
Ocimum Basilicum ◽  
Zingiber Officinale Roscoe

scholarly journals Chemical composition and in vitro biological activities of the essential oils of the rhizomes of Zingiber officinale Roscoe and Curcuma longa L. (Zingiberaceae)

2020 ◽  
Vol 6 (4) ◽  
pp. 17766-17772
Author(s):  
Cicera Janaine Camilo ◽  
Natália Kelly Gomes Carvalho ◽  
Carla de Fatima Alves Nonato ◽  
Débora Odília Duarte Leite ◽  
Alexandro Rodrigues Dantas ◽  
...  
Keyword(s):  
Chemical Composition ◽  
Essential Oils ◽  
Biological Activities ◽  
Curcuma Longa ◽  
Zingiber Officinale ◽  
Zingiber Officinale Roscoe

scholarly journals Benefits of Ginger and Its Constituent 6-Shogaol in Inhibiting Inflammatory Processes

2021 ◽  
Vol 14 (6) ◽  
pp. 571
Author(s):  
Iris Bischoff-Kont ◽  
Robert Fürst
Keyword(s):  
Zingiber Officinale ◽  
Mapk Signaling ◽  
Ppar Γ ◽  
Mediator Systems ◽  
Zingiber Officinale Roscoe ◽  
Ginger Rhizome ◽  
Inflammatory Processes ◽  
Anti Inflammatory

Ginger (Zingiber officinale Roscoe) is widely used as medicinal plant. According to the Committee on Herbal Medicinal Products (HMPC), dried powdered ginger rhizome can be applied for the prevention of nausea and vomiting in motion sickness (well-established use). Beyond this, a plethora of pre-clinical studies demonstrated anti-cancer, anti-oxidative, or anti-inflammatory actions. 6-Shogaol is formed from 6-gingerol by dehydration and represents one of the main bioactive principles in dried ginger rhizomes. 6-Shogaol is characterized by a Michael acceptor moiety being reactive with nucleophiles. This review intends to compile important findings on the actions of 6-shogaol as an anti-inflammatory compound: in vivo, 6-shogaol inhibited leukocyte infiltration into inflamed tissue accompanied with reduction of edema swelling. In vitro and in vivo, 6-shogaol reduced inflammatory mediator systems such as COX-2 or iNOS, affected NFκB and MAPK signaling, and increased levels of cytoprotective HO-1. Interestingly, certain in vitro studies provided deeper mechanistic insights demonstrating the involvement of PPAR-γ, JNK/Nrf2, p38/HO-1, and NFκB in the anti-inflammatory actions of the compound. Although these studies provide promising evidence that 6-shogaol can be classified as an anti-inflammatory substance, the exact mechanism of action remains to be elucidated. Moreover, conclusive clinical data for anti-inflammatory actions of 6-shogaol are largely lacking.

scholarly journals Antioxidant and Anticancer Activities of Anethum graveolens L., Citrus limon (L.) Osbeck and Zingiber officinale Roscoe Essential Oils

2022 ◽  
Author(s):  
Mahmoud Osanloo ◽  
Ali Ghanbariasad ◽  
Ali Taghinezhad
Keyword(s):  
Essential Oils ◽  
Antioxidant Activities ◽  
Zingiber Officinale ◽  
Gas Chromatography Mass Spectrometry ◽  
Breast Cancer Cell Lines ◽  
Citrus Limon ◽  
Anethum Graveolens ◽  
Anticancer Activities ◽  
Zingiber Officinale Roscoe ◽  
Mcf 7

Since synthetic chemotherapeutic drugs produce a certain degree of drug resistance and due to their common side effects, such as damage to hematopoietic cells and hair loss, it is necessary to use herbal medicine as a substrate to develop new anticancer drugs. The ingredients of three essential oils (EO) were identified using gas chromatography–mass spectrometry (GC-MS) analysis. Their anticancer activities have been investigated on four human breast cancer cell lines, including MCF-7, MDA-MB-175, MDA-MB-231, and MDA-MB-468. In addition, their antioxidant activity was evaluated using the 2,2-diphenyl-1-picrylhydrazyl (DPPH) assay. The three plants were investigated for identifications of the ingredients of their EOs, and major ingredients were identified in each plant as alpha-phellandrene (26.75 %) in Anethum graveolens L., limonene (61.83 %) in Citrus limon (L.) Osbeck, and zingiberene (30.28 %) in Zingiber officinale Roscoe. Among the EOs, C. limon was significantly more effective than others; its half-maximal inhibitory concentration (IC50) on MCF-7 was obtained at 201 µg.mL-1. Furthermore, Z. officinale EO showed a higher antioxidant activities in comparison to the two other EOs. Considering the antioxidant and anticancer effects of the EOs, they could be further investigated as a possible complementary medicine in cancer.

scholarly journals GAMBARAN KARAKTERISTIK RESPONDEN RHEUMATOID ARTHRITIS PRE TREATMENT GINGER OIL (Zingiber Officinale Rosc) DAN TERAPI RESISTED ACTIVE MOVEMENT

2020 ◽  
Vol 3 (2) ◽  
pp. 337-343
Author(s):  
Muliyani Muliyani ◽  
◽  
Nazhipah Isnani ◽  
Enny Fauziah
Keyword(s):  
Rheumatoid Arthritis ◽  
Pharmacological Treatment ◽  
Zingiber Officinale ◽  
Active Movement ◽  
Natural Medicine ◽  
Liver And Kidney ◽  
History Of ◽  
Inflammatory Drugs ◽  
Anti Inflammatory ◽  
Pre Treatment

Rheumatoid arthritis (RA) is the most common autoimmune inflammatory arthritis in adults. Pharmacological treatment is quite effective to overcome it, but in some cases, especially in elderly RA sufferers, pharmacological treatment such as non-steroidal anti-inflammatory drugs (NSAIDs), corticosteroids and DMARD (Disease Modifying Antirheumatic Drugs) have an impact on drug side effects, namely gastrointestinal disorders that cause toxic effects on liver and kidney. The developed natural medicine treatment has been supported by several previous studies that provide anti-inflammatory benefits, namely, ginger (Zingiber Officinale Rosc.). Ginger (Zingiber Officinale Rosc.) The method used is descriptive. The purpose of this study was to determine the characteristics of respondents who suffer from rheumathoid arthritic therapy with essential ginger oil and resisted active movement. The results of the study showed that as many as 20 respondents who suffered from rheumatoid arthritis, based on their characteristics, the most were female, namely 16 people (80%, ages 60-75 years, as many as 15 people (75%), the most part of the joints experiencing rheumathoid arthritis. occurred in the knee as many as 9 people (45%), work history, at most not working as many as 8 people (40%), history of injury, there were most injuries as many as 12 people (60%)

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