“Effect of a Discordant Opinion offered by a Second Opinion Physician on the Patient’s Decision for Management of Spinal Disc Disease”

Current Alternatives for Treatment of Degenerative Spinal Disc Disease

Journal of Spine & Neurosurgery ◽

10.4172/2325-9701.1000e104 ◽

2012 ◽

Vol 01 (02) ◽

Author(s):

A. Fahir Ozer

Keyword(s):

Disc Disease ◽

Spinal Disc

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INFLUENCE OF PHYSIOTHERAPY AND BALNEOTHERAPY IN PATIENTS WITH SPINAL DISC DISEASE

Journal of Applied Sports Sciences ◽

10.37393/jass.2018.02.7 ◽

2018 ◽

Vol 2 (December) ◽

pp. 73-80

Author(s):

Antoaneta Dimitrova ◽

◽

Kristin Grigorova-Petrova ◽

Daniela Lubenova ◽

Milena Nikolova ◽

...

Keyword(s):

Disc Disease ◽

Spinal Disc

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Prevalence of Spinal Disc Disease Among Interventional Cardiologists

The American Journal of Cardiology ◽

10.1016/s0002-9149(96)00678-9 ◽

1997 ◽

Vol 79 (1) ◽

pp. 68-70 ◽

Cited By ~ 111

Author(s):

Allan M. Ross ◽

Jerome Segal ◽

David Borenstein ◽

Ellen Jenkins ◽

Shuyan Cho

Keyword(s):

Disc Disease ◽

Spinal Disc

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An Intelligent Bone Spinal Disc Implant for Asian Population

Journal of Medical Devices ◽

10.1115/1.3134841 ◽

2009 ◽

Vol 3 (2) ◽

Author(s):

C. Chui ◽

M. N. Jonaidi ◽

S. Kuang

Keyword(s):

Computer Simulation ◽

Vertebral Body ◽

Pressure Sensors ◽

Asian Population ◽

Control Mechanisms ◽

Disc Disease ◽

Fibre Optics ◽

Motion Preservation ◽

Spinal Disc ◽

Prototype Device

There is a high level of patient appeal and physician acceptance of motion preservation as the future treatment of symptomatic and painful degenerative disc disease. However, spinal artificial disc replacement is still in its infancy. We have been designing, developing and evaluating motor articulated implants for use in bone-spinal disc surgery for Asian population. Apart from the generally smaller built of Asian compared to the American and European, the motor articulated implant should make provisions for the difference in eastern and western lifestyles. In the eastern world, we generally sit on a lower platform. Frequent activities like squatting result in a different stress-strain profile on the lower spine of an Asian compared to that of the Westerner. Preserving the motion of flexion bending in human lumbar spine is important. The motion preservation characteristics have to be maintained without compromising device durability, bone-device interfaces and corrective intervention. A systematic approach was adapted in designing the implant. Physical size of the implant should replicate the actual Intravertebral Disc (IVD). Implant should be able to fit into vertebral body. This is aid by shaping the spine vertebral body to accommodate the implant. A motor articulated implant must have suitable spaces for the implementation of sensors to detect forces and motors to control the motion of the prototype. The device must be able to receive real-time sensory inputs which can then modulate the implant orientation in bending accordingly. A prototype of the implant device has been fabricated to study its motion preservation capabilities. The prototype comprises of a parallel manipulator mechanism where the top plate is linked to the base plate by independent kinematic chains. The mechanical structure is made of Aluminium 6061. The mechanical parts were also put through the chemical process of anodizing for a good finishing surface. In the prototype device, we used three DC micromotors (Faulhaber) for actuation. Due to the small dimension, fibre optics pressure sensors were used. Three customized sensors were developed, calibrated and deployed on the upper plate. A PIC32 microprocessor was used to compute the compliance motion of the prototype when subjected to forces during flexion bending motion. The computer simulation of the kinematics of the parallel mechanism demonstrated the implant's flexion bending capabilities. We are conducting biomechanical experiments with this prototype implant deployed between L3–L5 of an artificial spinal column. The prototype device should achieve motion preservation capabilities comparable to the existing implants. More computer simulation will also be conducted to improve the mechanical design and control mechanisms of the proposed disc implant.

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901-15 Interventional Cardiologists Suffer an Excessive Incidence of Spinal Disc Disease

Journal of the American College of Cardiology ◽

10.1016/0735-1097(95)91492-g ◽

1995 ◽

Vol 25 (2) ◽

pp. 8A

Author(s):

Allan M. Ross ◽

David Borenstein ◽

Ellen Jenkins ◽

Shyuan Cho ◽

Jerome Segal

Keyword(s):

Disc Disease ◽

Spinal Disc

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Degenerative spinal disc disease and its treatment

Orthopaedics and Trauma ◽

10.1016/j.mporth.2017.09.009 ◽

2017 ◽

Vol 31 (6) ◽

pp. 378-387 ◽

Cited By ~ 1

Author(s):

Alexander Rossdeutsch ◽

Phillip Copley ◽

Sadaquate Khan

Keyword(s):

Disc Disease ◽

Spinal Disc

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Does Needle Design Affect the Regenerative Potential of Bone Marrow Aspirate? An In Vitro Study

Life ◽

10.3390/life11080748 ◽

2021 ◽

Vol 11 (8) ◽

pp. 748

Author(s):

Nadia Feddahi ◽

Monika Herten ◽

Tjark Tassemeier ◽

Heike Rekasi ◽

Alexander Hackel ◽

...

Keyword(s):

Bone Marrow ◽

Iliac Crest ◽

Mononuclear Cells ◽

Bone Marrow Aspirate ◽

In Vitro Study ◽

Contralateral Side ◽

Disc Disease ◽

Significant Difference ◽

Spinal Disc

While autologous bone is still the gold standard for treatment of bone defects, its availability is limited. Sufficient numbers of mesenchymal stroma cells (MSC) may be an alternative. Small volumes of bone marrow aspirate (BMA) were harvested with two different needle systems comparing the yield and regenerative potency of the MSCs. BMA (10 mL) was aspirated from the posterior iliac crest of 12 patients with degenerative spinal disc disease using both needle systems in each patient: the Jamshidi needle (JAM) and on the contralateral side the Marrow Cellution® Needle (AMC). Number of mononuclear cells (MNCs) and regeneration capacity (colony-forming unit/CFU) were determined. MSCs were characterized for surface markers and their differentiation into trilineages. There was no significant difference between the two harvesting needles regarding the quantity of MNCs in BMA: 5.2 ± 1.8 × 109 MNC/mL for AMC vs. 4.8 ± 2.5 × 109 MNC/mL for JAM, p = 0.182. The quantity of CFUs per ml BMA was similar for both groups: 3717 ± 5556 for AMC and 4305 ± 5507 for JAM (p = 0.695). The potency of MSCs expressed as colony-forming potential per 106 MNC resulted in 0.98 ± 1.51 for AMC and 1.00 ± 0.96 for JAM (p = 0.666). Regardless of the needle design, 10 mL bone marrow aspirate contains a sufficient number of about 40,000 MSCs that can be used to enhance bone healing.

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Case Example: Adjacent Segment Disease: What Is It, and How Is It Rated?

Guides Newsletter ◽

10.1001/amaguidesnewsletters.2011.marapr02 ◽

2011 ◽

Vol 16 (2) ◽

pp. 8-9

Author(s):

Marjorie Eskay-Auerbach

Keyword(s):

Clinical Symptoms ◽

Lumbar Fusion ◽

Adjacent Segment Degeneration ◽

Adjacent Segment Disease ◽

Adjacent Segment ◽

Disc Space Narrowing ◽

Disc Disease ◽

Disc Space ◽

Radiographic Findings ◽

Asymptomatic Patients

Abstract The incidence of cervical and lumbar fusion surgery has increased in the past twenty years, and during follow-up some of these patients develop changes at the adjacent segment. Recognizing that adjacent segment degeneration and disease may occur in the future does not alter the rating for a cervical or lumbar fusion at the time the patient's condition is determined to be at maximum medical improvement (MMI). The term adjacent segment degeneration refers to the presence of radiographic findings of degenerative disc disease, including disc space narrowing, instability, and so on at the motion segment above or below a cervical or lumbar fusion. Adjacent segment disease refers to the development of new clinical symptoms that correspond to these changes on imaging. The biomechanics of adjacent segment degeneration have been studied, and, although the exact mechanism is uncertain, genetics may play a role. Findings associated with adjacent segment degeneration include degeneration of the facet joints with hypertrophy and thickening of the ligamentum flavum, disc space collapse, and translation—but the clinical significance of these radiographic degenerative changes remains unclear, particularly in light of the known presence of abnormal findings in asymptomatic patients. Evaluators should not rate an individual in anticipation of the development of changes at the level above a fusion, although such a development is a recognized possibility.

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