scholarly journals Accumulated exposure to unemployment is related to impaired glucose metabolism in middle-aged men: A follow-up of the Northern Finland Birth Cohort 1966

2017 ◽  
Vol 11 (4) ◽  
pp. 365-372 ◽  
Author(s):  
Nina Rautio ◽  
Tuulia Varanka-Ruuska ◽  
Eeva Vaaramo ◽  
Saranya Palaniswamy ◽  
Rozenn Nedelec ◽  
...  
2020 ◽  
Vol 77 (5) ◽  
pp. 324-332 ◽  
Author(s):  
Tuulia Varanka-Ruuska ◽  
Mimmi Tolvanen ◽  
Eeva Vaaramo ◽  
Sirkka Keinänen-Kiukaanniemi ◽  
Sylvain Sebert ◽  
...  

ObjectiveTo evaluate how clinically measured glucose metabolism categories predict registered participation in working life.MethodsIn the 46-year follow-up of Northern Finland Birth Cohort 1966 (n=5328, 2342 men and 2986 women), we used oral glucose tolerance tests, surveys and glycated haemoglobin to determine glucose metabolism categorised as normal, pre-diabetes, screen-detected and previous type 2 diabetes (T2D). Consequent participation in working life during the 2-year follow-up period was measured as registered disability, unemployment and employment days, for which incidence rate ratios (IRRs) with 95% CIs were calculated using Poisson regression, adjusted for baseline employment and socioeconomic, health-related and behavioural factors.ResultsIn comparison to normal glucose, all categories of impaired glucose metabolism were associated with poorer participation in working life in the unadjusted models. After adjustments, the risks (IRR (95% CI)) of disability days remained heightened by both screen-detected and previous T2D among men (1.3 (1.3 to 1.4) and 1.5 (1.4 to 1.5), respectively), whereas among women the risks were lowered (0.9 (0.8 to 0.9) and 0.9 (0.9 to 1.0), respectively). The risks of unemployment were consistently higher in all categories of impaired glucose metabolism, and were the highest among women with previous T2D (1.6 (1.5 to 1.6)). Correspondingly, the rates of total employment days were lower in relation to screen-detected T2D among men and women (5% and 6%, respectively), and previous T2D (6% and 3%).ConclusionsOverall, impaired glucose metabolism associated with deteriorated working life participation already in middle age. The high prevalence of impaired glucose metabolism emphasises the need for actions to support sustainable working careers.


PLoS ONE ◽  
2019 ◽  
Vol 14 (1) ◽  
pp. e0211070 ◽  
Author(s):  
Jessica Ares ◽  
Sergio Valdés ◽  
Patricia Botas ◽  
Cecilia Sánchez-Ragnarsson ◽  
Sandra Rodríguez-Rodero ◽  
...  

PLoS ONE ◽  
2017 ◽  
Vol 12 (10) ◽  
pp. e0184808 ◽  
Author(s):  
M. Gholampour Dehaki ◽  
A. Amouzegar ◽  
H. Delshad ◽  
Y. Mehrabi ◽  
M. Tohidi ◽  
...  

Endocrine ◽  
2011 ◽  
Vol 40 (2) ◽  
pp. 265-272 ◽  
Author(s):  
Yu Xu ◽  
Min Xu ◽  
Yun Huang ◽  
Tiange Wang ◽  
Mian Li ◽  
...  

PLoS ONE ◽  
2019 ◽  
Vol 14 (5) ◽  
pp. e0216629
Author(s):  
Jessica Ares ◽  
Sergio Valdés ◽  
Patricia Botas ◽  
Cecilia Sánchez-Ragnarsson ◽  
Sandra Rodríguez-Rodero ◽  
...  

PLoS ONE ◽  
2017 ◽  
Vol 12 (10) ◽  
pp. e0185371 ◽  
Author(s):  
Maria Elena Lunati ◽  
Maria Francesca Bedeschi ◽  
Veronica Resi ◽  
Valeria Grancini ◽  
Eva Palmieri ◽  
...  

2022 ◽  
Vol 10 (1) ◽  
pp. 10
Author(s):  
Oelisoa M. Andriankaja ◽  
Kaumudi Joshipura ◽  
Francisco Muñoz ◽  
Bruce A. Dye ◽  
Frank B. Hu ◽  
...  

We evaluated the relationship between glucose abnormalities and periodontitis in overweight/obese individuals. Eight hundred and seventy (870) diabetes-free participants aged 40–65 years completed the three-year follow-up in the San Juan Overweight Adults Longitudinal Study. The ADA thresholds for fasting and 2-h post-load glucose and HbA1c were used to define prediabetes. The NHANES methods were used to assess periodontitis. Multivariable linear regression was used to evaluate the relationship between baseline glucose metabolism measures and periodontitis at follow-up, adjusting for potential confounders. There was no association between impaired glucose measures and mean pocket depth (PD), mean clinical attachment loss (CAL), or mean percent of sites ≥5 mm PD. Impaired glucose tolerance (IGT) was associated with a lower mean percent of sites ≥5 mm CAL (β = −1.6, p = 0.037). Prediabetes and impaired fasting glucose (IFG) were associated with improvement in mean percent of sites ≥5 mm PD (β = −1.4, p = 0.022; β = −1.6, p = 0.032; respectively). IFG and IGT were associated with improvement in mean percent of sites with ≥5 mm CAL (β = −1.6, p = 0.038; β = −1.9, p = 0.020; respectively). In conclusion, there were no consistent associations between baseline prediabetes or insulin resistance and periodontitis progression over a three-year period.


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