Comparison of efficacy and safety of once- versus twice-daily insulin detemir added on to oral antidiabetics in insulin-naive type 2 diabetes patients: 24-week, crossover, treat to target trial in a single center

Soner Cander; Oguzhan Sitki Dizdar; Ozen Oz Gul; Metin Guclu; Oguz Kaan Unal; Ercan Tuncel; Erdinc Erturk; Sazi Imamoglu; Canan Ersoy

doi:10.1016/j.pcd.2014.01.010

Comparison of efficacy and safety of once- versus twice-daily insulin detemir added on to oral antidiabetics in insulin-naive type 2 diabetes patients: 24-week, crossover, treat to target trial in a single center

Primary Care Diabetes ◽

10.1016/j.pcd.2014.01.010 ◽

2014 ◽

Vol 8 (3) ◽

pp. 256-264 ◽

Cited By ~ 2

Author(s):

Soner Cander ◽

Oguzhan Sitki Dizdar ◽

Ozen Oz Gul ◽

Metin Guclu ◽

Oguz Kaan Unal ◽

...

Keyword(s):

Type 2 Diabetes ◽

Insulin Detemir ◽

Treat To Target ◽

Efficacy And Safety ◽

Oral Antidiabetics ◽

Single Center ◽

Target Trial ◽

Daily Insulin ◽

Diabetes Patients

Download Full-text

Efficacy and safety of once‐daily insulin degludec dosed flexibly at convenient times vs fixed dosing at the same time each day in a Japanese cohort with type 2 diabetes: A randomized, 26‐week, treat‐to‐target trial

Journal of Diabetes Investigation ◽

10.1111/jdi.12502 ◽

2016 ◽

Vol 7 (5) ◽

pp. 711-717 ◽

Cited By ~ 9

Author(s):

Takashi Kadowaki ◽

Hideaki Jinnouchi ◽

Kohei Kaku ◽

Malene L Hersløv ◽

Jacob Hyllested‐Winge ◽

...

Keyword(s):

Type 2 Diabetes ◽

Insulin Degludec ◽

Treat To Target ◽

Efficacy And Safety ◽

Target Trial ◽

Once Daily ◽

Daily Insulin ◽

Japanese Cohort

Download Full-text

A 24-Week, Randomized, Treat-to-Target Trial Comparing Initiation of Insulin Glargine Once-Daily With Insulin Detemir Twice-Daily in Patients With Type 2 Diabetes Inadequately Controlled on Oral Glucose-Lowering Drugs

Diabetes Care ◽

10.2337/dc09-2294 ◽

2010 ◽

Vol 33 (6) ◽

pp. 1176-1178 ◽

Cited By ~ 101

Author(s):

S. G. Swinnen ◽

M.-P. Dain ◽

R. Aronson ◽

M. Davies ◽

H. C. Gerstein ◽

...

Keyword(s):

Type 2 Diabetes ◽

Insulin Glargine ◽

Insulin Detemir ◽

Treat To Target ◽

Oral Glucose ◽

Target Trial ◽

Once Daily ◽

Glucose Lowering

Download Full-text

Once-Weekly Exenatide Versus Once- or Twice-Daily Insulin Detemir: Randomized, open-label, clinical trial of efficacy and safety in patients with type 2 diabetes treated with metformin alone or in combination with sulfonylureas

Diabetes Care ◽

10.2337/dc12-1333 ◽

2012 ◽

Vol 36 (5) ◽

pp. 1368-1376 ◽

Cited By ~ 46

Author(s):

M. Davies ◽

S. Heller ◽

S. Sreenan ◽

H. Sapin ◽

O. Adetunji ◽

...

Keyword(s):

Type 2 Diabetes ◽

Clinical Trial ◽

Insulin Detemir ◽

Efficacy And Safety ◽

Open Label ◽

Daily Insulin

Download Full-text

Efficacy and safety of a fixed-ratio combination of insulin degludec and liraglutide (IDegLira) compared with its components given alone: results of a phase 3, open-label, randomised, 26-week, treat-to-target trial in insulin-naive patients with type 2 diabetes

The Lancet Diabetes & Endocrinology ◽

10.1016/s2213-8587(14)70174-3 ◽

2014 ◽

Vol 2 (11) ◽

pp. 885-893 ◽

Cited By ~ 185

Author(s):

Stephen C L Gough ◽

Bruce Bode ◽

Vincent Woo ◽

Helena W Rodbard ◽

Sultan Linjawi ◽

...

Keyword(s):

Type 2 Diabetes ◽

Fixed Ratio ◽

Insulin Degludec ◽

Treat To Target ◽

Efficacy And Safety ◽

Target Trial ◽

Open Label ◽

Phase 3

Download Full-text

The Efficacy and Safety of Insulin Degludec Given in Variable Once-Daily Dosing Intervals Compared With Insulin Glargine and Insulin Degludec Dosed at the Same Time Daily: A 26-week, randomized, open-label, parallel-group, treat-to-target trial in individuals with type 2 diabetes

Diabetes Care ◽

10.2337/dc12-1668 ◽

2013 ◽

Vol 36 (4) ◽

pp. 858-864 ◽

Cited By ~ 148

Author(s):

L. Meneghini ◽

S. L. Atkin ◽

S. C. L. Gough ◽

I. Raz ◽

L. Blonde ◽

...

Keyword(s):

Type 2 Diabetes ◽

Insulin Degludec ◽

Treat To Target ◽

Efficacy And Safety ◽

Target Trial ◽

Open Label ◽

Once Daily ◽

Parallel Group ◽

Dosing Intervals

Download Full-text

A 26-Week, Randomized, Parallel, Treat-to-Target Trial Comparing Insulin Detemir With NPH Insulin as Add-On Therapy to Oral Glucose-Lowering Drugs in Insulin-Naive People With Type 2 Diabetes

Diabetes Care ◽

10.2337/dc05-1365 ◽

2006 ◽

Vol 29 (6) ◽

pp. 1269-1274 ◽

Cited By ~ 452

Author(s):

K. Hermansen ◽

M. Davies ◽

T. Derezinski ◽

G. Martinez Ravn ◽

P. Clauson ◽

...

Keyword(s):

Type 2 Diabetes ◽

Insulin Detemir ◽

Treat To Target ◽

Oral Glucose ◽

Target Trial ◽

Nph Insulin ◽

Glucose Lowering

Download Full-text

Less weight gain and hypoglycaemia with once-daily insulin detemir than NPH insulin in intensification of insulin therapy in overweight Type 2 diabetes patients-The PREDICTIVE™ BMI clinical trial1

Diabetic Medicine ◽

10.1111/j.1464-5491.2008.02483.x ◽

2008 ◽

Vol 25 (8) ◽

pp. 916-923 ◽

Cited By ~ 49

Author(s):

C. Fajardo Montañana ◽

C. Hernández Herrero ◽

M. Rivas Fernández

Keyword(s):

Type 2 Diabetes ◽

Weight Gain ◽

Insulin Therapy ◽

Insulin Detemir ◽

Nph Insulin ◽

Once Daily ◽

Daily Insulin ◽

Diabetes Patients

Download Full-text

A randomised, 52-week, treat-to-target trial comparing insulin detemir with insulin glargine when administered as add-on to glucose-lowering drugs in insulin-naive people with type 2 diabetes

Diabetologia ◽

10.1007/s00125-007-0911-x ◽

2008 ◽

Vol 51 (3) ◽

pp. 408-416 ◽

Cited By ~ 305

Author(s):

J. Rosenstock ◽

M. Davies ◽

P. D. Home ◽

J. Larsen ◽

C. Koenen ◽

...

Keyword(s):

Type 2 Diabetes ◽

Insulin Glargine ◽

Insulin Detemir ◽

Treat To Target ◽

Target Trial ◽

Glucose Lowering

Download Full-text

A 26-Week, Randomized, Parallel, Treat-to-Target Trial Comparing Insulin Detemir With NPH Insulin as Add-On Therapy to Oral Glucose-Lowering Drugs in Insulin-Naïve People With Type 2 Diabetes

Yearbook of Endocrinology ◽

10.1016/s0084-3741(08)70010-6 ◽

2007 ◽

Vol 2007 ◽

pp. 12-14

Author(s):

L. Kennedy

Keyword(s):

Type 2 Diabetes ◽

Insulin Detemir ◽

Treat To Target ◽

Oral Glucose ◽

Target Trial ◽

Nph Insulin ◽

Glucose Lowering

Download Full-text

A randomized, treat-to-target trial comparing insulin lispro protamine suspension and insulin detemir in insulin-naive patients with Type 2 diabetes

Diabetic Medicine ◽

10.1111/j.1464-5491.2009.02899.x ◽

2010 ◽

Vol 27 (2) ◽

pp. 181-188 ◽

Cited By ~ 31

Author(s):

L. Fogelfeld ◽

M. Dharmalingam ◽

K. Robling ◽

C. Jones ◽

D. Swanson ◽

...

Keyword(s):

Type 2 Diabetes ◽

Insulin Lispro ◽

Insulin Detemir ◽

Treat To Target ◽

Target Trial

Download Full-text