The antinociceptive effect of stimulating the retrosplenial cortex in the rat tail-flick test but not in the formalin test involves the rostral anterior cingulate cortex

2015 ◽  
Vol 131 ◽  
pp. 112-118 ◽  
Author(s):  
Gláucia Melo Reis ◽  
Rafael Sobrano Fais ◽  
Wiliam A. Prado
Keyword(s):  
Anterior Cingulate Cortex ◽  
Formalin Test ◽  
Antinociceptive Effect ◽  
Cingulate Cortex ◽  
Retrosplenial Cortex ◽  
Anterior Cingulate ◽  
Tail Flick ◽  
Tail Flick Test ◽  
Rostral Anterior Cingulate Cortex ◽  
Rat Tail

scholarly journals Mental travel in the social domain

2019 ◽  
Author(s):  
Mordechai Hayman ◽  
Shahar Arzy
Keyword(s):  
Social Network ◽  
Anterior Cingulate Cortex ◽  
Brain Activity ◽  
Cingulate Cortex ◽  
Retrosplenial Cortex ◽  
Anterior Cingulate ◽  
Significant Other ◽  
Temporoparietal Junction ◽  
The Social ◽  
Famous Person

“Mental travel” is the ability to imagine oneself in different places and times and to adopt other people’s point of view (POV), also termed “Theory of Mind (ToM)”. While ToM has been extensively investigated, self-projection with respect to ones’ own and others’ social networks has yet to be systematically studied.Here we asked participants to “project” themselves to four different POVs: a significant other, a non-significant other, a famous-person, and their own-self. From each POV they were asked to rate the level of affiliation (closeness) to different individuals in the respective social network while undergoing functional MRI.Participants were always faster making judgments from their own POV compared to other POVs (self-projection effect) and for people who were personally closer to their adopted POV (self-reference effect). Brain activity at the medial prefrontal and anterior cingulate cortex in the self POV condition was found to be higher compared to all other conditions. Activity at the right temporoparietal junction and medial parietal cortex was found to distinguish between the personally related (self, significant- and non-significant others) and unrelated (famous-person) individuals within the social network. Regardless of the POV, the precuneus, anterior cingulate cortex, prefrontal cortex, and temporoparietal junction distinguished between relatively closer and distant people. Representational similarity analysis (RSA) implicated the left retrosplenial cortex as crucial for social distance processing across all POVs.

scholarly journals A connectional hub in the rostral anterior cingulate cortex links areas of emotion and cognitive control

eLife ◽  
2019 ◽  
Vol 8 ◽  
Author(s):  
Wei Tang ◽  
Saad Jbabdi ◽  
Ziyi Zhu ◽  
Michiel Cottaar ◽  
Giorgia Grisot ◽  
...  
Keyword(s):  
Anterior Cingulate Cortex ◽  
Diffusion Magnetic Resonance Imaging ◽  
Cingulate Cortex ◽  
Retrograde Tracing ◽  
Anterior Cingulate ◽  
Resonance Imaging ◽  
Macaque Monkeys ◽  
Afferent Inputs ◽  
Rostral Anterior Cingulate Cortex ◽  
A Site

We investigated afferent inputs from all areas in the frontal cortex (FC) to different subregions in the rostral anterior cingulate cortex (rACC). Using retrograde tracing in macaque monkeys, we quantified projection strength by counting retrogradely labeled cells in each FC area. The projection from different FC regions varied across injection sites in strength, following different spatial patterns. Importantly, a site at the rostral end of the cingulate sulcus stood out as having strong inputs from many areas in diverse FC regions. Moreover, it was at the integrative conjunction of three projection trends across sites. This site marks a connectional hub inside the rACC that integrates FC inputs across functional modalities. Tractography with monkey diffusion magnetic resonance imaging (dMRI) located a similar hub region comparable to the tracing result. Applying the same tractography method to human dMRI data, we demonstrated that a similar hub can be located in the human rACC.

scholarly journals Activations of muscarinic M1receptors in the anterior cingulate cortex contribute to the antinociceptive effect via GABAergic transmission

2017 ◽  
Vol 13 ◽  
pp. 174480691769233 ◽  
Author(s):  
Kohei Koga ◽  
Yu Matsuzaki ◽  
Kenji Honda ◽  
Fumihiro Eto ◽  
Tomonori Furukawa ◽  
...  
Keyword(s):  
Anterior Cingulate Cortex ◽  
Antinociceptive Effect ◽  
Cingulate Cortex ◽  
Anterior Cingulate ◽  
Gabaergic Transmission
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