Pharmacological and neurochemical evidence for antidepressant-like effects of the herbal product Catuama

2004 ◽  
Vol 78 (4) ◽  
pp. 757-764 ◽  
Author(s):  
Maria M. Campos ◽  
Elizabeth S. Fernandes ◽  
Juliano Ferreira ◽  
Léslei B. Bortolanza ◽  
Adair.R.S. Santos ◽  
...  
Keyword(s):  
Herbal Product

Diosgenin: Therapeutic Action, Pharmacology and Applications

2017 ◽  
Vol 5 (1) ◽  
pp. 7-15
Author(s):  
Sanasam Sanjeev ◽  
◽  
Maibam Sunita Devi ◽  
Khushboo Maurya ◽  
Vikas Kumar Roy ◽  
...  
Keyword(s):  
Hepatitis C ◽  
Drug Development ◽  
Liver Diseases ◽  
Potential Role ◽  
Wide Spectrum ◽  
Herbal Product ◽  
Biological Properties ◽  
Therapeutic Action ◽  
Pharmacokinetics And Pharmacodynamics ◽  
Beneficial Effects

Diosgenin [25R-spriost-5-en-3þ-ol], is an important steroidal metabolite found in various plant species. The discovery of diosgenin has made it one of the most researched and studied herbal product. Moreover, there is excellent opportunity to address whether diosgenin plays a role in chemoprevention versus therapy, or both. However, rigorous experimental based evidence in support of ethnomedicine-derived notions would lead to the development of products relevant to drug development. The health beneficial effects of diosgenin are further extended to its potential role to treat other ailments such as HIV and hepatitis-C infections as well as liver diseases. There is little information regarding the bioavailability, pharmacokinetics and pharmacodynamics of diosgenin in relation to its health beneficial effects. It has been reported to have wide spectrum of biological properties that contributes to several diseases in its role as a health beneficial phytochemical by citing new studies.

Effect of Ustukhuddus Alavi, a multi-herbal product, on the cognitive performance of adolescent female students

2022 ◽  
pp. 114971
Author(s):  
Samane Tefagh ◽  
Roshanak Mokaberinejad ◽  
Mehrdad Shakiba ◽  
Mahdi Jafari ◽  
Maryam Salehi ◽  
...  
Keyword(s):  
Cognitive Performance ◽  
Herbal Product ◽  
Female Students ◽  
Adolescent Female

scholarly journals The antecedents of herbal product actual purchase in Malaysia

2015 ◽  
pp. 771-780 ◽  
Author(s):  
Sarina Ismail ◽  
Sany Sanuri Mohd Mokhtar
Keyword(s):  
Herbal Product

scholarly journals A demographic analysis of consumers’ preference for green products

2019 ◽  
Author(s):  
Abdul Bashiru Jibril ◽  
Michael Adu Kwarteng ◽  
Miloslava Chovancova
Keyword(s):  
Sample Size ◽  
Practical Implication ◽  
Demographic Factors ◽  
Herbal Product ◽  
Nonparametric Test ◽  
Green Product ◽  
Green Products ◽  
Chi Square ◽  
Chi Square Test ◽  
Strength Of Association

Purpose – the aim of this research is to understand and present the outcomes of the strength of association between consumers and the use of the green (herbal) product from a demographic viewpoint. By extension, it measures the magnitude of dependents among demographic factors influencing the use of the green product in a developing country. Research methodology – to evaluate consumer’s demographics on the use of the green (herbal) product, 207 participants took part in the survey through a structured questionnaire. Data were obtained from users of green products (specifically herbs) in Ghana. A nonparametric test precisely chi-square test (x2) and Spearman's correlation rs were employed for our empirical analysis. Findings – the paper indicated the youthful population as the highest number of users of the green product in the herbal market. Results from the nonparametric test (Spearman’s rho) revealed that demographic factors (gender, age, education, and occupation) have an inverse relationship on the use of the green product. Whiles the chi-square test also discloses insignificant relationships among the observed attributes. This suggests that there is no empirical evidence to support the claim that use of green product depends on demographic factors of consumers. Research limitations – the limitation of this study considered the research scope, taking into account a smaller sample size for the study hence, future researchers should expand the sample size as well the other demographic variables necessary for a similar study. Practical implications – the practical implication of this study gives insights to practitioners and marketers in the herbal industry on how best they can progress in their quest to sustain in the business. Originality/Value – the present study aided in widening the scope of consumer behaviour towards the green product in the marketing discipline taken into consideration the widespread competition in the business nowadays especially in the herbal (green product) market

scholarly journals Análisis microscópico y observaciones histoquímicas de la raíz medicinal de Iostephane heterophylla (Cav.) Benth. Ex Hemsl. (Asteraceae)

2017 ◽  
pp. 65
Author(s):  
Estela Sandoval ◽  
Robert A. Bye ◽  
Griselda Ríos ◽  
María Isabel Aguilar
Keyword(s):  
Medicinal Plants ◽  
Comparative Study ◽  
Herbal Product ◽  
Raw Material ◽  
Herbal Drug ◽  
Root Structure ◽  
Fast Green ◽  
Histological Techniques ◽  
Original Contribution ◽  
Phytochemical Studies

The roots of Iostephane heterophylla are popular in Mexican traditional medicine and as such are a good candidate to develop herbal drug preparations to be used as phytomedicine. International criteria for validation and standardization of a herbal product as phytomedicine include, among others, the integration of microscopic and histochemical characteristics of the raw material, as in this case the herbal drug, to guarantee its authenticity. As an original contribution to the knowledge of the root structure of this species, fresh roots fixed in FAA, were processed with conventional histological techniques (paraffin embedment and subsequent transversal and longitudinal sections that were stained with safranin-fast green) and stained with histochemical markers for identification of cellular contents. The root description includes dermic, fundamental and vascular tissues as well as cellular contents (proteins, polysaccharides, polyphenols, condensed and hydrolyzed tannins, starches and lipids, some of which have been isolated in previous phytochemical studies). These characteristics are compared to those of other species of Asteraceae as an initial comparative study to contribute to identify medicinal plants based upon their underground parts.

scholarly journals An Evaluation of the In Vitro Roles and Mechanisms of Silibinin in Reducing Pyrazinamide- and Isoniazid-Induced Hepatocellular Damage

2019 ◽  
Author(s):  
Zhang-He Goh ◽  
Jie Kai Tee ◽  
Han Kiat Ho
Keyword(s):  
Herbal Product ◽  
Complementary Therapy ◽  
Hepatoprotective Effect ◽  
Proof Of Concept ◽  
Drug Induced ◽  
Drug Induced Liver Injury ◽  
Nutraceutical Compounds ◽  
Hepatocellular Damage ◽  
Drug Regimens

AbstractTuberculosis remains a significant infectious lung disease that affects millions of patients worldwide. Despite numerous existing drug regimens for tuberculosis, Drug-Induced Liver Injury is a major challenge that limits the effectiveness of these therapeutics. Two drugs that form the backbone of the commonly administered quadruple antitubercular regimen, i.e. pyrazinamide (PZA) and isoniazid (INH), are associated with such hepatotoxicity. The problem is compounded by the lack of safe and effective alternatives to the antitubercular regimen. Consequently, current research largely focuses on exploiting the hepatoprotective effect of nutraceutical compounds as complementary therapy. Silibinin, a herbal product widely believed to protect against various liver diseases, potentially provides a useful solution given its hepatoprotective mechanisms. In our study, we identified silibinin’s role in mitigating PZA- and INH-induced hepatotoxicity and elucidated a deeper mechanistic understanding of silibinin’s hepatoprotective ability. 25 μM silibinin preserved the viability of human foetal hepatocyte line LO2 when co-administered with 80 mM INH and decreased apoptosis induced by a combination of 40 mM INH and 10 mM PZA by reducing oxidative damage to mitochondria, proteins, and lipids. Taken together, this proof-of-concept forms the rational basis for the further investigation of silibinin’s hepatoprotective effect in subsequent preclinical studies and clinical trials.Graphical Abstract

scholarly journals Acute Toxicity Study and Elemental Analysis of Gasca N Herbal Product

2019 ◽  
Vol 3 (6) ◽  
pp. 216-220
Author(s):  
Ibrahim Ismail ◽  
◽  
Kabir Nafisatu ◽  
Ibrahim Gezawa ◽  
Fakhraddeen Muhammad ◽  
...  
Keyword(s):  
Acute Toxicity ◽  
Elemental Analysis ◽  
Herbal Product ◽  
Toxicity Study ◽  
Acute Toxicity Study
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