50. Role of intraoperative cytology in the gamut of sellar-suprasellar lesions: Enigmas unearthed, lessons learnt

Pathology ◽  
2020 ◽  
Vol 52 ◽  
pp. S150
Author(s):  
B. Nayal ◽  
G. Vasudevan ◽  
P. Priya J ◽  
V. Monappa ◽  
R. Nair
Keyword(s):  
Lessons Learnt ◽  
Intraoperative Cytology

scholarly journals The Role of Intraoperative Cytology in the Diagnostic Evaluation of Ovarian Neoplasms

2012 ◽  
Vol 56 (5) ◽  
pp. 467-473 ◽  
Author(s):  
Mohammad Shahid ◽  
Sufian Zaheer ◽  
Aysha Mubeen ◽  
Khaliqur Rahman ◽  
Rana K. Sherwani
Keyword(s):  
Ovarian Neoplasms ◽  
Diagnostic Evaluation ◽  
Intraoperative Cytology

Role of frozen section associated with intraoperative cytology in comparison to FNA and FS alone in the management of thyroid nodules

2007 ◽  
Vol 33 (6) ◽  
pp. 769-775 ◽  
Author(s):  
F. Basolo ◽  
C. Ugolini ◽  
A. Proietti ◽  
P. Iacconi ◽  
P. Berti ◽  
...  
Keyword(s):  
Thyroid Nodules ◽  
Frozen Section ◽  
Intraoperative Cytology

scholarly journals The role of experts in postaccident recovery: lessons learnt from Chernobyl and Fukushima

2018 ◽  
Vol 47 (3-4) ◽  
pp. 254-259 ◽  
Author(s):  
J.C. Gariel ◽  
F. Rollinger ◽  
T. Schneider
Keyword(s):  
Recovery Process ◽  
Nuclear Accident ◽  
Public Authorities ◽  
Affected Area ◽  
Lessons Learnt ◽  
Informed Decisions

Following a nuclear accident, a major dilemma for affected people is whether to stay or leave the affected area, or, for those who have been evacuated, whether or not to return to the decontaminated zones. Populations who have to make such decisions have to consider many parameters, one of which is the radiological situation. Feedback from Chernobyl and Fukushima has demonstrated that involvement and empowerment of the affected population is a way to provide them with the necessary elements to make informed decisions and, if they decide to return to decontaminated areas, to minimise exposure by contributing to the development of a prudent attitude and vigilance towards exposure. However, involving stakeholders in postaccident management raises the question of the role of experts and public authorities in supporting the inhabitants who have to make decisions about their future. Based on experiences in Chernobyl and Fukushima, this paper will discuss various principles that have to be taken into account by experts and public authorities about their role and position when dealing with stakeholders in a postaccident recovery process.

scholarly journals Impacts and intricacies of mass quarantine on Covid-19 and possible role of artificial intelligence (AI) in mitigation

2020 ◽  
Author(s):  
Samara Bin Salem ◽  
Jagadeesan Premanandh
Keyword(s):  
Artificial Intelligence ◽  
Early Warning ◽  
Healthy Individuals ◽  
Lessons Learnt ◽  
Global Threat ◽  
The Impact

Ongoing Covid-19 is a new global threat with a devastating impact on lives and economy especially in China, the origination spot of epidemic. The catastrophic nature of an epidemic depends on isolation and quarantine measures. The impact of mass quarantine in China in containing Covid -19 has been discussed. Repercussions of mass quarantine and its profound adverse concerns on healthy individuals and economy has been presented. Role of artificial intelligence in early warning alert and its impacts are discussed. In conclusion, the ability to recognize outbreaks and act is still challenging as each event is unique in its own way. In other words, the causative organisms are smarter than human and human made algorithms. Nevertheless, the expensive lessons learnt enable us to prepare ourselves to prevent such disasters which is an on-going battle.

scholarly journals Evaluating intraoperative cytology with histopathology diagnosis and its importance in ovarian tumors

2020 ◽  
Vol 10 (1) ◽  
pp. 1630-1634
Author(s):  
Karishma Malla Vaidya ◽  
Bigya Shrestha ◽  
Runa Jha ◽  
Binit Shrestha ◽  
Aasiya Rajbhandari ◽  
...  
Keyword(s):  
Predictive Value ◽  
Ovarian Neoplasms ◽  
Ovarian Neoplasm ◽  
Imprint Cytology ◽  
Frozen Sections ◽  
Intraoperative Diagnosis ◽  
Touch Imprint Cytology ◽  
Intraoperative Cytology ◽  
Benign Ovarian Neoplasm

Background: Touch/ imprint cytology has been utilized for intraoperative evaluations of tumors to complement frozen sections in order to reach diagnosis prior to histopathology diagnosis. The main aim of this study is to find role of touch imprint in determining histopathology diagnosis of ovarian neoplasm. Materials and Methods: All together one hundred three cases were evaluated using both touch/imprint and histopathology diagnosis. The histopathology diagnoses consisted of Benign (n=85), borderline (n=4), and malignant (n=12). Touch imprint cytology consists of Negative for malignancy (n=90), Positive for malignancy (n=11) and inadequate (n=2). Inadequate smear was excluded from the study. Results: Both touch / imprint cytology were able to diagnose benign and malignant ovarian neoplasm. Out of 103 cases, in cytology showed 89.1% patients were negative and 10.9% patients were positive. Histopathology shows 84.2% of benign ovarian neoplasm, 3.9% borderline neoplasm and 11.9% of malignant. Diagnostic accuracy of touch/ imprint was 99% with sensitivity 100% and specificity was 91.67%. Positive predictive value was 98.89% and negative predictive value was 100%. Conclusion: Touch/ imprint cytology examination is simple, rapid and useful test in evaluation of ovarian neoplasms. It plays very important role in preliminary intraoperative diagnosis of benign and malignant ovarian neoplasms. 

The Role of Economic Community for West African States (ECOWAS) in Post-Conflict Rehabilitation: Lessons from Liberia

2017 ◽  
Author(s):  
Chris Kwaja
Keyword(s):  
Content Analysis ◽  
Rehabilitation Program ◽  
West African ◽  
Violent Conflict ◽  
Economic Community ◽  
Center Stage ◽  
Post Conflict ◽  
Lessons Learnt ◽  
Violent Conflicts

In the aftermath of the violent conflict in Liberia, the issue of post- conflict rehabilitation took center stage, with the Economic Community of West African States (ECOWAS) deeply involved in an elaborate post-conflict rehabilitation program in the country. Through the use of content analysis, this paper explores the involvement of ECOWAS in post-conflict rehabilitation in Liberia in the context of the devastating consequences of violent conflicts that the country experienced. In specific terms, it highlights key lessons learnt from the ECOWAS intervention in Liberia, as part of its mandate for peace, security and stability in the region.

P–222 Can we optimise the time that we perform the fertilisation check in the lab? Lessons learnt from time-lapse incubation

2021 ◽  
Vol 36 (Supplement_1) ◽  
Author(s):  
A Barrie ◽  
R Smith ◽  
L Best ◽  
N Davis ◽  
S Duffy ◽  
...  
Keyword(s):  
Study Design ◽  
Fetal Heart ◽  
Time Lapse ◽  
Trial Registration ◽  
Optimum Time ◽  
Use Of Time ◽  
Lessons Learnt ◽  
Registration Number

Abstract Study question Can time-lapse data be used to identify the optimum time to perform the fertilisation check for oocytes cultured in standard incubation? Summary answer The optimum time to perform fertilisation checks for oocytes cultured in standard incubation is 16.5hpi+/–0.5h. What is known already Time-lapse incubation allows the embryologist to retrospectively review collated images of oocytes and embryos to capture important embryological observations that may have otherwise been missed. This is a luxury not available to embryologists when oocytes or embryos are cultured in standard incubation. Traditionally, the optimum time to perform the fertilisation check is 17 hours post insemination (hpi) +/- 1 hour. It was hypothesised that this could be fine-tuned ensuring the maximum number of fertilised oocytes were observed, thereby increasing the number of usable embryos for the patient. Study design, size, duration This was a retrospective, multicentre analysis including data from 27,022 ICSI derived embryos cultured in time-lapse incubation between January 2011 to November 2019. Participants/materials, setting, methods The time of pronuclei appearance and disappearance was recorded using the time-lapse incubation software. The number of oocytes exhibiting normal fertilisation (defined as the presence of two pronuclei) during 30 minute intervals from 15hpi to 20hpi was determined. Main results and the role of chance Between 15–17.5hpi the average number of oocytes exhibiting normal fertilisation was 98.19% with most oocytes having visible pronuclei at 16–16.5hpi (98.32%). At 18–18.5hpi the number of visible pronuclei falls to 95.53% and continues to fall to 87.02% at 19.5–20hpi meaning that over 3000 (11%) normally fertilised oocytes, within this cohort, would not be identified. Limitations, reasons for caution The conclusions of this investigation cannot be effectively extrapolated to IVF embryos as only ICSI embryos were used for the determination of the results. Wider implications of the findings: The optimum time to perform fertilisation checks for oocytes cultured in standard incubation is 16.5hpi+/–0.5h. However, without the use of time-lapse incubation, the fertilisation of at least 2% of embryos that create a fetal heart will be missed, even if the fertilisation check is performed in the optimum window (16.5hpi+/–0.5h). Trial registration number Not applicable

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