Acantholytic squamous cell carcinoma of the oesophagus with prevalent single isolated tumour cells including signet ring cells and many osteoclast-like giant cells

Pathology ◽  
2016 ◽  
Vol 48 (3) ◽  
pp. 281-283 ◽  
Author(s):  
Dakeun Lee
Keyword(s):  
Squamous Cell Carcinoma ◽  
Cell Carcinoma ◽  
Squamous Cell ◽  
Giant Cells ◽  
Tumour Cells ◽  
Signet Ring Cells ◽  
Signet Ring ◽  
Isolated Tumour Cells ◽  
Acantholytic Squamous Cell Carcinoma

Prognostic significance of VEGF-C in predicting micrometastasis and isolated tumour cells in N0 oral squamous cell carcinoma

2016 ◽  
Vol 46 (3) ◽  
pp. 194-200 ◽  
Author(s):  
Sarvambika Kazakydasan ◽  
Zainal Ariff Abdul Rahman ◽  
Siti Mazlipah Ismail ◽  
Mannil Thomas Abraham ◽  
Thomas George Kallarakkal
Keyword(s):  
Squamous Cell Carcinoma ◽  
Oral Squamous Cell Carcinoma ◽  
Cell Carcinoma ◽  
Squamous Cell ◽  
Prognostic Significance ◽  
Tumour Cells ◽  
Isolated Tumour Cells

Immature glandular features in squamous cell carcinoma of the uterine cervix as an independent indicator of resistance to radiotherapy

2002 ◽  
Vol 12 (3) ◽  
pp. 277-285
Author(s):  
S Okada ◽  
H Tsuda ◽  
K Ohmi ◽  
T Kasamatsu ◽  
T Yamada ◽  
...  
Keyword(s):  
Squamous Cell Carcinoma ◽  
Cell Carcinoma ◽  
Squamous Cell ◽  
Uterine Cervix ◽  
Squamous Differentiation ◽  
Signet Ring Cells ◽  
Nuclear Atypia ◽  
Signet Ring ◽  
Patient Prognosis ◽  
Independent Indicator

Abstract.Okada S, Tsuda H, Ohmi K, Kasamatsu T, Yamada T, Tsunematsu R, Sumi M, Tokuuye K, Yoshikawa H, Hirohashi S. Immature glandular features in squamous cell carcinoma of the uterine cervix as an independent indicator of resistance to radiotherapy.The aim of this study was to evaluate the significance of “immature glandular features” in cervical squamous cell carcinoma (SCC) as an indicator of tumor radioresistance. Pretreatment biopsied tissue specimens of cervical SCC from 100 patients who were uniformly treated with radiotherapy alone were classified into clinically radioresistant (cR) and radiosensitive (cS) groups. Seven histologic parameters comprising glassy cells, signet ring cells, squamous differentiation, recognizable gland, nuclear atypia, stromal response, and mitotic counts were examined. Glassy cells and signet ring cells were regarded as “immature glandular features”. The correlation of these seven parameters with tumor response to radiotherapy and patient prognosis was analyzed by univariate and multivariate analyses. As objective indicators of glandular differentiation, alcian-blue staining and immunostaining of cytokeratins 7 and 20 were also performed. It was revealed that immature glandular features, absence of squamous differentiation, and low nuclear atypia were significant indicators of radioresistance of the tumor and of poorer patient prognosis. Combining those histological parameters, the present SCC cases were classified into 26 pathologically radioresistant (pR) and 74 radiosensitive (pS) groups. In the pR group, 54% (14 of 26) were clinically radioresistant, whereas 20% (15 of 74) of the pS group were clinically radioresistant (P = 0.002). The overall prognosis of the pR group was much poorer than that of the pS group (P < 0.0001). This correlation also held true in cases of identical stage and age. We could not show objectively glandular differentiation of “immature glandular features”. Nonetheless, the identification of “immature glandular features” was effective in predicting the radiotherapy resistance of cervical SCC and poorer patient prognosis.

scholarly journals Incidence of Micrometastasis and Isolated Tumour Cells in Clinicopathologically Node-Negative Head and Neck Squamous Cell Carcinoma

2019 ◽  
Vol 19 (1) ◽  
pp. 131-135 ◽  
Author(s):  
Kinjal Shankar Majumdar ◽  
Vishal U. S. Rao ◽  
Rachana Prasad ◽  
Veena Ramaswamy ◽  
Piyush Sinha ◽  
...  
Keyword(s):  
Squamous Cell Carcinoma ◽  
Cell Carcinoma ◽  
Head And Neck ◽  
Squamous Cell ◽  
Tumour Cells ◽  
Neck Squamous Cell Carcinoma ◽  
Node Negative ◽  
Isolated Tumour Cells

Intra-oral Acantholytic Squamous Cell Carcinoma: 55 Cases. Is this Variant more Aggressive?

2021 ◽  
Author(s):  
Michael Abba ◽  
Ilana Kaplan ◽  
Alejandro Livoff ◽  
Amram Zagury ◽  
Oded Nahlieli ◽  
...  
Keyword(s):  
Squamous Cell Carcinoma ◽  
Cell Carcinoma ◽  
Squamous Cell ◽  
Acantholytic Squamous Cell Carcinoma

Acantholytic squamous cell carcinoma of the maxillary gingiva: Case report and literature review

2014 ◽  
Vol 26 (4) ◽  
pp. 488-491 ◽  
Author(s):  
Shigeo Ishikawa ◽  
Hitoshi Ishikawa ◽  
Tomoya Kato ◽  
Hirohiko Tachibana ◽  
Takehito Kobayashi ◽  
...  
Keyword(s):  
Squamous Cell Carcinoma ◽  
Case Report ◽  
Literature Review ◽  
Cell Carcinoma ◽  
Squamous Cell ◽  
Acantholytic Squamous Cell Carcinoma
Sign in / Sign up

Export Citation Format

Share Document