Pancreatic Quantitative Sensory Testing in Painful Chronic Pancreatitis Can Predict Pain Response After Intervention: a Pilot Study

Pancreatology ◽  
2020 ◽  
Vol 20 ◽  
pp. S90
Author(s):  
M. Faghih ◽  
A. Philips ◽  
A. Drewes ◽  
E. Afghani ◽  
V. Singh ◽  
...  
Keyword(s):  
Chronic Pancreatitis ◽  
Pilot Study ◽  
Quantitative Sensory Testing ◽  
Pain Response ◽  
Sensory Testing

Quantitative Sensory Testing in Animal Models of Chronic Pain: A Pilot Study

2018 ◽  
Author(s):  
B. Monteiro ◽  
M. Moreau ◽  
C. Otis ◽  
L. De Lorimier ◽  
J. Pelletier ◽  
...  
Keyword(s):  
Chronic Pain ◽  
Pilot Study ◽  
Animal Models ◽  
Quantitative Sensory Testing ◽  
Sensory Testing

scholarly journals A pilot study investigating whether quantitative sensory testing alters after treatment in patients with fibromyalgia

2018 ◽  
Vol 12 (4) ◽  
pp. 250-256 ◽  
Author(s):  
Theresa Wodehouse ◽  
Kavita Poply ◽  
Shankar Ramaswamy ◽  
Saowarat Snidvongs ◽  
Julius Bourke ◽  
...  
Keyword(s):  
Pilot Study ◽  
Quantitative Sensory Testing ◽  
Fibromyalgia Impact Questionnaire ◽  
Pain Modulation ◽  
Conditioned Pain Modulation ◽  
Sensory Testing ◽  
Central Sensitisation ◽  
Pain Thresholds ◽  
Pressure Pain ◽  
Pressure Pain Thresholds

Background: Fibromyalgia is a chronic musculoskeletal pain condition that is often associated with sleep disturbances and fatigue. The pathophysiology of fibromyalgia is not understood, but indirect evidence suggests a central dysfunction of the nociceptive modulating system. The aim of this study was to evaluate whether quantitative sensory testing detects a change in pain thresholds in fibromyalgia patient receiving pregabalin treatment. Methods: A total of 25 patients were recruited for the study and received routine pregabalin, but only 14 patients completed the treatment. Assessment of pressure pain thresholds and changes in conditioned pain modulation using ischaemic pain as a conditioning stimulus were measured at baseline and every 4 weeks for 12 weeks. Fibromyalgia impact questionnaire, PainDETECT and SF-12 were also completed. Results: Patients with fibromyalgia demonstrated a less-efficient conditioned pain modulation at baseline. An efficient conditioned pain modulation was observed at 1 month and this was maintained until the final visit. Pressure pain thresholds (PPTs) showed a significant improvement from baseline. Patients also reported a similar magnitude of improvements in PainDETECT, fibromyalgia impact questionnaire (FIQ) and its impact on daily life and change in outcome for SF-12. Conclusion: This pilot study reports an increase in PPTs and improved conditioned pain modulation response after commencing pregabalin, which was maintained at 12 weeks, and this was supported by positive pain scores. Pregabalin is a licenced treatment for fibromyalgia in Europe, and its response to central sensitisation, particularly ‘dynamic responses’, has not been reported. We conclude that pregabalin has the potential to reduce peripheral and central sensitisation in patients with fibromyalgia, as measured using quantitative sensory testing.

Reliability of Static and Dynamic Quantitative Sensory Testing in Patients With Painful Chronic Pancreatitis

2012 ◽  
Vol 37 (5) ◽  
pp. 530-536 ◽  
Author(s):  
Søren S. Olesen ◽  
Harry van Goor ◽  
Stefan A.W. Bouwense ◽  
Oliver H.G. Wilder-Smith ◽  
Asbjørn M. Drewes
Keyword(s):  
Chronic Pancreatitis ◽  
Quantitative Sensory Testing ◽  
Sensory Testing

scholarly journals Quantitative Sensory Testing Predicts Pregabalin Efficacy in Painful Chronic Pancreatitis

PLoS ONE ◽  
2013 ◽  
Vol 8 (3) ◽  
pp. e57963 ◽  
Author(s):  
Søren S. Olesen ◽  
Carina Graversen ◽  
Stefan A. W. Bouwense ◽  
Harry van Goor ◽  
Oliver H. G. Wilder-Smith ◽  
...  
Keyword(s):  
Chronic Pancreatitis ◽  
Quantitative Sensory Testing ◽  
Sensory Testing

Rationale for and Development of the Pancreatic Quantitative Sensory Testing Consortium to Study Pain in Chronic Pancreatitis

Pancreas ◽  
2021 ◽  
Vol 50 (9) ◽  
pp. 1298-1304
Author(s):  
Anna Evans Phillips ◽  
Mahya Faghih ◽  
Vikesh K. Singh ◽  
Søren Schou Olesen ◽  
Louise Kuhlmann ◽  
...  
Keyword(s):  
Chronic Pancreatitis ◽  
Quantitative Sensory Testing ◽  
Sensory Testing
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