Prognostic value of red blood cell distribution width (RDW) and BISAP in predicting prognosis of acute pancreatitis

Pancreatology ◽  
2019 ◽  
Vol 19 ◽  
pp. S189
Author(s):  
A. del Val ◽  
J.M. Tenías ◽  
S. Béjar ◽  
N. García Morales ◽  
M. García Campos ◽  
...  
Keyword(s):  
Acute Pancreatitis ◽  
Blood Cell ◽  
Red Blood Cell ◽  
Prognostic Value ◽  
Cell Distribution ◽  
Distribution Width ◽  
Red Blood Cell Distribution

Prognostic Value of Red Blood Cell Distribution Width in Transcatheter Aortic Valve Replacement Patients

2021 ◽  
pp. 155698452110413
Author(s):  
Seyed Hossein Aalaei-Andabili ◽  
R. David Anderson ◽  
Anthony A. Bavry ◽  
Brian Barr ◽  
George J. Arnaoutakis ◽  
...  
Keyword(s):  
Aortic Valve ◽  
Aortic Valve Replacement ◽  
Blood Cell ◽  
Red Blood Cell ◽  
Transcatheter Aortic Valve Replacement ◽  
Prognostic Value ◽  
Cell Distribution ◽  
Distribution Width ◽  
Transcatheter Aortic Valve ◽  
Red Blood Cell Distribution

Objective Elevated red blood cell distribution width (RDW) level has been shown to be associated with poor outcomes in patients with cardiovascular disease. Limited data are available regarding the prognostic value of RDW in transcatheter aortic valve replacement (TAVR) patients. Therefore, we aimed to investigate the impact of RDW variation on outcomes of TAVR patients. Methods From March 20, 2012, to February 20, 2020, the pre-TAVR RDW levels of 1,163 consecutive TAVR patients were examined. Receiver operating curves were set to define the most accurate cut-point, which was subsequently validated in our validation set. Associations of RDW levels with early and long-term outcomes were investigated. Results A total of 988 patients were eligible for the analysis. Patients with 30-day, 1-year, and 7-year mortality had significantly higher pre-TAVR RDW levels (15.8% [12.9-19.1] vs 14.7% [11.6-26.3], P = 0.01; 16% [12.3-26.3] vs 14.7% [11.6-24.3], P < 0.001; 15.6% [12.3-26.3] vs 14.6% [11.6-24.3], P < 0.001, respectively). A RDW of 14.5% was found as the most sensitive and specific cut-point for mortality at 1 and 7 years (HR = 2.6, 95% CI: 1.6-4.2, P < 0.001; HR = 1.8, 95% CI: 1.3-2.4, P < 0.001), with mortality of 22% versus 10% at 1 year ( P < 0.001) and 37% versus 27% at 7 years ( P < 0.001) in patients with RDW ≥14.5% versus those with RDW <14.5%. Conclusions RDW is an important prognostic factor in TAVR patients. A RDW level higher than 14.5% is significantly associated with post-TAVR early and late mortality. RDW levels should be incorporated into current risk assessment models as an additional variable to predict post-TAVR outcomes.

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