Pancreatic juice cytology with the cellblock method in patients with branch-duct type intraductal papillary mucinous neoplasms of the pancreas

Pancreatology ◽  
2016 ◽  
Vol 16 (4) ◽  
pp. S159
Author(s):  
Shinsuke Koshita ◽  
Yutaka Noda ◽  
Kei Ito ◽  
Yoshihide Kanno ◽  
Takahisa Ogawa ◽  
...  
Keyword(s):  
Pancreatic Juice ◽  
Intraductal Papillary Mucinous Neoplasms ◽  
Branch Duct ◽  
Mucinous Neoplasms ◽  
Branch Duct Type ◽  
Pancreatic Juice Cytology

scholarly journals Clinical Impact of the KL-6 Concentration of Pancreatic Juice for Diagnosing Pancreatic Masses

2015 ◽  
Vol 2015 ◽  
pp. 1-6 ◽  
Author(s):  
Kazuya Matsumoto ◽  
Yohei Takeda ◽  
Kenichi Harada ◽  
Takumi Onoyama ◽  
Soichiro Kawata ◽  
...  
Keyword(s):  
Pancreatic Juice ◽  
Clinical Impact ◽  
Intraductal Papillary Mucinous Neoplasms ◽  
Inflammatory Lesions ◽  
Mucinous Neoplasms ◽  
Pancreatic Masses ◽  
Concentration Measurements ◽  
Pancreatic Juice Cytology ◽  
Sensitivity Specificity

Background and Aim. Pancreatic juice cytology (PJC) is considered optimal for differentially diagnosing pancreatic masses, but the accuracy of PJC ranges from 46.7% to 93.0%. The aim of this study was to evaluate the clinical impact of measuring the KL-6 concentration of pancreatic juice for diagnosing pancreatic masses.Methods. PJC and the KL-6 concentration measurements of pancreatic juice were performed for 70 consecutive patients with pancreatic masses (39 malignancies and 31 benign).Results. The average KL-6 concentration of pancreatic juice was significantly higher for pancreatic ductal adenocarcinomas (PDACs) (167.7±396.1 U/mL) and intraductal papillary mucinous carcinomas (IPMCs) (86.9±21.1 U/mL) than for pancreatic inflammatory lesions (17.5±15.7 U/mL,P=0.034) and intraductal papillary mucinous neoplasms (14.4±2.0 U/mL,P=0.026), respectively. When the cut-off level of the KL-6 concentration of pancreatic juice was 16 U/mL, the sensitivity, specificity, and accuracy of the KL-6 concentration of pancreatic juice alone were 79.5%, 64.5%, and 72.9%, respectively. Adding the KL-6 concentration of pancreatic juice to PJC when making a diagnosis caused the values of sensitivity and accuracy of PJC to increase by 15.3% (P=0.025) and 8.5% (P=0.048), respectively.Conclusions. The KL-6 concentration of pancreatic juice may be as useful as PJC for diagnosing PDACs.

scholarly journals Pancreatic juice cytology and subclassification of intraductal papillary mucinous neoplasms of the pancreas

Suizo ◽  
2007 ◽  
Vol 22 (4) ◽  
pp. 519-520
Author(s):  
Yasuhiro Hibi ◽  
Noriyoshi Fukushima ◽  
Akihiko Tsuchida ◽  
Atsushi Sofuni ◽  
Takao Itoi ◽  
...  
Keyword(s):  
Pancreatic Juice ◽  
Intraductal Papillary Mucinous Neoplasms ◽  
Mucinous Neoplasms ◽  
Pancreatic Juice Cytology
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