Prevalence of exocrine pancreatic insufficiency in patients with chronic pancreatitis without follow-up: Nutritional status and quality of life. PANCR-EVOL study

Pancreatology ◽  
2016 ◽  
Vol 16 (3) ◽  
pp. S68-S69
Author(s):  
Marra-Lopez Valenciano Carlos ◽  
Marín Serrano Eva ◽  
Bolado Concejo Federico ◽  
Francisco González María ◽  
Martínez-Moneo Emma ◽  
...  
Author(s):  
M. V. Malykh ◽  
E. A. Dubtsova ◽  
L. V. Vinokurova ◽  
M. A. Kiryukova ◽  
D. S. Bordin

Changes in the exocrine function of the pancreas often develops after proximal and distal resections. Exocrine pancreatic insufficiency (EPI) is characterized by a reduced secretion of pancreatic enzymes, because of which the digestion and absorption of nutrients is impaired. Clinical manifestations of EPI and, as a consequence, changes in nutritional status significantly affect the quality of life of patients.


2010 ◽  
Vol 76 (10) ◽  
pp. 1071-1074 ◽  
Author(s):  
Jonathan C. King ◽  
Shannon Abeywardina ◽  
James J. Farrell ◽  
Howard A. Reber ◽  
O. Joe Hines

Chronic pancreatitis is a debilitating disease resulting in pain, intestinal malabsorption, endocrine dysfunction, and poor quality of life (QoL). Our aim was to analyze surgical outcomes for patients with chronic pancreatitis. Data for patients undergoing operations for chronic pancreatitis between 1990 and 2009 were reviewed. Demographics, operative and perioperative data, and survival were catalogued. QoL was determined (Short Form 36 and European Organisation for Research and Treatment of Cancer Quality of Life Questionnaire + PAN-26) and compared with historical controls. The mean age was 51 ± 2 years, 38 patients were male (53%), the most common indication was pain (71%), the etiology of pancreatitis often was alcohol, and most patients underwent a Whipple procedure (56%). Operative time was 316 ± 17 minutes and blood loss was 363 ± 75 mL. There were 34 complications in 30 patients (42%) and one death. QoL surveys were administered for 25 of 55 (45%) surviving patients at a mean follow-up of 72 ± 16 months. Mean survival was 99 ± 9 months, whereas 5- and 10-year survival were 86 and 75 per cent. QoL scores were uniformly better than historical controls. Our data demonstrate that operations for chronic pancreatitis can be performed with acceptable morbidity and mortality. Patients have excellent survival and improved QoL compared with historical controls. Surgery is an effective and durable treatment option for patients with chronic pancreatitis.


2018 ◽  
Vol 41 (2) ◽  
pp. 77-86 ◽  
Author(s):  
Carlos Marra-Lopez Valenciano ◽  
Federico Bolado Concejo ◽  
Eva Marín Serrano ◽  
Judith Millastre Bocos ◽  
Emma Martínez-Moneo ◽  
...  

Pancreatology ◽  
2015 ◽  
Vol 15 (3) ◽  
pp. e7
Author(s):  
C. Marra-López Valenciano ◽  
E. Marín Serrano ◽  
F. Bolado Concejo ◽  
M. Francisco Gonzalez ◽  
E. Martinez Moneo ◽  
...  

Pancreatology ◽  
2015 ◽  
Vol 15 (3) ◽  
pp. S78-S79
Author(s):  
Carlos Marra-López Valenciano ◽  
Eva Marin Serrano ◽  
Federico Bolado Concejo ◽  
Maria Francisco Gonzalez ◽  
Emma Martínez Moneo ◽  
...  

2021 ◽  
Vol 73 (9) ◽  
pp. 576-586
Author(s):  
Chophaka Suttipong ◽  
Siriorn Sindhu ◽  
Ketsarin Utriyaprasit ◽  
Cherdsak Iramaneerat

Objective: The present study has been aimed at constructing a causal model to determine factors affecting healthrelatedquality of life (HRQoL) in postoperative patients with colorectal cancer (CRC) following discharge.Materials and Methods: A cross-sectional study was conducted with 396 postoperative CRC cancer patients fromten tertiary hospitals representing each of the four Regions of Thailand. Data was collected through a standardquestionnaire. Structure equation modeling (SEM) was applied to analyze data.Results: The findings revealed that the majority of patients with CRC surgery had a moderate HRQoL. One hundredand twenty-three patients (31.1%) had complications. SEM showed a good fit with ƛ2=40.347, df=28, p=0.062,GFI=0.980, CFI=0.959 and RMSEA=0.033. The final model showed that age, stage of cancer and healthcare servicebeing received following CRC surgery had direct effects on HRQoL. Nutritional status and follow-up outpatientclinic had indirect effects on HRQoL during postoperative complications. Moreover, social support and primaryfamily caregiver support had indirect effects on HRQoL through self-management capacity.Conclusion: The findings of this study emphasized the importance of implementing effective strategies to improvequality of life among postoperative patients with CRC after discharge and indicated these strategies should focuson quality of healthcare service following CRC surgery, self-management capacity and prevention of postoperativecomplications. Postoperative complications can be reduced by providing effective follow-up in outpatient clinicsand nutritional status management, consequently improving quality of life among this population.


2018 ◽  
Vol 4 (Supplement 2) ◽  
pp. 173s-173s
Author(s):  
Y.-F. Chang ◽  
Y.-C. Yu ◽  
J. Tsai Lai

Background and context: Since 1982, cancer has been the leading cause of death in Taiwan, claiming more than 40,000 lives each year. This not only caused huge medical expenses, but also affected the quality of life of patients and their families. However, many cancer survivors and their caregivers do not fully understand lifestyle advice, including nutrition and dietary behaviors, to lower the progression of the disease. Due to cancer and painstaking treatment, cancer patients often suffer from inadequate calories intake and serious body weight (BW) loss, which is highly related to malnutrition or cancer cachexia. After they leave the hospital, they still need nutritional guidance; therefore, the importance of providing nutrition services in the community should be emphasized. Aim: To help cancer survivors achieve better nutritional status by teaching them how to have adequate calories intakes and maintain BW that they're supposed to have better quality of life. Strategy/Tactics: (1) Cancer survivors with nutritional needs were referred from 66 cooperative cancer resources centers of hospitals nationwide. (2) Dietitians assess their nutritional conditions and provide nutritional guidance. (3) Deliver free nutritional supplements to the cancer survivors who are financially disadvantaged or have dysphagia problems. Program/Policy process: The registered dietitians conducted nutritional education through nutrition counseling and guidance. For those who are financially disadvantaged or have dysphagia problems, the 24-hour dietary recall and PG-SGA scale were used to assess the survivors' nutritional status, including BW and calories intake, then free nutritional supplements according to their needs and a regular follow-up to collect their BW and nutritional information changes after our interventions were done. Outcomes: From 2016 to 2017, a total of 434 of cancer survivors who have financial difficulties or dysphagia problems accepted the free nutritional supplements and nutritional guidance services. 178 survivors completed follow-up and collected nutritional information. 40.4% of them are head and neck cancers, 38.2% are digestive system-related cancers that were in poor eating conditions. After our interventions, 70.2% of these survivors can maintain or increase their BW with average BW 57.9 ± 12.8 kg; and 77.0% can maintain or increase the calories intake, which average increased from 1798 ± 252.5 kcal/day to 1541.6 ± 347.9 kcal/day. What was learned: We can effectively help cancer survivors achieve adequate calories intakes and maintain BW to prevent the occurrence of malnutrition by providing the services of nutritional supplements and nutritional guidance.


2021 ◽  
Vol 17 (4) ◽  
pp. 52-61
Author(s):  
M.V. Malykh ◽  
◽  
E.A. Dubtsova ◽  
L.V. Vinokurova ◽  
M.A. Kiryukova ◽  
...  

Exo- and/or endocrine pancreatic insufficiency are the complications and diagnostic criteria of chronic pancreatitis. Recently expanded surgical activity in pancreatic diseases prolongs overall survival in such patients. However, patients’ quality of life decreases due to exo- and endocrine pancreatic insufficiency. Timely diagnosis and adequate treatment of the conditions are based on the lab assessment of pancreatic function. The paper presents diagnostic methods, their sensitivity, specificity, and diagnostic role.


2018 ◽  
Vol 119 (10) ◽  
pp. 1185-1194 ◽  
Author(s):  
Marije N. van Doorn-van Atten ◽  
Annemien Haveman-Nies ◽  
Marit M. van Bakel ◽  
Monique Ferry ◽  
Maite Franco ◽  
...  

AbstractThis study aimed to evaluate the effects of an intervention including nutritional telemonitoring, nutrition education, and follow-up by a nurse on nutritional status, diet quality, appetite, physical functioning and quality of life of Dutch community-dwelling elderly. We used a parallel arm pre-test post-test design with 214 older adults (average age 80 years) who were allocated to the intervention group (n97) or control group (n107), based on the municipality. The intervention group received a 6-month intervention including telemonitoring measurements, nutrition education and follow-up by a nurse. Effect measurements took place at baseline, after 4·5 months, and at the end of the study. The intervention improved nutritional status of participants at risk of undernutrition (β(T1)=2·55; 95 % CI 1·41, 3·68;β(T2)=1·77; 95 % CI 0·60, 2·94) and scores for compliance with Dutch guidelines for the intake of vegetables (β=1·27; 95 % CI 0·49, 2·05), fruit (β=1·24; 95 % CI 0·60, 1·88), dietary fibre (β=1·13; 95 % CI 0·70, 1·57), protein (β=1·20; 95 % CI 0·15, 2·24) and physical activity (β=2·13; 95 % CI 0·98, 3·29). The intervention did not have an effect on body weight, appetite, physical functioning and quality of life. In conclusion, this intervention leads to improved nutritional status in older adults at risk of undernutrition, and to improved diet quality and physical activity levels of community-dwelling elderly. Future studies with a longer duration should focus on older adults at higher risk of undernutrition than this study population to investigate whether the impact of the intervention on nutritional and functional outcomes can be improved.


Sign in / Sign up

Export Citation Format

Share Document