Analyzing Relative Flow Speeds in Diabetic Retinopathy Using Variable Interscan Time Analysis OCT Angiography

2021 ◽  
Vol 5 (1) ◽  
pp. 49-59
Author(s):  
Malvika Arya ◽  
Marco Bonini Filho ◽  
Carl B. Rebhun ◽  
Eric M. Moult ◽  
Byungkung Lee ◽  
...  
2018 ◽  
Vol 2 (4) ◽  
pp. 306-319 ◽  
Author(s):  
Carl B. Rebhun ◽  
Eric M. Moult ◽  
Stefan B. Ploner ◽  
Carlos Moreira Neto ◽  
A. Yasin Alibhai ◽  
...  

2017 ◽  
Vol 2017 ◽  
pp. 1-14 ◽  
Author(s):  
Mathilde M. Goudot ◽  
Anne Sikorav ◽  
Oudy Semoun ◽  
Alexandra Miere ◽  
Camille Jung ◽  
...  

Purpose. To evaluate the capacity of OCT angiography (OCTA) for detecting infraclinical lesions in parafoveal capillaries in diabetic patients without diabetic retinopathy (DR). Methods. This prospective observational cross-sectional case-control study analyzed the superficial and deep capillary plexuses (SCP and DCP) on macular OCTA scans (3 × 3 mm) centered on the fovea. We compared 22 diabetic patients (34 eyes included) without DR diagnosis on color fundus photographs, with 22 age- and gender-matched nondiabetic controls (40 eyes included). Qualitative analysis concerned morphological ischemic capillary alterations. Quantitative analysis measured foveal avascular zone (FAZ) size, parafoveal capillary density, and enlargement coefficient of FAZ between SCP and DCP. Results. Neither the qualitative nor quantitative parameters were significantly different between both groups. No microaneurysms or venous tortuosity was observed in any of the analyzed images. On the SCP, the mean FAZ area was 0.322 ± 0.125 mm2 in diabetic patients and 0.285 ± 0.150 mm2 in controls, P=0.31. On the DCP, the mean FAZ area was 0.444 ± 0.153 mm2 in cases and 0.398 ± 0.138 mm2 in controls, P=0.20. Conclusion. OCTA did not detect infraclinical qualitative or quantitative differences in parafoveal capillaries of diabetic patients without DR in comparison with nondiabetic controls.


2018 ◽  
Vol 142 ◽  
pp. 243-253 ◽  
Author(s):  
Guodong Liu ◽  
Ding Xu ◽  
Fang Wang

Biomedicines ◽  
2021 ◽  
Vol 10 (1) ◽  
pp. 88
Author(s):  
Ana Boned-Murillo ◽  
Henar Albertos-Arranz ◽  
María Dolores Diaz-Barreda ◽  
Elvira Orduna-Hospital ◽  
Ana Sánchez-Cano ◽  
...  

Background: Diabetic retinopathy (DR) is the leading cause of legal blindness in the working population in developed countries. Optical coherence tomography (OCT) angiography (OCTA) has risen as an essential tool in the diagnosis and control of diabetic patients, with and without DR, allowing visualisation of the retinal and choroidal microvasculature, their qualitative and quantitative changes, the progression of vascular disease, quantification of ischaemic areas, and the detection of preclinical changes. The aim of this article is to analyse the current applications of OCTA and provide an updated overview of them in the evaluation of DR. Methods: A systematic literature search was performed in PubMed and Embase, including the keywords “OCTA” OR “OCT angiography” OR “optical coherence tomography angiography” AND “diabetes” OR “diabetes mellitus” OR “diabetic retinopathy” OR “diabetic maculopathy” OR “diabetic macular oedema” OR “diabetic macular ischaemia”. Of the 1456 studies initially identified, 107 studies were screened after duplication, and those articles that did not meet the selection criteria were removed. Finally, after looking for missing data, we included 135 studies in this review. Results: We present the common and distinctive findings in the analysed papers after the literature search including the diagnostic use of OCTA in diabetes mellitus (DM) patients. We describe previous findings in retinal vascularization, including microaneurysms, foveal avascular zone (FAZ) changes in both size and morphology, changes in vascular perfusion, the appearance of retinal microvascular abnormalities or new vessels, and diabetic macular oedema (DME) and the use of deep learning technology applied to this disease. Conclusion: OCTA findings enable the diagnosis and follow-up of DM patients, including those with no detectable lesions with other devices. The evaluation of retinal and choroidal plexuses using OCTA is a fundamental tool for the diagnosis and prognosis of DR.


2021 ◽  
Vol 14 (3) ◽  
pp. 124-130
Author(s):  
A. N. Stulova ◽  
N. S. Semenova ◽  
A. V. Zheleznyakova ◽  
V. S. Akopyan ◽  
D. V. Lipatov

2017 ◽  
Vol 139 ◽  
pp. 191-203 ◽  
Author(s):  
Peter L. Nesper ◽  
Brian T. Soetikno ◽  
Hao F. Zhang ◽  
Amani A. Fawzi

2020 ◽  
Vol 4 (4) ◽  
pp. 415-424
Author(s):  
FuPeng Wang ◽  
Steven S. Saraf ◽  
Qinqin Zhang ◽  
Ruikang K. Wang ◽  
Kasra A. Rezaei

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