Thick Epiretinal Membranes Associated with Lamellar Macular Holes

2017 ◽  
Vol 1 (6) ◽  
pp. 473
Author(s):  
Jaclyn L. Kovach ◽  
Brandon Lujan
Keyword(s):  
Epiretinal Membranes ◽  
Macular Holes

scholarly journals Optical coherence tomography assessment for attached posterior vitreous in eyes with macular holes and epiretinal membranes

2018 ◽  
Vol 1 (1) ◽  
pp. 18-22
Author(s):  
Petros Aristodemou ◽  
Marten E. Brelen ◽  
Nishant Kumar ◽  
Richard Markham ◽  
Richard J. Haynes ◽  
...  
Keyword(s):  
Optical Coherence Tomography ◽  
Optical Coherence ◽  
Epiretinal Membranes ◽  
Macular Holes

scholarly journals Evaluation of TGF-Beta 2 and VEGFα Gene Expression Levels in Epiretinal Membranes and Internal Limiting Membranes in the Course of Retinal Detachments, Proliferative Diabetic Retinopathy, Macular Holes, and Idiopathic Epiretinal Membranes

2018 ◽  
Vol 2018 ◽  
pp. 1-6
Author(s):  
Joanna Stafiej ◽  
Karolina Kaźmierczak ◽  
Katarzyna Linkowska ◽  
Paweł Żuchowski ◽  
Tomasz Grzybowski ◽  
...  
Keyword(s):  
Gene Expression ◽  
Expression Profiles ◽  
Rna Extraction ◽  
Retinal Diseases ◽  
Epiretinal Membranes ◽  
Expression Levels ◽  
Macular Holes ◽  
Retinal Disorders ◽  
Pars Plana ◽  
Gene Expression Levels

Purpose. To evaluate the expression profiles of the VEGFα and TGFβ in the ERMs and ILMs in retinal disorders. Methods. In this nonrandomized prospective study, 75 patients (34 females and 41 males) referred to pars plana vitrectomy (PPV) due to different retinal diseases were enrolled to the study. The samples of ERMs and ILMs collected during PPV were immediately put in TRIzol® Reagent (Life Technologies, USA) and stored at −70°C until RNA extraction. Gene expression analysis was done with TaqMan® Gene Expression Assays (Applied Biosystems, USA) following the manufacturer’s instructions. Results. The gene expression levels of VEGFα as well as of TGFβ2 were significantly higher in ERMs than in ILMs in all studied groups. The level of TGFβ2 expression exhibits a significantly lower values in iERMs as compared with the RRD group (p=0.043). There were differences in TGFβ2 expression in ILM in groups studied: DR versus RRD, p=0.003; DR versus iERM, p=0,047; and iERM versus RRD, p=0.004. Conclusions. Our results revealed that factors associated with angiogenesis and wound healing processes in eyes with RRD, PDR, iERM, and MH were more upregulated in ERMs than in ILMs. This may indicate that ILM is not responsible for reproliferation and its peeling should be avoided in routine PPV.

scholarly journals Spectral Domain Optical Coherence Tomography in the Diagnosis and Management of Vitreoretinal Interface Pathologies

2012 ◽  
Vol 2012 ◽  
pp. 1-7 ◽  
Author(s):  
Yoreh Barak ◽  
Mark A. Ihnen ◽  
Shlomit Schaal
Keyword(s):  
Optical Coherence Tomography ◽  
Image Interpretation ◽  
Posterior Vitreous Detachment ◽  
Spectral Domain ◽  
Optical Coherence ◽  
Vitreoretinal Interface ◽  
Epiretinal Membranes ◽  
Macular Holes ◽  
Practice Knowledge ◽  
Sd Oct

The introduction of spectral domain optical coherence tomography (SD-OCT) has enhanced Vitreoretinal Interface (VRI) imaging considerably and facilitated the diagnosis, followup, prognosis determination, and management of VRI-associated pathologies. HR-OCT became a common practical tool seen in almost every ophthalmology practice. Knowledge of SD-OCT image interpretation and recognition of pathologies are required for all ophthalmologists. This paper methodically reviews the normal aging process of the VRI and discusses several commonly encountered VRI pathologies. The role of SD-OCT imaging in VRI-associated disorders such as posterior vitreous detachment, vitreomacular traction syndrome, idiopathic epiretinal membranes, lamellar holes, pseudoholes, and full thickness macular holes is portrayed. Future perspectives of new OCT technologies based on SD-OCT are discussed.

scholarly journals Ocular abnormalities in a large Western China patient cohort with Retinitis Pigmentosa

2020 ◽  
Author(s):  
Lian Tan ◽  
Yanling Long ◽  
Ziyang Li ◽  
Xi Ying ◽  
Jiayun Ren ◽  
...  
Keyword(s):  
Visual Acuity ◽  
Retinitis Pigmentosa ◽  
Macular Oedema ◽  
Western China ◽  
Vitreomacular Traction ◽  
Cystoid Macular Oedema ◽  
Epiretinal Membranes ◽  
Ocular Abnormalities ◽  
Vitreomacular Traction Syndrome ◽  
Macular Holes

Abstract Background: To report the prevalence of ocular abnormalities and investigate visual acuity in a large Western China cohort of retinitis pigmentosa (RP) patients.Methods: A retrospective study was performed, reviewing the medical records and ophthalmic examination reports of 2,127 eyes from 1,065 RP patients in one eye hospital. The authors investigated the prevalence of ocular abnormalities and the relationship between best corrected visual acuity (BCVA) and macular abnormalities.Results: Nyctalopia (58.2%) and blurred vision (27.1%) were the leading consultation causes. BCVA measurements in the better eyes at first clinical presentation showed that 304 patients (28.5%) were categorised as blind and 220 patients (20.7%) as low vision. The most common ocular abnormalities were cataracts (43.1%) and macular abnormalities (59.7%), including epiretinal membranes (51.1%), cystoid macular oedema (18.4%), vitreomacular traction syndrome (2.4%), macular holes (2.3%) and choroidal neovascular membranes (0.05%). Glaucoma was found in 35 eyes (1.6%). The proportions of epiretinal membranes (P = 0.001) and macular holes (P = 0.008) increased significantly with age. The proportions of vitreomacular traction syndrome (P = 0.003) and epiretinal membranes (P < 0.001) in pseudophakia and aphakia eyes were significantly higher than in eyes that had not received operations (including cataracts and clear lens). Cystoid macular oedema was significantly associated with poorer visual acuity in RP patients with clear lens (P = 0.002).Conclusion: Cataracts and macular abnormalities are common in RP patients. In the macular abnormalities, cystoid macular oedema may have a negative effect on BCVA in RP patients with clear lens.

scholarly journals Multimodal Imaging of Lamellar Macular Holes

2021 ◽  
Vol 2021 ◽  
pp. 1-17
Author(s):  
Roberto dell’Omo ◽  
Mariaelena Filippelli ◽  
Serena De Turris ◽  
Andrea Govetto ◽  
Pasquale Napolitano ◽  
...  
Keyword(s):  
Imaging Modality ◽  
Imaging Techniques ◽  
Fundus Autofluorescence ◽  
Fundus Photography ◽  
Foveal Avascular Zone ◽  
Retinal Surface ◽  
Epiretinal Membranes ◽  
Morphologic Characteristics ◽  
Macular Holes ◽  
Vascular Plexuses

Evolution of imaging techniques has renewed interest in the diagnosis of lamellar macular hole (LMH) and greatly implemented the possibilities of gaining more detailed insights into its pathogenesis. Among noninvasive techniques, optical coherence tomography (OCT) is considered the primary examination modality to study LMHs, given its ability to image foveal structure and its widespread availability. OCT also allows to resolve the epiretinal materials associated with LMH, i.e., tractional epiretinal membranes (ERMs) and epiretinal proliferation (EP). En face OCT reconstructions are useful to confirm the foveal abnormalities shown by the eyes with LMH, whereas OCT angiography may reveal alterations of the size and shape of the foveal avascular zone and alterations of the density of the superficial and deep vascular plexuses. On slit-lamp biomicroscopy or fundus camera examination, LMH appears as a round or oval, reddish lesion at the center of the macula, slightly darker than the surrounding retina. The associated tractional ERM, causing wrinkling and glistening of the retinal surface, is usually readily appreciable, whereas EP is hardly apparent on biomicroscopy or fundus photography since the retina surface appears smooth. When imaged with blue fundus autofluorescence (B-FAF) imaging, LMHs are characterized by an increased autofluorescent signal, the intensity of which does not correlate with the thickness of the residual outer retinal tissue. Green reflectance and blue reflectance (BR) images clearly show the increased reflection and wrinkling of the retinal surface caused by tractional ERM associated with LMH. BR and multicolor imaging enable the visualization of EP associated with LMH in the form of a sharply demarcated dark area and in the form of a yellowish area surrounding the hole, respectively. Scarce data regarding invasive imaging techniques, such as fluorescein angiography, for the study of LMH are available in the literature. The aim of this review is to evaluate the contribution that each imaging modality can provide to study the morphologic characteristics of LMH.

Imaging of Epiretinal Membranes in Macular Holes by Scanning Laser Ophthalmoscopy

1996 ◽  
Vol 121 (2) ◽  
pp. 177-180 ◽  
Author(s):  
JUN AKIBA ◽  
SATOSHI ISHIKO ◽  
TAIICHI HIKICHI ◽  
HIRONOBU OGASAWARA ◽  
NORIHIKO YANAGIYA ◽  
...  
Keyword(s):  
Scanning Laser ◽  
Scanning Laser Ophthalmoscopy ◽  
Epiretinal Membranes ◽  
Macular Holes

Vitreoretinal

2018 ◽  
pp. 521-567
Keyword(s):  
Retinal Detachment ◽  
Posterior Vitreous Detachment ◽  
Epiretinal Membranes ◽  
Anatomy And Physiology ◽  
Retinal Degenerations ◽  
Macular Holes ◽  
Retinal Breaks ◽  
Clinical Presentations ◽  
Vitreoretinal Disease ◽  
Wide Range

‘Vitreoretinal’ provides the reader with a practical approach to the assessment and management of vitreoretinal disease. After outlining the relevant anatomy and physiology of the relevant structures, the chapter addresses the key clinical presentations arising from vitreoretinal disease, notably peripheral retinal degenerations, retinal breaks, posterior vitreous detachment, retinal detachment (rhegmatogenous, tractional and exudative), retinoschisis, epiretinal membranes, macular holes and a wide range of rarer conditions. Using a patient-centred approach the key clinical features, investigations and treatment (medical and surgical) are described for each condition.

Ultrastructure of epiretinal membranes associated with macular holes

1998 ◽  
Vol 236 (4) ◽  
pp. 248-254 ◽  
Author(s):  
Elisabeth M. Messmer ◽  
Hans-Peter Heidenkummer ◽  
A. Kampik
Keyword(s):  
Epiretinal Membranes ◽  
Macular Holes
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