Graft Failure as a Secondary Complication of Herpetic Neurotrophic Corneal Ulcer Treatment in a Patient With a History of Descemet's Stripping Automated Endothelial Keratoplasty and Penetrating Keratoplasty: A Case Report and Review

2011 ◽  
Vol 82 (6) ◽  
pp. 365
Author(s):  
Marc Lay ◽  
Jeffrey T. Joy
Keyword(s):  
Case Report ◽  
Graft Failure ◽  
Penetrating Keratoplasty ◽  
Corneal Ulcer ◽  
Endothelial Keratoplasty ◽  
History Of ◽  
Ulcer Treatment ◽  
Secondary Complication

scholarly journals Descemet membrane suturing to manage recurrent graft detachment in a patient with Descemet membrane endothelial keratoplasty on failed penetrating keratoplasty

2021 ◽  
Vol 13 ◽  
pp. 251584142110277
Author(s):  
Zahra Ashena ◽  
Thomas Hickman-Casey ◽  
Mayank A. Nanavaty
Keyword(s):  
Visual Acuity ◽  
Penetrating Keratoplasty ◽  
Anterior Segment ◽  
Endothelial Keratoplasty ◽  
Descemet Membrane Endothelial Keratoplasty ◽  
Descemet Membrane ◽  
Ocular Coherence Tomography ◽  
Corrected Visual Acuity ◽  
Intracameral Injection ◽  
History Of

A 65-year-old patient with history of keratoconus, mild cataract and penetrating keratoplasty over 30 years ago developed corneal oedema subsequent of graft failure with best corrected visual acuity (BCVA) of counting fingers. He underwent a successful cataract surgery combined with a 7.25 mm Descemet’s Membrane Endothelial Keratoplasty (DMEK) with Sodium Hexafluoride (SF6) gas. His cornea remained oedematous inferiorly at 4 weeks, despite two subsequent re-bubbling due to persistent DMEK detachment inferiorly. This was managed by three radial full thickness 10-0 nylon sutures placed in the inferior cornea along with intracameral injection of air. Following this, his anterior segment ocular coherence tomography (OCT) confirmed complete attachment of the graft, and the sutures were removed 4 weeks later. Unaided visual acuity was 20/63 and BCVA was 20/32 after 8 months. DMEK suturing can be helpful in persistent DMEK detachments, which is refractory to repeated re-bubbling due to uneven posterior surface of previous PK.

scholarly journals Lymphocele in a Renal Transplant Recipient During Lymphoscintigraphic Evaluation of Unilateral Leg Oedema: a Case Report

2018 ◽  
Vol 21 (1) ◽  
pp. 43-45
Author(s):  
Shamim MF Begum ◽  
Pupree Mutsuddy ◽  
Sadia Sultana
Keyword(s):  
Case Report ◽  
Renal Transplant ◽  
Early Diagnosis ◽  
Transplant Recipient ◽  
Renal Transplant Recipient ◽  
Lower Limb ◽  
Graft Failure ◽  
Epithelial Lining ◽  
History Of ◽  
Definition Of

Lymphocele is a common lymphatic complication in renal transplant recipient. The definition of lymphocele is a lymph-filled extraperitoneal space, with no epithelial lining. This condition may originate from leakage of lymph from unligated iliac vessels lymphatics of the recipient and/or surgical damage of the graft lymphatics during the procurement. The untreated complications may lead to catastrophic consequences. Early diagnosis and treatment of these complications are paramount to prevent graft failure and other significant morbidities to the patients. Here a case is presented in a haplotype renal transplant recipient showed abnormal radiotracer accumulation in the transplant fossa during lymphoscintigraphic evaluation with history of right lower limb swelling. Bangladesh J. Nuclear Med. 21(1): 43-45, January 2018

scholarly journals Stabilization of Bilateral Progressive Rheumatoid Corneal Melt with Infliximab

2012 ◽  
Vol 2012 ◽  
pp. 1-3 ◽  
Author(s):  
Sheelah F. Antao ◽  
Tariq Ayoub ◽  
Hasan Tahir ◽  
Dipak N. Parmar
Keyword(s):  
Rheumatoid Arthritis ◽  
Case Report ◽  
Amniotic Membrane ◽  
Conventional Treatment ◽  
Penetrating Keratoplasty ◽  
Amniotic Membrane Transplantation ◽  
Cyanoacrylate Glue ◽  
Ocular Discomfort ◽  
History Of ◽  
Ulcerative Keratitis

Purpose. To report the use of infliximab in the rapid stabilization of a case of progressive, bilateral rheumatoid peripheral ulcerative keratitis (PUK) that failed to respond to conventional immunosuppressive therapy.Methods. A single interventional case report.Results. A patient with rheumatoid arthritis presented with bilateral PUK following a 2-month history of ocular discomfort and redness. His systemic prednisolone (PDN) and methotrexate (MTX) were increased and, despite an initial favorable response, bilateral recurrent corneal perforations ensued. Both eyes underwent cyanoacrylate glue repair, amniotic membrane transplantation (AMT), and penetrating keratoplasty (PKP). Recurrence of the disease and bilateral perforations of the second PKP in both eyes prompted administration of intravenous infliximab immediately after the fourth PKP. The disease activity rapidly settled in both eyes, and at eighteen-month followup, after 12 infliximab infusions, the PUK remains quiescent with no further graft thinning or perforation.Conclusion. Infliximab can be used to arrest the progression of severe bilateral rheumatoid PUK in cases that are refractory to conventional treatment.

scholarly journals Recurrence of Avellino Corneal Dystrophy Following Penetrating Keratoplasty: A Case Report

2021 ◽  
Vol 59 (236) ◽  
Author(s):  
Rachana Singh Rana ◽  
Leena Bajracharya ◽  
Reeta Gurung
Keyword(s):  
Case Report ◽  
Penetrating Keratoplasty ◽  
Autosomal Dominant ◽  
Corneal Dystrophy ◽  
Rare Disorder ◽  
Epithelial Defect ◽  
Autosomal Dominant Fashion ◽  
History Of

Granular – lattice (Avellino) corneal dystrophy is inherited in an autosomal dominant fashion which affects stroma of the cornea with recurrent erosions and decreased vision due to clouding of cornea in later stage. We reported a case of 53-year old woman presented with pain and blurring of vision of left eye for 10 days with history of right eye deep anterior lamellar dystrophy and Left eye penetrating keratoplasty 5years back for Avellino dystrophy. On examination right eye graft was clear and left eye showed circular edges of irregular epithelium with patchy stains and epithelial defect suggestive of recurrence of dystrophy. A patient with recurrent corneal erosions and opacity in cornea has to be examined carefully so as not to overlook Avellino corneal dystrophy. Being a rare disorder this case has been reported to draw the attention of ophthalmologists about its recurrence following keratoplasty.

scholarly journals Collagen Corneal Cross-linking in a Keratoconic Eye with Diffuse Corneal Edema

2012 ◽  
Vol 1 (2) ◽  
pp. 134-139
Author(s):  
Hanna Garzozi ◽  
Yossef Pickel ◽  
Ankur Barua
Keyword(s):  
Case Report ◽  
Penetrating Keratoplasty ◽  
Corneal Edema ◽  
Cross Linking ◽  
Endothelial Keratoplasty ◽  
Review Of Literature ◽  
Safety And Efficacy ◽  
Definitive Solution

ABSTRACT Corneal cross-linking has proven safety and efficacy in arresting the progression of keratoconus. Its use has been extended to resolution of corneal edema. We present a case report and review of literature on the treatment of corneal edema using corneal cross-linking. Corneal cross-linking seems to be an effective method in reducing corneal edema at least as a temporary measure till definitive solution, such as penetrating keratoplasty (PKP) or Descemet's stripping automated endothelial keratoplasty (DASEK) is preformed. How to cite this article Barbara R, Garzozi H, Barbara A, Pickel Y, Barua A. Collagen Corneal Cross-linking in a Keratoconic Eye with Diffuse Corneal Edema. Int J Kerat Ect Cor Dis 2012;1(2):134-139.

scholarly journals Non-Descemet Stripping Automated Endothelial Keratoplasty for Bullous Keratopathy in Buphthalmic Eye

2016 ◽  
Vol 7 (2) ◽  
pp. 279-284 ◽  
Author(s):  
Koji Hirano ◽  
Shu Kachi ◽  
Masako Matsuura ◽  
Kazuhide Kawase ◽  
Won Sun Park
Keyword(s):  
Graft Failure ◽  
Penetrating Keratoplasty ◽  
Crystalline Lens ◽  
Bullous Keratopathy ◽  
Topical Steroids ◽  
Endothelial Keratoplasty ◽  
Corrected Visual Acuity ◽  
The Right ◽  
Phakic Eyes

Purpose: To report the 2-year follow-up findings in a patient with buphthalmic bullous keratopathy (BK) who was successfully treated with non-Descemet stripping automated endothelial keratoplasty (nDSAEK). Methods: A 39-year-old man had an endothelial graft of 8.0 mm diameter placed uneventfully using the nDSAEK method for phakic BK with buphthalmos of the left eye. He had had a penetrating keratoplasty in the right eye due to aphakic BK 5 years earlier, which, however, resulted in the invasion of blood vessels and graft failure. Since the left eye was phakic, Descemetorhexis was not performed because the instruments might touch the crystalline lens. The best-corrected visual acuity (BCVA), intraocular pressure (IOP), and endothelial cell density (ECD) were determined at 2 weeks, and at 1, 3, 6, 12, 18 and 24 months after nDSAEK. Results: Twenty-four months after nDSAEK, his left cornea and lens remained clear, and the decimal BCVA was 0.8. However, the ECD of the graft had decreased from 2,274 cells/mm2 before nDSAEK to 539 cells/mm2 24 months after the surgery, and the rate of decrease appeared to be slightly faster than that of former reports. An IOP of >30 mm Hg was recorded at around 2 months after the surgery, but was well controlled by tapering the topical steroids and the addition of topical brinzolamide and latanoprost. Conclusion: Our findings show that nDSAEK can be successfully used to treat buphthalmic BK. We recommend that nDSAEK be considered especially in phakic eyes with a smooth posterior surface around the pupillary area.

scholarly journals Posaconazole in the treatment of refractory Purpureocillium lilacinum (former Paecilomyces lilacinus) keratitis: the salvation when nothing works

2019 ◽  
Vol 12 (4) ◽  
pp. e228645 ◽  
Author(s):  
Mariana Almeida Oliveira ◽  
Analia Carmo ◽  
Andreia Rosa ◽  
Joaquim Murta
Keyword(s):  
Case Report ◽  
Clinical Condition ◽  
Penetrating Keratoplasty ◽  
Contact Lenses ◽  
Clinical Signs ◽  
Paecilomyces Lilacinus ◽  
Purpureocillium Lilacinum ◽  
History Of ◽  
History Of Pain

We report a case of a 41-year-old woman, wearer of contact lenses who was presented to the emergency room with a 2-month history of pain and red eye. She presented with a severe keratitis refractory to quinolones, fortified antibiotics and clotrimazole. Due to the risk of perforation, a tectonic penetrating keratoplasty (PK) was performed. Clinical signs of keratitis recurrence were observed and cultures were positive for Purpureocillium lilacinum (former Paecilomyces lilacinus). The patient did not improve on topical amphotericin B and intracameral voriconazole. Worsening of clinical condition required a new PK. Oral posaconazole was initiated postoperatively and suspended at the fourth postoperative month. The cornea remains clear until the last follow-up visit, 12 months after the second graft. To our knowledge, this is the second case report that documents the effectiveness of oral posaconazole in a refractory P. lilacinus keratitis, resistant to other second-generation triazoles and conventional antifungals.

scholarly journals Descemet Stripping Automated Endothelial Keratoplasty for Repeated Penetrating Keratoplasty Graft Failure

2021 ◽  
Vol 62 (3) ◽  
pp. 394-399
Author(s):  
Gyu Deok Hwang ◽  
Hye Yeon Yun ◽  
Min Ji Ha ◽  
Woong Joo Whang ◽  
Dong Jin Chang ◽  
...  
Keyword(s):  
Graft Failure ◽  
Penetrating Keratoplasty ◽  
Endothelial Keratoplasty
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